Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Scott C. Mauldin"'
Autor:
Ryan Thomas Backer, Alain Merschaert, Matthew J. Fisher, Kuklish Steven Lee, Aaron M. Kempema, Scott C. Mauldin
Publikováno v:
Tetrahedron Letters. 56:2605-2607
Application of an acid-catalyzed thioamidation of β-amino-acrylonitriles to the corresponding β-amino-thioacrylamides toward the synthesis of 3,4-substituted-5-amino-isothiazoles is described. The greatest yields were observed for examples with ele
Autor:
Ryan Thomas Backer, Matthew J. Fisher, Aaron M. Kempema, Alain Merschaert, Scott C. Mauldin, Kuklish Steven Lee
Publikováno v:
ChemInform. 46
The use of an acid-catalyzed thioamidation of unsaturated nitriles for the preparation of substituted-5-amino-isothiazoles, providing a useful complement to the known base-catalyzed procedures.
Autor:
Larry C. Blaszczak, Scott C. Mauldin, Michael S. VanNieuwenhze, James Abraham Aikins, Mohammad Zia-Ebrahimi
Publikováno v:
Journal of the American Chemical Society. 123:6983-6988
A total synthesis of lipid I (4), a membrane-associated intermediate in the bacterial cell wall (peptidoglycan) biosynthesis pathway, is reported. This highly convergent synthesis will enable further studies on bacterial resistance mechanisms and may
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1554-1558
The synthesis of (2Z,4RS)-5-acetamido-4-guanidino-2-benzamidopent-2-enoic acid (sodium salt) 5 is reported. Wittig–Horner olefination of diamino protected propionaldehyde 8 with phosphonoglycine trimethyl ester 11 provided (Z)-olefin methyl ester 1
Publikováno v:
ChemInform. 32
Autor:
Larry C. Blaszczak, Michael S. VanNieuwenhze, James Abraham Aikins, Scott C. Mauldin, Mohammad Zia-Ebrahimi
Publikováno v:
ChemInform. 32
A total synthesis of lipid I (4), a membrane-associated intermediate in the bacterial cell wall (peptidoglycan) biosynthesis pathway, is reported. This highly convergent synthesis will enable further studies on bacterial resistance mechanisms and may
Autor:
William Joseph Hornback, Michael S. VanNieuwenhze, Mohammad Zia-Ebrahimi, Larry C. Blaszczak, Shankar L. Saha, Scott C. Mauldin, James Abraham Aikins, Brian E. Winger
Publikováno v:
ChemInform. 33
Bacterial peptidoglycan is composed of a network of beta-[1,4]-linked glyan strands that are cross-linked through pendant peptide chains. The final product, the murein sacculus, is a single, covalently closed macromolecule that precisely defines the
Autor:
Victor Fuchs, Janice M. Rose, Kollol Pal, Mark L. Behnke, Wolfhard W. Engel, Usha R. Patel, Scot J. Campbell, Suresh R. Kapadia, Julian Adams, Jerry W. Skiles, Joe C. Wu, Gunther Schmidt, Grozinger Karl G, Alan S. Rosenthal, Tracy D. Saboe, Wolfgang G. Eberlein, Jana Vitous, Janice M. Klunder, John R. Proudfoot, Ernest Cullen, Mark T. Skoog, Mcneil Daniel W, Scott C. Mauldin, Grace C. Chow, Karl D. Hargrave
Publikováno v:
Journal of Medicinal Chemistry. 34:2231-2241
Novel pyrido[2,3-b][1,4]benzodiazepinones (I), pyrido[2,3-b][1,5]benzodiazepinones (II), and dipyrido[3,2-b:2',3'-e][1,4]diazepinones (III) were found to inhibit human immunodeficiency virus type 1 (HIV-1) reverse transcriptase in vitro at concentrat
Autor:
Michael S. VanNieuwenhze, Scott C. Mauldin, Larry C. Blaszczak, Brian E. Winger, James Abraham Aikins, Shankar L. Saha, Mohammad Zia-Ebrahimi, William Joseph Hornback
Publikováno v:
Journal of the American Chemical Society. 124(14)
Bacterial peptidoglycan is composed of a network of beta-[1,4]-linked glyan strands that are cross-linked through pendant peptide chains. The final product, the murein sacculus, is a single, covalently closed macromolecule that precisely defines the
Autor:
Scott C. Mauldin, Ronald F. Borne
Publikováno v:
Journal of Heterocyclic Chemistry. 22:693-696
Based upon the structural similarities of cannabinoid derivatives which inhibit the biosynthesis of prostaglandins with those of the potent inhibitor, indomethacin, several cannabinoid derivatives possessing C-3 side chain carboxylic acid functionali