Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Scott C. Kogan"'
Autor:
Astrid Wintering, Anna Hecht, Julia Meyer, Eric B. Wong, Juwita Hübner, Sydney Abelson, Kira Feldman, Vanessa E. Kennedy, Cheryl A.C. Peretz, Deborah L. French, Jean Ann Maguire, Chintan Jobaliya, Marta Rojas Vasquez, Sunil Desai, Robin Dulman, Eneida Nemecek, Hilary Haines, Mahmoud Hammad, Alaa El Haddad, Scott C. Kogan, Zied Abdullaev, Farid F. Chehab, Sarah K. Tasian, Catherine C. Smith, Mignon L. Loh, Elliot Stieglitz
Publikováno v:
Haematologica, Vol 999, Iss 1 (2023)
Mutations in five canonical Ras pathway genes (NF1, NRAS, KRAS, PTPN11 and CBL) are detected in nearly 90% of patients with juvenile myelomonocytic leukemia (JMML), a frequently fatal malignant neoplasm of early childhood. In this report, we describe
Externí odkaz:
https://doaj.org/article/6b7a3df1a4054f309e85875af70a1441
Autor:
Yang Hu, Mimansa Geere, Maham Awan, Andrew D. Leavitt, Laura E. Brown, Hadley J. Pearson, Jocelyn S. Gandelman, Scott C. Kogan
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 1253-1258 (2022)
Background The appearance of bite cells associated with methemoglobinemia can be caused by oxidizing drugs such as dapsone in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency or high drug serum levels. Bite cells are often pathognomo
Externí odkaz:
https://doaj.org/article/e088106cfc1c40729d829fad46ce3a0f
Autor:
Gloria Mas, Na Man, Yuichiro Nakata, Concepcion Martinez-Caja, Daniel Karl, Felipe Beckedorff, Francesco Tamiro, Chuan Chen, Stephanie Duffort, Hidehiro Itonaga, Adnan K. Mookhtiar, Kranthi Kunkalla, Alfredo M. Valencia, Clayton K. Collings, Cigall Kadoch, Francisco Vega, Scott C. Kogan, Lluis Morey, Daniel Bilbao, Stephen D. Nimer
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
During emergency hematopoiesis, hematopoietic stem cells (HSCs) rapidly proliferate to produce myeloid and lymphoid effector cells, a response that is critical against infection or tissue injury. If unresolved, this process leads to sustained inflamm
Externí odkaz:
https://doaj.org/article/2118c0f847304f59b6180d6c918e01a4
Publikováno v:
Haematologica, Vol 108, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/e595d2df5da942aebca49291d259eb56
Autor:
Joseph L. Wiemels, Rong Wang, Mi Zhou, Helen Hansen, Rachel Gallant, Junghyun Jung, Nicholas Mancuso, Adam J. de Smith, Catherine Metayer, Scott C. Kogan, Xiaomei Ma
Publikováno v:
Haematologica, Vol 107, Iss 9 (2022)
Externí odkaz:
https://doaj.org/article/6139f378af0442828f09b444134f2b69
Autor:
Smrithi Sukumar, Melissa Cabero, Sharon Tiu, Margaret C. Fang, Scott C. Kogan, Janice B. Schwartz
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 4, Pp n/a-n/a (2021)
Abstract Background Direct‐acting oral anticoagulants (DOACs) are increasingly used to prevent and treat thromboembolism. Although measurement of DOAC concentrations is not currently recommended as part of routine patient care, measurement of DOAC
Externí odkaz:
https://doaj.org/article/0a302612103c446db244cd46a0ba11a0
Autor:
Jasmine C. Wong, Pedro A. Perez-Mancera, Tannie Q. Huang, Jangkyung Kim, Joaquim Grego-Bessa, Maria del pilar Alzamora, Scott C. Kogan, Amnon Sharir, Susan H. Keefe, Carolina E. Morales, Denny Schanze, Pau Castel, Kentaro Hirose, Guo N. Huang, Martin Zenker, Dean Sheppard, Ophir D. Klein, David A. Tuveson, Benjamin S. Braun, Kevin Shannon
Publikováno v:
JCI Insight, Vol 5, Iss 21 (2020)
Somatic KRAS mutations are highly prevalent in many cancers. In addition, a distinct spectrum of germline KRAS mutations causes developmental disorders called RASopathies. The mutant proteins encoded by these germline KRAS mutations are less biochemi
Externí odkaz:
https://doaj.org/article/3d9175f56bd4469b9994c659c5e9bbbc
Autor:
Amalie B. Nielsen, Mi Zhou, Adam J. de Smith, Rong Wang, Lucie McCoy, Helen Hansen, Libby Morimoto, Kirsten Grønbæk, Christoffer Johansen, Scott C. Kogan, Catherine Metayer, Paige M. Bracci, Xiaomei Ma, Joseph L. Wiemels
Publikováno v:
Haematologica, Vol 104, Iss 11 (2019)
Externí odkaz:
https://doaj.org/article/18878652429f4974b55302c8247d81ff
Autor:
Brie K. Fuqua, Yan Lu, David M. Frazer, Deepak Darshan, Sarah J. Wilkins, Linda Dunn, Alex V. Loguinov, Scott C. Kogan, Pavle Matak, Huijun Chen, Joshua L. Dunaief, Chris D. Vulpe, Gregory J. Anderson
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 4, Pp 405-427 (2018)
Background & Aims: Multicopper ferroxidases (MCFs) facilitate intestinal iron absorption and systemic iron recycling, likely by a mechanism involving the oxidization of Fe2+ from the iron exporter ferroportin 1 for delivery to the circulating Fe3+ ca
Externí odkaz:
https://doaj.org/article/9a243689ff084d4d862aa74169ab9bf1
Autor:
Karen Keeshan, Pauline Vieugué, Shahzya Chaudhury, Loveena Rishi, Coline Gaillard, Lu Liang, Elaine Garcia, Takuro Nakamura, Nader Omidvar, Scott C. Kogan
Publikováno v:
Haematologica, Vol 101, Iss 10 (2016)
The PML/RARA fusion protein occurs as a result of the t(15;17) translocation in the acute promyelocytic leukemia subtype of human acute myeloid leukemia. Gain of chromosome 8 is the most common chromosomal gain in human acute myeloid leukemia, includ
Externí odkaz:
https://doaj.org/article/e5fdec56306042b98bf05fe0f11d75a3