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pro vyhledávání: '"Scott B Marrus"'
Autor:
Jacob I Laughner, Scott B Marrus, Erik R Zellmer, Carla J Weinheimer, Matthew R MacEwan, Sophia X Cui, Jeanne M Nerbonne, Igor R Efimov
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76291 (2013)
Animal models have become a popular platform for the investigation of the molecular and systemic mechanisms of pathological cardiovascular physiology. Chronic pacing studies with implantable pacemakers in large animals have led to useful models of he
Externí odkaz:
https://doaj.org/article/8de29fd18ad04bef9ccb1fdbc7c49032
Publikováno v:
Circulation: Arrhythmia and Electrophysiology. 5:773-781
Background— Cardiac memory refers to the observation that altered cardiac electrical activation results in repolarization changes that persist after the restoration of a normal activation pattern. Animal studies, however, have yielded disparate con
Autor:
Scott B. Marrus, Aaron DiAntonio
Publikováno v:
Current Biology. 14:924-931
Background: The localization of glutamate receptors is essential for the formation and plasticity of excitatory synapses. These receptors cluster opposite neurotransmitter release sites of glutamatergic neurons, but these release sites have heterogen
Publikováno v:
The Journal of Neuroscience. 24:1406-1415
The subunit composition of postsynaptic neurotransmitter receptors is a key determinant of synaptic physiology. Two glutamate receptor subunits,Drosophilaglutamate receptor IIA (DGluRIIA) and DGluRIIB, are expressed at theDrosophilaneuromuscular junc
Autor:
Steven Springer, Jeanne M. Nerbonne, Anna Zhang, Edward J. Dranoff, Scott B. Marrus, Rita Martinez, Rebecca H. Mellor, Evelyn M. Kanter, Kathryn A. Yamada
Publikováno v:
Circulation. 130
Abnormalities of a key repolarizing cardiac potassium current, the fast transient outward potassium current, I to,f , are associated with both heart failure and congenital arrhythmia syndromes. However, the precise role of I to,f in shaping action po
Autor:
Carla J. Weinheimer, Scott B. Marrus, Sophia X. Cui, Jeanne M. Nerbonne, Igor R. Efimov, Jacob I. Laughner, Matthew R. MacEwan, Erik R. Zellmer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 10, p e76291 (2013)
PLoS ONE, Vol 8, Iss 10, p e76291 (2013)
Animal models have become a popular platform for the investigation of the molecular and systemic mechanisms of pathological cardiovascular physiology. Chronic pacing studies with implantable pacemakers in large animals have led to useful models of he
Autor:
M. Le, Michael Rosbash, Julia A. Yaglom, Scott B. Marrus, Ravi Allada, Hongkui Zeng, J. Rutila, M. Dembinska, W.Q. Guo, Z. Qian
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 61:265-278
Publikováno v:
Channels (Austin, Tex.). 5(6)
Andersen-Tawil syndrome is characterized by periodic paralysis, ventricular ectopy, and dysmorphic features. Approximately 60% of patients exhibit loss-of-function mutations in KCNJ2, which encodes the inwardly rectifying K(+) channel pore forming su
Autor:
Scott B. Marrus, Jeanne M. Nerbonne
Publikováno v:
Channels (Austin, Tex.). 2(2)
Ion channels play a central role in the normal electro-mechanical functioning of the heart and are implicated in a variety of disease processes. In response to electrical or mechanical perturbations, cardiac myocytes exhibit remarkable changes in the
Autor:
Scott B. Marrus, Aaron DiAntonio
Publikováno v:
Journal of neurobiology. 63(1)
Fidelity of synaptic transmission is essential at the neuromuscular junction (NMJ). To ensure that transmission does not fail, vertebrate motoneurons often release more neurotransmitter than is required for muscle contraction. This safety factor allo