Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Scott C. Kachlany"'
Autor:
Scott C. Kachlany, Brian A. Vega
Publikováno v:
Pathogens, Vol 13, Iss 5, p 354 (2024)
Aggregatibacter actinomycetemcomitans is a Gram-negative oral bacterium that has been primarily studied for its role in causing periodontal disease. The bacterium has also been implicated in several systemic diseases such as endocarditis and soft tis
Externí odkaz:
https://doaj.org/article/2c87a4f1d3ca4be39670ac34af8fb10f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Leukotoxin (LtxA) (Trade name, Leukothera) is a protein that is secreted from the oral bacterium Aggregatibacter actinomycetemcomitans, which targets and kills activated white blood cells (WBCs) by binding to lymphocyte function associated a
Externí odkaz:
https://doaj.org/article/b0c9ebaf770543bda5233b0247bbc1c8
Publikováno v:
Toxins, Vol 11, Iss 9, p 489 (2019)
Aggregatibacter actinomycetemcomitans is an oral pathogen that produces the RTX toxin, leukotoxin (LtxA; Leukothera®). A. actinomycetemcomitans is strongly associated with the development of localized aggressive periodontitis. LtxA acts as a virulen
Externí odkaz:
https://doaj.org/article/b6ac686e545c4aff8f3ae9b5a0b2e468
Autor:
Scott C. Kachlany, Nataliya V. Balashova, Rebecca K. Han, Amy Le, Jason B. Nishikubo, Michael S. Forman
Publikováno v:
Toxins, Vol 2, Iss 12, Pp 2824-2836 (2010)
Aggregatibacter actinomycetemcomitans is an oral pathogen and etiologic agent of localized aggressive periodontitis. The bacterium is also a cardiovascular pathogen causing infective endocarditis. A. actinomycetemcomitans produces leukotoxin (LtxA),
Externí odkaz:
https://doaj.org/article/3710d71cec554ac796707db55c2b4dc2
Autor:
Justin B. Nice, Nataliya V. Balashova, Scott C. Kachlany, Evan Koufos, Eric Krueger, Edward T. Lally, Angela C. Brown
Publikováno v:
Toxins, Vol 10, Iss 10, p 414 (2018)
The Gram-negative bacterium, Aggregatibacter actinomycetemcomitans, has been associated with localized aggressive periodontitis (LAP). In particular, highly leukotoxic strains of A. actinomycetemcomitans have been more closely associated with this di
Externí odkaz:
https://doaj.org/article/909e7435ef784ea5bc8de80623fd5cb5
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Leukotoxin (LtxA) (Trade name, Leukothera) is a protein that is secreted from the oral bacterium Aggregatibacter actinomycetemcomitans, which targets and kills activated white blood cells (WBCs) by binding to lymphocyte function associated antigen-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea130d2383d6f0644a559bedc2f55b07
https://doi.org/10.1038/s41598-021-97545-4
https://doi.org/10.1038/s41598-021-97545-4
Publikováno v:
Infection and immunity. 87(8)
Leukotoxin (LtxA) (trade name, Leukothera) is a protein secreted by the oral bacterium Aggregatibacter actinomycetemcomitans. A. actinomycetemcomitans is an oral pathogen strongly associated with development of localized aggressive periodontitis. Ltx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898fc7f28925f2bf44ea6bb733093f29
https://pubmed.ncbi.nlm.nih.gov/31109948
https://pubmed.ncbi.nlm.nih.gov/31109948
Autor:
Scott C. Kachlany, Angela C. Brown, Evan Koufos, Edward T. Lally, Eric Krueger, Justin B. Nice, Nataliya Balashova
Publikováno v:
Toxins
Volume 10
Issue 10
Toxins, Vol 10, Iss 10, p 414 (2018)
Volume 10
Issue 10
Toxins, Vol 10, Iss 10, p 414 (2018)
The Gram-negative bacterium, Aggregatibacter actinomycetemcomitans, has been associated with localized aggressive periodontitis (LAP). In particular, highly leukotoxic strains of A. actinomycetemcomitans have been more closely associated with this di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6c5a44c75b31c2aaba372e53cffb1d
Autor:
Scott C. Kachlany, Manpreet Kaur
Publikováno v:
Microbiology. 160:2443-2452
Leukotoxin (LtxA; Leukothera), a protein toxin secreted by the oral bacterium Aggregatibacter actinomycetemcomitans, specifically kills white blood cells (WBCs). LtxA binds to the receptor known as lymphocyte function associated antigen-1 (LFA-1), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46a6b939f62339ede40aaa1f58c20cd
https://doi.org/10.1099/mic.0.082347-0
https://doi.org/10.1099/mic.0.082347-0
Autor:
Amariliz Rivera-Medina, Scott C. Kachlany, Vanessa Espinosa, Vahid Rahimian, Anukriti Gupta, Chinnaswamy Kasinathan, Eugenio Capitle, Katie Miro, Helen A. Aguila, Lindsey E. Galusha
Publikováno v:
Journal of Leukocyte Biology. 97:439-446
Allergic asthma is a chronic respiratory disease that results from an exaggerated inflammatory response in the airways. Environment stimuli, such as pollen and HDM, cause activation and migration of inflammatory WBCs into the respiratory tract, where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84cb7888fc4a1f5daede282c636a42a
https://doi.org/10.1189/jlb.5hi0414-196r
https://doi.org/10.1189/jlb.5hi0414-196r