Zobrazeno 1 - 10
of 364
pro vyhledávání: '"Scott B Snapper"'
Autor:
Naresh S Redhu, Vasudevan Bakthavatchalu, Evan A Conaway, Dror S Shouval, Amy Tsou, Jeremy A Goettel, Amlan Biswas, Chuanwu Wang, Michael Field, Werner Muller, Andre Bleich, Ning Li, Georg K Gerber, Lynn Bry, James G Fox, Scott B Snapper, Bruce H Horwitz
Publikováno v:
eLife, Vol 6 (2017)
Infants with defects in the interleukin 10 receptor (IL10R) develop very early onset inflammatory bowel disease. Whether IL10R regulates lamina propria macrophage function during infant development in mice and whether macrophage-intrinsic IL10R signa
Externí odkaz:
https://doaj.org/article/724f8523dc5d4a638ab2b5308f22edd9
Autor:
Xiang Xiao, Dolores D Mruk, Elizabeth I Tang, R'ada Massarwa, Ka Wai Mok, Nan Li, Chris K C Wong, Will M Lee, Scott B Snapper, Ben-Zion Shilo, Eyal D Schejter, C Yan Cheng
Publikováno v:
PLoS Genetics, Vol 10, Iss 6, p e1004447 (2014)
During spermatogenesis, the blood-testis barrier (BTB) segregates the adluminal (apical) and basal compartments in the seminiferous epithelium, thereby creating a privileged adluminal environment that allows post-meiotic spermatid development to proc
Externí odkaz:
https://doaj.org/article/8b94d083f01a4d2a997accb398665ee3
Autor:
Chaohong Liu, Xiaoming Bai, Junfeng Wu, Shruti Sharma, Arpita Upadhyaya, Carin I M Dahlberg, Lisa S Westerberg, Scott B Snapper, Xiaodong Zhao, Wenxia Song
Publikováno v:
PLoS Biology, Vol 11, Iss 11, p e1001704 (2013)
Negative regulation of receptor signaling is essential for controlling cell activation and differentiation. In B-lymphocytes, the down-regulation of B-cell antigen receptor (BCR) signaling is critical for suppressing the activation of self-reactive B
Externí odkaz:
https://doaj.org/article/115b27f716764bbca176b4121b4bc601
Autor:
Naamah L Zitomersky, Benjamin J Atkinson, Sarah W Franklin, Paul D Mitchell, Scott B Snapper, Laurie E Comstock, Athos Bousvaros
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e63686 (2013)
There is extensive evidence implicating the intestinal microbiota in inflammatory bowel disease [IBD], but no microbial agent has been identified as a sole causative agent. Bacteroidales are numerically dominant intestinal organisms that associate wi
Externí odkaz:
https://doaj.org/article/dd7c33b2592d446091bd9be0c53ad9f8
Autor:
Didier Vingadassalom, Kenneth G Campellone, Michael J Brady, Brian Skehan, Scott E Battle, Douglas Robbins, Archana Kapoor, Gail Hecht, Scott B Snapper, John M Leong
Publikováno v:
PLoS Pathogens, Vol 6, Iss 8, p e1001056 (2010)
Upon infection of mammalian cells, enterohemorrhagic E. coli (EHEC) O157:H7 utilizes a type III secretion system to translocate the effectors Tir and EspF(U) (aka TccP) that trigger the formation of F-actin-rich 'pedestals' beneath bound bacteria. Es
Externí odkaz:
https://doaj.org/article/ef15d42bff434646ac26668f7b7550c6
Autor:
Bin Bao, Youyuan Wang, Pavl Boudreau, Xinyang Song, Meng Wu, Xi Chen, Izabel Patik, Ying Tang, Jodie Ouahed, Amit Ringel, Jared Barends, Chuan Wu, Emily Balskus, Jay Thiagarajah, Jian Liu, Michael R. Wessels, Wayne Isaac Lencer, Dennis L. Kasper, Dingding An, Bruce Harold Horwitz, Scott B. Snapper
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 2, Pp 101350- (2024)
Background & Aims: Gut bacterial sphingolipids, primarily produced by Bacteroidetes, have dual roles as bacterial virulence factors and regulators of the host mucosal immune system, including regulatory T cells and invariant natural killer T cells. P
Externí odkaz:
https://doaj.org/article/ebe59fd22bdd4d17a31e6bcf11e820ec
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/bb32d72ca4d44772be2a3318ea8a86c7
Autor:
Mutaz Sultan, Mohammad Adawi, Nitzan Kol, Blake McCourt, Ihda Adawi, Liran Baram, Noa Tal, Lael Werner, Atar Lev, Scott B. Snapper, Ortal Barel, Liza Konnikova, Raz Somech, Dror S. Shouval
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
PurposeReceptor-interacting serine/threonine-protein kinase 1 (RIPK1) is an important regulator of necroptosis and inflammatory responses. We present the clinical features, genetic analysis and immune work-up of two patients with infantile-onset infl
Externí odkaz:
https://doaj.org/article/9d62de14171e45ad88380c878ee90f4b
Autor:
Lauren V. Collen, Carlos Andres Salgado, Bin Bao, Erin Janssen, Dascha Weir, Jeffrey Goldsmith, Alan Leichtner, Nasim Sabery Khavari, Yael Gernez, Scott B. Snapper
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Primary immunodeficiency may present with treatment-refractory enteropathy. We present two patients with celiac/celiac-like disease diagnosed in early childhood and refractory to the gluten-free diet. One patient had features of multi-system autoimmu
Externí odkaz:
https://doaj.org/article/45bd3438714c488d8cc705c26a877a71
Autor:
Eva Gonçalves Serra, Tobias Schwerd, Loukas Moutsianas, Athena Cavounidis, Laura Fachal, Sumeet Pandey, Jochen Kammermeier, Nicholas M. Croft, Carsten Posovszky, Astor Rodrigues, Richard K. Russell, Farah Barakat, Marcus K. H. Auth, Robert Heuschkel, Matthias Zilbauer, Krzysztof Fyderek, Christian Braegger, Simon P. Travis, Jack Satsangi, Miles Parkes, Nikhil Thapar, Helen Ferry, Julie C. Matte, Kimberly C. Gilmour, Andrzej Wedrychowicz, Peter Sullivan, Carmel Moore, Jennifer Sambrook, Willem Ouwehand, David Roberts, John Danesh, Toni A. Baeumler, Tudor A. Fulga, Eli M Carrami, Ahmed Ahmed, Rachel Wilson, Jeffrey C. Barrett, Abdul Elkadri, Anne M. Griffiths, COLORS in IBD group investigators, Oxford IBD cohort study investigators, INTERVAL Study, Swiss IBD cohort investigators, UK IBD Genetics Consortium, NIDDK IBD Genetics Consortium, Scott B. Snapper, Neil Shah, Aleixo M. Muise, David C. Wilson, Holm H. Uhlig, Carl A. Anderson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/5c86d325bfef42dd9f9c9aa2ea68a8c9