Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Scott C. Fligor"'
Autor:
Scott C. Fligor, Savas T. Tsikis, Thomas I. Hirsch, Ashish Jain, Liang Sun, Shira Rockowitz, Kathleen M. Gura, Mark Puder
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Patients with intestinal failure who receive long-term parenteral nutrition (PN) often develop intestinal failure-associated liver disease (IFALD). Although there are identified risk factors, the early pathogenesis is poorly understood and t
Externí odkaz:
https://doaj.org/article/7c52d7e75d6c46f283bc9179c59ef240
Autor:
Sydney A. Martinez, Scott C. Fligor, Savas Tsikis, Meagan Short, Katie E. Corcoran, Amy Rogers, Kathleen M. Gura, Mark Puder
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background Intestinal malrotation is a rare congenital condition with potentially devastating consequences due to potential volvulus and massive intestinal necrosis. Diagnosis is often delayed and long-term symptoms following surgical correc
Externí odkaz:
https://doaj.org/article/706e6628308d44bbb68561d397c651b1
Autor:
Savas T. Tsikis, Timothy Klouda, Thomas I. Hirsch, Scott C. Fligor, Tiffany Liu, Yunhye Kim, Amy Pan, Mikayla Quigley, Paul D. Mitchell, Mark Puder, Ke Yuan
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 10, Pp 100613- (2023)
Summary: In newborns, developmental disorders such as congenital diaphragmatic hernia (CDH) and specific types of congenital heart disease (CHD) can lead to defective alveolarization, pulmonary hypoplasia, and pulmonary arterial hypertension (PAH). T
Externí odkaz:
https://doaj.org/article/72bf97f28d654e2295cff64d4474e2d7
Autor:
Savas T. Tsikis, Thomas I. Hirsch, Scott C. Fligor, Amy Pan, Malachi M. Joiner, Angela Devietro, Paul D. Mitchell, Hiroko Kishikawa, Kathleen M. Gura, Mark Puder
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Infants with congenital diaphragmatic hernia (CDH) may require cardiopulmonary bypass and systemic anticoagulation. Expeditious lung growth while on bypass is essential for survival. Previously, we demonstrated that heparin impairs lung grow
Externí odkaz:
https://doaj.org/article/92b651fd450e4a1c8548c779a93929c8
Autor:
Bennet S. Cho, Scott C. Fligor, Gillian L. Fell, Jordan D. Secor, Savas T. Tsikis, Amy Pan, Lumeng J. Yu, Victoria H. Ko, Duy T. Dao, Lorenzo Anez-Bustillos, Thomas I. Hirsch, Jenny Lund, Arild C. Rustan, David A. Fraser, Kathleen M. Gura, Mark Puder
Publikováno v:
PLoS ONE, Vol 18, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/28b3051b765841b4942b471325ef0c87
Autor:
Savas T. Tsikis, Scott C. Fligor, Paul D. Mitchell, Thomas I. Hirsch, Sarah Carbeau, Eric First, Greta Loring, Coral Rudie, Steven D. Freedman, Camilia R. Martin, Kathleen M. Gura, Mark Puder
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Background Short bowel syndrome (SBS) is a leading cause of intestinal failure resulting in parenteral nutrition (PN) dependence and nutritional deficiencies. Long-term PN use is associated with the development of sepsis and intestinal failure-associ
Externí odkaz:
https://doaj.org/article/8dc7fea3942a4d308c063825cdd78812
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Lung endothelial cells comprise the pulmonary vascular bed and account for the majority of cells in the lungs. Beyond their role in gas exchange, lung ECs form a specialized microenvironment, or niche, with important roles in health and disease. In e
Externí odkaz:
https://doaj.org/article/72fa38fc87a444e4933779878916fd7a
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Following Kasai hepatic portoenterostomy (HPE), most patients with biliary atresia will eventually require liver transplantation due to progressive cirrhosis and liver failure. Preventing liver transplantation, or even delaying eventual liver transpl
Externí odkaz:
https://doaj.org/article/489b9256f3034a2fbbba21fbfdf60e83
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Free fatty acid receptors (FFARs) are a class of G protein-coupled receptors (GPCRs) that have wide-ranging effects on human physiology. The four well-characterized FFARs are FFAR1/GPR40, FFAR2/GPR43, FFAR3/GPR41, and FFAR4/GPR120. Short-chain (
Externí odkaz:
https://doaj.org/article/529d6a7115fc4873959eed98ecd4ef71
Autor:
Savas Theodore Tsikis, Scott C. Fligor, Jordan D. Secor, Lumeng J. Yu, Amy Pan, Greta Loring, Eric First, Arthur P. Nedder, Robin M. Grammer, Coral Rudie, Kathleen M. Gura, Mark Puder
Publikováno v:
J Surg Res
BACKGROUND: Short bowel syndrome (SBS) results from significant intestinal loss and is characterized by insufficient absorption of nutrients and fluids. Preclinical large animal SBS models typically require parenteral nutrition (PN) support and may n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ec7678fd46c9acc51e16734d74f1f8
https://doi.org/10.1016/j.jss.2022.01.004
https://doi.org/10.1016/j.jss.2022.01.004