Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Scott B. Meikrantz"'
Autor:
David A. Quincy, Nicholas R. Natale, Victoria Hulubei, John I. McKenna, Tina Houle, Scott A. Steiger, Mark E. Rogers, Scott B. Meikrantz
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:6613-6620
The 4-isoxazolyl-dihydropyridines (IDHPs) exhibit inhibition of the multidrug-resistance transporter (MDR-1), and exhibit an SAR distinct from their activity at voltage gated calcium channels (VGCC). Among the four most active IDHPs, three were branc
Publikováno v:
Synthetic Communications. 24:399-407
Two carbon homologation of isoxazole-4-carbinols was performed by reaction of lithio-2,4,4-trimethyl-δ2-oxazoline 1 with 4-chloromethyl-isoxazole 2, followed by trans-esterification and reduction to the isoxazole-4-propanols 5a and b. Alternatively,
Publikováno v:
ChemInform. 25
Autor:
David J. Triggle, Nicholas R. Natale, Yong Wha Kwon, Timothy L. Hubler, Scott B. Meikrantz, Thomas E. Bitterwolf
Publikováno v:
Journal of medicinal chemistry. 35(6)