Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Scott C Kolbe"'
Optic nerve diffusion tensor imaging after acute optic neuritis predicts axonal and visual outcomes.
Autor:
Anneke van der Walt, Scott C Kolbe, Yejun E Wang, Alexander Klistorner, Neil Shuey, Gelareh Ahmadi, Mark Paine, Mark Marriott, Peter Mitchell, Gary F Egan, Helmut Butzkueven, Trevor J Kilpatrick
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83825 (2013)
BackgroundEarly markers of axonal and clinical outcomes are required for early phase testing of putative neuroprotective therapies for multiple sclerosis (MS).ObjectivesTo assess whether early measurement of diffusion tensor imaging (DTI) parameters
Externí odkaz:
https://doaj.org/article/a9814b14d8d84911b376ebad056ddde3
Autor:
Yejun Wang, Anneke van der Walt, Mark Paine, Alexander Klistorner, Helmut Butzkueven, Gary F Egan, Trevor J Kilpatrick, Scott C Kolbe
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52291 (2012)
Magnetisation transfer ratio (MTR) can reveal the degree of proton exchange between free water and macromolecules and was suggested to be pathological informative. We aimed to investigate changes in optic nerve MTR over 12 months following acute opti
Externí odkaz:
https://doaj.org/article/0492b19805b54725954a7157c4f8627b
Autor:
Minh N. L. Nguyen, Chao Zhu, Scott C. Kolbe, Helmut Butzkueven, Owen B. White, Joanne Fielding, Trevor J. Kilpatrick, Gary F. Egan, Alexander Klistorner, Anneke van der Walt
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundPredicting long-term visual outcomes and axonal loss following acute optic neuritis (ON) is critical for choosing treatment. Predictive models including all clinical and paraclinical measures of optic nerve dysfunction following ON are lack
Externí odkaz:
https://doaj.org/article/be94646d4bf141bf9437d8c3efe16a30
Autor:
Tracy D. Zhang, Scott C. Kolbe, Leah C. Beauchamp, Ella K. Woodbridge, David I. Finkelstein, Emma L. Burrows
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3026 (2022)
The prodromal phase of Parkinson’s disease (PD) is characterised by many non-motor symptoms, and these have recently been posited to be predictive of later diagnosis. Genetic rodent models can develop non-motor phenotypes, providing tools to identi
Externí odkaz:
https://doaj.org/article/46cbef32bf8f4ea196c95ffeebe7353d
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
The white matter is highly vascularised by the cerebral venous system. In this paper, we describe a unique blood oxygen-level dependent (BOLD) signal within the white matter using functional MRI and spatial independent components analysis. The signal
Externí odkaz:
https://doaj.org/article/4644f880a9194be1b79b9d846ef8d56e
Autor:
Scott C. Kolbe, Warda Syeda, Yasmin Blunck, Rebecca Glarin, Meng Law, Leigh A. Johnston, Jon O. Cleary
Publikováno v:
NeuroImage, Vol 211, Iss , Pp 116609- (2020)
23Na provides the second strongest MR-observable signal in biological tissue and exhibits bi-exponential T2∗ relaxation in micro-environments such as the brain. There is significant interest in developing 23Na biomarkers for neurological diseases t
Externí odkaz:
https://doaj.org/article/0347f78bbab540db83b1be9ea0dcda3f
Autor:
Camille J. Shanahan, Frederique M. C. Boonstra, L. Eduardo Cofré Lizama, Myrte Strik, Bradford A. Moffat, Fary Khan, Trevor J. Kilpatrick, Anneke van der Walt, Mary P. Galea, Scott C. Kolbe
Publikováno v:
Frontiers in Neurology, Vol 8 (2018)
Subtle gait and balance dysfunction is a precursor to loss of mobility in multiple sclerosis (MS). Biomechanical assessments using advanced gait and balance analysis technologies can identify these subtle changes and could be used to predict mobility
Externí odkaz:
https://doaj.org/article/1c080ee168b9426ebc294ec61dadc6d8
Autor:
Myrte Strik, Anand JC Eijlers, Iris Dekker, Tommy AA Broeders, Linda Douw, Joep Killestein, Scott C Kolbe, Jeroen JG Geurts, Menno M Schoonheim
Publikováno v:
Multiple Sclerosis Journal. SAGE Publications Ltd
Strik, M, Eijlers, A J C, Dekker, I, Broeders, T A A, Douw, L, Killestein, J, Kolbe, S C, Geurts, J J G & Schoonheim, M M 2022, ' Sensorimotor network dynamics predict decline in upper and lower limb function in people with multiple sclerosis ', Multiple Sclerosis Journal . https://doi.org/10.1177/13524585221125372
Strik, M, Eijlers, A J C, Dekker, I, Broeders, T A A, Douw, L, Killestein, J, Kolbe, S C, Geurts, J J G & Schoonheim, M M 2022, ' Sensorimotor network dynamics predict decline in upper and lower limb function in people with multiple sclerosis ', Multiple Sclerosis Journal . https://doi.org/10.1177/13524585221125372
Background: Upper and lower limb disabilities are hypothesized to have partially independent underlying (network) disturbances in multiple sclerosis (MS). Objective: This study investigated functional network predictors and longitudinal network chang
Autor:
L Eduardo Cofré Lizama, Myrte Strik, Anneke Van der Walt, Trevor J Kilpatrick, Scott C Kolbe, Mary P Galea
Publikováno v:
Cofré Lizama, L E, Strik, M, van der Walt, A, Kilpatrick, T J, Kolbe, S C & Galea, M P 2022, ' Gait stability reflects motor tracts damage at early stages of multiple sclerosis ', Multiple Sclerosis Journal, vol. 28, no. 11, pp. 1773-1782 . https://doi.org/10.1177/13524585221094464
Multiple Sclerosis Journal, 28(11), 1773-1782. SAGE Publications Ltd
Multiple Sclerosis Journal, 28(11), 1773-1782. SAGE Publications Ltd
Background: Gait in people with multiple sclerosis (PwMS) is affected even when no changes can be observed on clinical examination. A sensitive measure of gait deterioration is stability; however, its correlation with motor tract damage has not yet b
Autor:
Bao N Nguyen, Roger J. Ordidge, Bang V. Bui, Scott C Kolbe, Jon O. Cleary, Bradford A. Moffat, Allison M McKendrick, Rebecca Glarin
Publikováno v:
Magnetic Resonance Imaging Clinics of North America. 29:103-116
Ultrahigh-field (7T) MRI provides improved contrast and a signal-to-noise gain compared with lower magnetic field strengths. Here, we demonstrate feasibility and optimization of anatomic imaging of the eye and orbit using a dedicated commercial multi