Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Scott Baskerville"'
Autor:
Mathew Miller, Oscar Alvizo, Chinping Chng, Stephan Jenne, Melissa Mayo, Arpan Mukherjee, Stuart Sundseth, Avinash Chintala, Jonathan Penfield, James Riggins, Xiyun Zhang, Antoinette Sero, Justin Dassie, Neil Leatherbury, Scott Baskerville, Gjalt Huisman
Messenger RNA (mRNA) therapies have recently gained tremendous traction with the approval of mRNA vaccines for the prevention of SARS-CoV-2 infection. However, manufacturing challenges have complicated large scale mRNA production, which is necessary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fbccc1b28684e06bb5292810d6cd422
https://doi.org/10.1101/2022.09.01.506264
https://doi.org/10.1101/2022.09.01.506264
Autor:
Marc Rippen, Scott Baskerville, M. Cecilia Lansang, Vignesh Balasubramanian, James Bena, Ryan Bailey, Keira McCarthy, Lauren Buehler
Publikováno v:
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 28(2)
The Alertgy noninvasive continuous glucose monitor (ANICGM) is a novel wristband device that reports glucose levels without entailing skin puncture. This study evaluated the performance of the ANICGM compared to a Food and Drug Administration-approve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f1f1474a428f1996c6a631f9ab4ddd
https://pubmed.ncbi.nlm.nih.gov/34600130
https://pubmed.ncbi.nlm.nih.gov/34600130
Autor:
Annaleen Vermeulen, Devin Leake, Jon Karpilow, Anastasia Khvorova, Barbara Robertson, William Marshall, Andrew B. Dalby, Scott Baskerville
Publikováno v:
RNA. 13:723-730
While microRNAs (miRNAs) are recognized as playing a critical role in regulating eukaryotic gene expression, both the mechanism by which these small, noncoding RNAs function and the genes they target remain elusive. Previous studies have shown that s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8bed9de9fe79581004d141c0e69367
https://doi.org/10.1261/rna.448107
https://doi.org/10.1261/rna.448107
Publikováno v:
Proceedings of the National Academy of Sciences. 103:8721-8726
Since their discovery as key regulators of early animal development, microRNAs now are recognized as widespread regulators of gene expression. Despite their abundance, little is known regarding the regulation of microRNA biogenesis. We show that thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a4b2bc58d1bb5555628533cd523e5d
https://doi.org/10.1073/pnas.0602831103
https://doi.org/10.1073/pnas.0602831103
Autor:
Scott Baskerville, David P. Bartel
Publikováno v:
RNA. 11:241-247
MicroRNAs (miRNAs) are short endogenous RNAs known to post-transcriptionally repress gene expression in animals and plants. A microarray profiling survey revealed the expression patterns of 175 human miRNAs across 24 different human organs. Our resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f01ac59351e1e937f35be10273aae2c
https://doi.org/10.1261/rna.7240905
https://doi.org/10.1261/rna.7240905
Autor:
Scott Baskerville, David P. Bartel
Publikováno v:
Proceedings of the National Academy of Sciences. 99:9154-9159
We have used a combination of in vitro selection and rational design to generate ribozymes that form a stable phosphoamide bond between the 5′ terminus of an RNA and a specific polypeptide. This reaction differs from that of previously identified r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d906e758cd75752e45c1b89090c06fd1
https://doi.org/10.1073/pnas.142153799
https://doi.org/10.1073/pnas.142153799
Publikováno v:
Molecular Diversity. 1:69-78
In vitro selection, or SELEX, has been used both to characterize the interaction of natural nucleic acids with proteins and to generate novel nucleic acid-binding species, or aptamers. Although numerous reports have demonstrated the power of the tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44bcb93704f69af6adfa594370609be
https://doi.org/10.1007/bf01715810
https://doi.org/10.1007/bf01715810
Autor:
Yangming Wang, Robert Blelloch, Lauren Baehner, Archana Shenoy, Scott Baskerville, Joshua E. Babiarz
Publikováno v:
Nature genetics
Dgcr8 knockout embryonic stem (ES) cells lack microprocessor activity and hence all canonical microRNAs (miRNAs). These cells proliferate slowly and accumulate in G1 phase of the cell cycle1. Here, by screening a comprehensive library of individual m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1add8edcc089ed3761bc5a3667365343
https://pubmed.ncbi.nlm.nih.gov/18978791
https://pubmed.ncbi.nlm.nih.gov/18978791
Autor:
Elena Maksimova, Angela Reynolds, Anastasia Khvorova, Jon Karpilow, Amanda Birmingham, Yuriy Fedorov, Emily M. Anderson, Devin Leake, Scott Baskerville
Pairing between the hexamer seed region of a small interfering RNA (siRNA) guide strand (nucleotides 2–7) and complementary sequences in the 3′ UTR of mature transcripts has been implicated as an important element in off-target gene regulation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a22440df6d24bc75c0765df324633d7
https://europepmc.org/articles/PMC2327361/
https://europepmc.org/articles/PMC2327361/
Autor:
Scott Baskerville
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7af4064ee39acf2295f3c1797f96baa2
https://doi.org/10.1096/fasebj.22.1_supplement.535.3
https://doi.org/10.1096/fasebj.22.1_supplement.535.3