Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Scott C, Persohn"'
Cortical cerebrovascular and metabolic perturbations in the 5xFAD mouse model of Alzheimer’s disease
Autor:
Amandine Jullienne, Jenny I. Szu, Ryan Quan, Michelle V. Trinh, Tannoz Norouzi, Brenda P. Noarbe, Amanda A. Bedwell, Kierra Eldridge, Scott C. Persohn, Paul R. Territo, Andre Obenaus
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionThe 5xFAD mouse is a popular model of familial Alzheimer’s disease (AD) that is characterized by early beta-amyloid (Aβ) deposition and cognitive decrements. Despite numerous studies, the 5xFAD mouse has not been comprehensively phenot
Externí odkaz:
https://doaj.org/article/8ec2a97582564be2a7400ac1d5fb9d6d
Autor:
Kristen D. Onos, Sara K. Quinney, David R. Jones, Andrea R. Masters, Ravi Pandey, Kelly J. Keezer, Carla Biesdorf, Ingrid F. Metzger, Jill A. Meyers, Johnathon Peters, Scott C. Persohn, Brian P. McCarthy, Amanda A. Bedwell, Lucas L. Figueiredo, Zackary A. Cope, Michael Sasner, Gareth R. Howell, Harriet M. Williams, Adrian L. Oblak, Bruce T. Lamb, Gregory W. Carter, Stacey J. Sukoff Rizzo, Paul R. Territo
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Hyperexcitability and epileptiform activity are commonplace in Alzheimer's disease (AD) patients and associated with impaired cognitive function. The anti‐seizure drug levetiracetam (LEV) is currently being evaluated in clinic
Externí odkaz:
https://doaj.org/article/6aac82fc377b4d76a3023ef60872d04a
Autor:
Alaina M, Reagan, Karen E, Christensen, Leah C, Graham, Amanda A, Bedwell, Kierra, Eldridge, Rachael, Speedy, Lucas L, Figueiredo, Scott C, Persohn, Teodoro, Bottiglieri, Kwangsik, Nho, Michael, Sasner, Paul R, Territo, Rima, Rozen, Gareth R, Howell
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 42(12)
Vascular contributions to cognitive impairment and dementia (VCID) particularly Alzheimer's disease and related dementias (ADRDs) are increasing; however, mechanisms driving cerebrovascular decline are poorly understood. Methylenetetrahydrofolate red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b777dfaf3b327ed352bb333f71cdea06
https://pubmed.ncbi.nlm.nih.gov/36050860
https://pubmed.ncbi.nlm.nih.gov/36050860
Autor:
Alaina M Reagan, Karen E Christensen, Leah C Graham, Amanda A Bedwell, Kierra Eldridge, Rachael Speedy, Lucas L Figueiredo, Scott C Persohn, Teodoro Bottiglieri, Kwangsik Nho, Michael Sasner, Paul R Territo, Rima Rozen, Gareth R Howell
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 42:2333-2350
Vascular contributions to cognitive impairment and dementia (VCID) particularly Alzheimer’s disease and related dementias (ADRDs) are increasing; however, mechanisms driving cerebrovascular decline are poorly understood. Methylenetetrahydrofolate r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7482d7ee3029e817139cb404a3264cea
https://doi.org/10.1177/0271678x221122644
https://doi.org/10.1177/0271678x221122644
Autor:
Paul R Territo, Sara K Quinney, Andrea R Masters, Katy A Haynes, Zackery A Cope, Gabriela Little, Sean‐Paul Williams, Jill A Meyer, Jonathan Peters, Lucas Figueiredo, Scott C Persohn, Amanda A Bedwell, Kierra Eldridge, Rachael Speedy, Nicholas T. Seyfried, Kristen D Onos, Michael Sasner, Gareth R Howell, Gregory W Carter, Adrian L Oblak, Bruce T Lamb, Stacey J Sukoff Rizzo
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a875fa13472a809c46f785b007ed8c06
https://doi.org/10.1002/alz.064606
https://doi.org/10.1002/alz.064606
Autor:
Brenda P Noarbe, Amandine Jullienne, Rebecca Silvola, Amanda A Bedwell, Kierra Eldridge, Rachael Speedy, Scott C Persohn, Paul R Territo, Andre Obenaus, MODEL AD
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0984ea5d56b448a9cf15fa177e89de96
https://doi.org/10.1002/alz.062637
https://doi.org/10.1002/alz.062637
Autor:
Peter Bor‐Chian Lin, Scott C Persohn, Amanda A Bedwell, Lei Jiang, Kierra Eldridge, Rachael Speedy, Kevin P Kotredes, Ravi S Pandey, Harriet M Williams, Adrian L Oblak, Michael Sasner, Gareth R Howell, Gregory W Carter, Bruce T Lamb, Paul R Territo
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5a875d7f175ddacccdc7889f30687bf
https://doi.org/10.1002/alz.063682
https://doi.org/10.1002/alz.063682
Autor:
Adrian L. Oblak, Kevin P. Kotredes, Ravi Pandey, Alaina M. Reagan, Cynthia Ingraham, Bridget Perkins, Chris Lloyd, Deborah Baker, Peter B. Lin, Disha M. Soni, Andy Tsai, Scott C. Persohn, Amanda A Bedwell, Kierra Eldridge, Rachael Speedy, Jill A. Meyers, Johnathon Peters, Lucas L. Figueiredo, Michael Sasner, Paul R. Territo, Stacey J. Sukoff Rizzo, Gregory W. Carter, Bruce T. Lamb, Gareth R. Howell
Obesity is recognized as a significant risk factor for Alzheimer’s disease (AD). Studies have supported the notion that obesity accelerates AD-related pathophysiology in mouse models of AD. The majority of studies to date have focused on the use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::735dee5cf96ea9e700f565fdcad316cd
https://doi.org/10.1101/2022.02.11.480032
https://doi.org/10.1101/2022.02.11.480032
Autor:
Alaina M. Reagan, Karen E. Christensen, Leah C. Graham, Amanda A. Bedwell, Kierra Eldridge, Rachael Speedy, Lucas L. Figueiredo, Scott C. Persohn, Teodoro Bottiglieri, Michael Sasner, Paul R. Territo, Rima Rozen, Gareth R. Howell
Vascular contributions to cognitive impairment and dementia (VCID) particularly Alzheimer’s disease and related dementias (ADRDs) are increasing; however, mechanisms driving cerebrovascular decline are poorly understood. Methylenetetrahydrofolate r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a495d9decd9314e5a8bd0cf4d7825317
https://doi.org/10.1101/2021.12.16.472805
https://doi.org/10.1101/2021.12.16.472805
Autor:
Michael Sasner, Amanda A. Bedwell, Kierra Eldridge, Bruce T. Lamb, Gregory W. Carter, Adrian L. Oblak, Kevin P. Kotredes, Ravi S. Pandey, Rachael Speedy, Scott C. Persohn, Paul R. Territo, Peter Bor-Chian Lin, Gareth R. Howell
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd8d3cb50f7a393072733c222e413be
https://doi.org/10.1002/alz.041531
https://doi.org/10.1002/alz.041531