Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Scott B Thompson"'
Autor:
Scott B Thompson, Adam M Sandor, Victor Lui, Jeffrey W Chung, Monique M Waldman, Robert A Long, Miriam L Estin, Jennifer L Matsuda, Rachel S Friedman, Jordan Jacobelli
Publikováno v:
eLife, Vol 9 (2020)
Lymphocyte migration is essential for the function of the adaptive immune system, and regulation of T cell entry into tissues is an effective therapy in autoimmune diseases. Little is known about the specific role of cytoskeletal effectors that media
Externí odkaz:
https://doaj.org/article/05848d0787a543cab416fc0649eb8077
Autor:
Ashton L. Sigler, Scott B. Thompson, Logan Ellwood-Digel, Adithan Kandasamy, Mary J. Michaels, Dean Thumkeo, Shuh Narumiya, Juan C. Del Alamo, Jordan Jacobelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Lymphocyte trafficking and migration through tissues is critical for adaptive immune function and, to perform their roles, T cells must be able to navigate through diverse tissue environments that present a range of mechanical challenges. T cells pre
Externí odkaz:
https://doaj.org/article/8d8a242143d24c529f8431db63d56272
Autor:
Meng-Han Wu, Felipe Valenca-Pereira, Francesca Cendali, Emily L. Giddings, Catherine Pham-Danis, Michael C. Yarnell, Amanda J. Novak, Tonya M. Brunetti, Scott B. Thompson, Jorge Henao-Mejia, Richard A. Flavell, Angelo D’Alessandro, M. Eric Kohler, Mercedes Rincon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Mitochondrial respiration is essential for the survival and function of T cells used in adoptive cellular therapies. However, strategies that specifically enhance mitochondrial respiration to promote T cell function remain limited. Here, we
Externí odkaz:
https://doaj.org/article/d0884f5a1b81480bad4290e7a5d667fa
Autor:
Daria L. Ivanova, Scott B. Thompson, Jared Klarquist, Michael G. Harbell, Augustus M. Kilgore, Erika L. Lasda, Jay R. Hesselberth, Christopher A. Hunter, Ross M. Kedl
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112911- (2023)
Summary: T-bet and FOXO1 are transcription factors canonically associated with effector and memory T cell fates, respectively. During an infectious response, these factors direct the development of CD8+ T cell fates, where T-bet deficiency leads to a
Externí odkaz:
https://doaj.org/article/5b185e3c9b34469baf940c2d2c73e409
Autor:
Jared Klarquist, Eric W. Cross, Scott B. Thompson, Benjamin Willett, Daniel L. Aldridge, Alayna K. Caffrey-Carr, Zhenming Xu, Christopher A. Hunter, Andrew Getahun, Ross M. Kedl
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109591- (2021)
Summary: The relationship between B cells and CD4 T cells has been carefully studied, revealing a collaborative effort in which B cells promote the activation, differentiation, and expansion of CD4 T cells while the so-called “helper” cells provi
Externí odkaz:
https://doaj.org/article/8dbc250170514849a5df5a00f6540f40
Autor:
Scott B. Thompson, Eric J. Wigton, Sai Harsha Krovi, Jeffrey W. Chung, Robert A. Long, Jordan Jacobelli
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Leukemias typically arise in the bone marrow and then spread to the blood and into other tissues. To disseminate into tissues, leukemia cells migrate into the blood stream and then exit the circulation by migrating across vascular endothelial barrier
Externí odkaz:
https://doaj.org/article/afc9c01cb6db49a2b593407fb3cd88a6
Autor:
Anas Younes, Roger Smith, Sanjeeva P. Reddy, Venkatraman E. Seshan, Louis Denis, Sandeep Kumar Gupta, Mariana Da Silva Ferreira, Elisa de Stanchina, Scott B Thompson, Andrea Knezevic, Ana Portelinha, Zahra Asgari
Publikováno v:
Cell Reports Medicine
Summary Inhibition of the extracellular signal-regulated kinases ERK1 and ERK2 (ERK1/2) offers a promising therapeutic strategy in cancers harboring activated RAS/RAF/MEK/ERK signaling pathways. Here, we describe an orally bioavailable and selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d73b4c01a75f283a209d14c9c6d87ea
http://europepmc.org/articles/PMC8324497
http://europepmc.org/articles/PMC8324497
Publikováno v:
The FEBS journalReferences. 289(20)
During their life span, T cells are tasked with patrolling the body for potential pathogens. To do so, T cells migrate through numerous distinct anatomical sites and tissue environments with different biophysical characteristics. To migrate through t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5096655ee0c59d7f826bab57b9dafa0
https://pubmed.ncbi.nlm.nih.gov/34273243
https://pubmed.ncbi.nlm.nih.gov/34273243
Autor:
Ross M. Kedl, Benjamin Willett, Zheming Xu, Jared Klarquist, Christopher A. Hunter, Andrew Getahun, Scott B. Thompson, Daniel L. Aldridge, Alayna Caffrey-Carr, Eric W. Cross
Publikováno v:
SSRN Electronic Journal.
The close relationship between B cells and CD4 T cells has been carefully studied, revealing a collaborative effort, where B cells promote the activation, differentiation, and expansion of CD4 T cells, while the so-called “helper” cells provide s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dc080f22e6e105296868d49df84e17a
https://doi.org/10.2139/ssrn.3844714
https://doi.org/10.2139/ssrn.3844714
Autor:
Scott B Thompson, Adam M. Sandor, Jeffrey W Chung, Miriam L Estin, Jennifer L. Matsuda, Rachel S. Friedman, Victor Lui, Jordan Jacobelli, Robert A Long, Monique M Waldman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::339c06ee5882c38e26fc80fee63ae01e
https://doi.org/10.7554/elife.58046.sa2
https://doi.org/10.7554/elife.58046.sa2
