Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Scott B. Cohen"'
Autor:
Basma M. Klump, Gloria I. Perez, Eric M. Patrick, Kate Adams-Boone, Scott B. Cohen, Li Han, Kefei Yu, Jens C. Schmidt
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112577- (2023)
Summary: Localization of a variety of RNAs to non-membrane-bound cellular compartments such as nucleoli and Cajal bodies is critical for their stability and function. The molecular mechanisms that underly the recruitment and exclusion of RNAs from th
Externí odkaz:
https://doaj.org/article/f4ed1d519dc94c5390ee2c08bbcc1031
Autor:
Henrik Spåhr, Tiongsun Chia, James P. Lingford, Stefan J. Siira, Scott B. Cohen, Aleksandra Filipovska, Oliver Rackham
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Pentatricopeptide repeat proteins bind single-stranded RNA and have been used to study ssRNA biology. Here the authors co-opt these proteins to target ssDNA and demonstrate specific binding of telomere sequences, the structural basis for ssDNA wrappi
Externí odkaz:
https://doaj.org/article/a5f04e9e85b34966956baa59fefb1987
Autor:
Bishnu P Paudel, Aaron Lavel Moye, Hala Abou Assi, Roberto El-Khoury, Scott B Cohen, Jessica K Holien, Monica L Birrento, Siritron Samosorn, Kamthorn Intharapichai, Christopher G Tomlinson, Marie-Paule Teulade-Fichou, Carlos González, Jennifer L Beck, Masad J Damha, Antoine M van Oijen, Tracy M Bryan
Publikováno v:
eLife, Vol 9 (2020)
Telomeric G-quadruplexes (G4) were long believed to form a protective structure at telomeres, preventing their extension by the ribonucleoprotein telomerase. Contrary to this belief, we have previously demonstrated that parallel-stranded conformation
Externí odkaz:
https://doaj.org/article/44d7e6c98c07413a81971b3cbc70d688
Autor:
Scott B. Cohen, Tracy M. Bryan
Publikováno v:
Handbook of Chemical Biology of Nucleic Acids ISBN: 9789811613135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78d7bd57a7f1d878e16b5570839cf146
https://doi.org/10.1007/978-981-16-1313-5_104-1
https://doi.org/10.1007/978-981-16-1313-5_104-1
Autor:
Tracy M. Bryan, Scott B. Cohen
Publikováno v:
Handbook of Chemical Biology of Nucleic Acids ISBN: 9789811613135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2875b303d9f61c8a16ea66dab596493f
https://doi.org/10.1007/978-981-16-1313-5_47-1
https://doi.org/10.1007/978-981-16-1313-5_47-1
Autor:
Ritu Sachdeva, Anne Marie Valente, Aimee K. Armstrong, Stephen C. Cook, B. Kelly Han, Leo Lopez, George K. Lui, Sarah S. Pickard, Andrew J. Powell, Nicole M. Bhave, Jeanne M. Baffa, Puja Banka, Scott B. Cohen, Julie S. Glickstein, Joshua P. Kanter, Ronald J. Kanter, Yuli Y. Kim, Alaina K. Kipps, Larry A. Latson, Jeannette P. Lin, David A. Parra, Fred H. Rodriguez, Elizabeth V. Saarel, Shubhika Srivastava, Elizabeth A. Stephenson, Karen K. Stout, Ali N. Zaidi, Ty J. Gluckman, Niti R. Aggarwal, Gregory J. Dehmer, Olivia N. Gilbert, Dharam J. Kumbhani, Andrea L. Price, David E. Winchester, Martha Gulati, John U. Doherty, Stacie L. Daugherty, Larry S. Dean, Milind Y. Desai, Linda D. Gillam, Praveen Mehrotra
Publikováno v:
Journal of the American Society of Echocardiography. 33:e1-e48
Publikováno v:
ACS Chem Biol
Telomerase is a ribonuceloprotein complex responsible for maintaining telomeres and protecting chromosomal integrity. The human telomerase reverse transcriptase (hTERT) is expressed in ~90% of cancer cells where it confers the capacity for limitless
Autor:
Aram Niaz, Jia Truong, Annabel Manoleras, Lucy C. Fox, Piers Blombery, Raja S. Vasireddy, Hilda A. Pickett, Julie A. Curtin, Pasquale M. Barbaro, Jonathan Rodgers, John Roy, Lisa G. Riley, Jessica K. Holien, Scott B. Cohen, Tracy M. Bryan
Publikováno v:
Blood advances. 6(12)
Telomere biology disorders (TBDs) are a spectrum of multisystem inherited disorders characterized by bone marrow failure, resulting from mutations in the genes encoding telomerase or other proteins involved in maintaining telomere length and integrit
Autor:
Yue Liu, Rick C. Betori, Joanna Pagacz, Grant B. Frost, Elena V. Efimova, Ding Wu, Donald J. Wolfgeher, Tracy M. Bryan, Scott B. Cohen, Karl A. Scheidt, Stephen J. Kron
Publikováno v:
Cell Chemical Biology. 29:1517-1531.e7
Beyond synthesizing telomere repeats, the telomerase reverse transcriptase (TERT) also serves multiple other roles supporting cancer growth. Blocking telomerase to drive telomere erosion appears impractical, but TERT's non-canonical activities have y
Autor:
Kefei Yu, Jens C. Schmidt, Kate Adams-Boone, Scott B. Cohen, Gloria I. Perez, Basma S. Al-Masraf, Li Han
Localization of a wide variety of RNAs to non-membrane bound cellular compartments such as nucleoli, Cajal bodies, and stress-granules is critical for their function and stability. The molecular mechanisms that underly the recruitment and exclusion o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51f6d7bc048487b57a3fc3a595051ac9
https://doi.org/10.1101/2021.05.27.445986
https://doi.org/10.1101/2021.05.27.445986