Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Scott B Drutman"'
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11144 (2010)
Immunotherapeutic strategies to stimulate anti-tumor immunity are promising approaches for cancer treatment. A major barrier to their success is the immunosuppressive microenvironment of tumors, which inhibits the functions of endogenous dendritic ce
Externí odkaz:
https://doaj.org/article/46912c75a9b54ebc874d3c405e09a90d
Autor:
Cassandra R. Harapas, Kim S. Robinson, Kenneth Lay, Jasmine Wong, Ricardo Moreno Traspas, Nasrin Nabavizadeh, Annick Rass-Rothschild, Bertrand Boisson, Scott B. Drutman, Pawat Laohamonthonkul, Devon Bonner, Jingwei Rachel Xiong, Mark D. Gorrell, Sophia Davidson, Chien-Hsiung Yu, Mark D. Fleming, Jonas Gudera, Jerry Stein, Miriam Ben-Harosh, Emily Groopman, Akiko Shimamura, Hannah Tamary, Hülya Kayserili, Nevin Hatipoğlu, Jean-Laurent Casanova, Jonathan A. Bernstein, Franklin L. Zhong, Seth L. Masters, Bruno Reversade
Publikováno v:
Sci Immunol
Dipeptidyl peptidase 9 (DPP9) is a direct inhibitor of NLRP1, but how it affects inflammasome regulation in vivo is not yet established. Here, we report three families with immune-associated defects, poor growth, pancytopenia, and skin pigmentation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ee3ba9502fc466d9b6603e4fdcf190
https://pubmed.ncbi.nlm.nih.gov/36112693
https://pubmed.ncbi.nlm.nih.gov/36112693
Autor:
Bharat Burman, Scott B. Drutman, Matthew G. Fury, Richard J. Wong, Nora Katabi, Alan L. Ho, David G. Pfister
Publikováno v:
Oral Oncol
OBJECTIVES: Ribavirin inhibits eukaryotic translation initiation factor 4E (eIF4E), thereby decreasing cap-dependent translation. In this two-part study, we assessed the pharmacodynamic effects and therapeutic potential of ribavirin in human papillom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e70076c06a863d6a8933d903ed53c7
https://europepmc.org/articles/PMC9788648/
https://europepmc.org/articles/PMC9788648/
Autor:
Scott B, Drutman, Filomeen, Haerynck, Franklin L, Zhong, David, Hum, Nicholas J, Hernandez, Serkan, Belkaya, Franck, Rapaport, Sarah Jill, de Jong, David, Creytens, Simon J, Tavernier, Katrien, Bonte, Sofie, De Schepper, Jutte, van der Werff Ten Bosch, Lazaro, Lorenzo-Diaz, Andy, Wullaert, Xavier, Bossuyt, Gérard, Orth, Vincent R, Bonagura, Vivien, Béziat, Laurent, Abel, Emmanuelle, Jouanguy, Bruno, Reversade, Jean-Laurent, Casanova
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(38)
Juvenile-onset recurrent respiratory papillomatosis (JRRP) is a rare and debilitating childhood disease that presents with recurrent growth of papillomas in the upper airway. Two common human papillomaviruses (HPVs), HPV-6 and -11, are implicated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c51cafed86ca33ad8ec950402dfb5cdf
https://pubmed.ncbi.nlm.nih.gov/31484767
https://pubmed.ncbi.nlm.nih.gov/31484767
Publikováno v:
The Journal of Immunology. 188:3603-3610
Monocytes can differentiate into various cell types with unique specializations depending on their environment. Under certain inflammatory conditions, monocytes upregulate expression of the dendritic cell marker CD11c together with MHC and costimulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197accb345366b1e82e011b651cad3b5
https://doi.org/10.4049/jimmunol.1102741
https://doi.org/10.4049/jimmunol.1102741
Autor:
Scott B. Drutman, Miguel Sanchez
Publikováno v:
Expert Review of Dermatology. 7:93-106
The interactions between microbial pathogens and human skin are complex. Skin disease can be caused by injury from invasion of pathogens, microorganism-targeted immune response, oncogenic cellular transformation and inflammatory responses directed at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c948492ababe489bceb41064f3fe7a0e
https://doi.org/10.1586/edm.11.86
https://doi.org/10.1586/edm.11.86
Autor:
E. Sergio Trombetta, Scott B. Drutman
Dendritic cell (DC) maturation is critical for the regulation of T cell responses. The downregulation of endocytosis on maturation is considered a key adaptation that dissociates prior Ag capture by DCs from subsequent T cell engagement. To study the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41af90aa9888e0da23bc1939b78718ae
https://europepmc.org/articles/PMC2928255/
https://europepmc.org/articles/PMC2928255/
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11144 (2010)
PLoS ONE, Vol 5, Iss 6, p e11144 (2010)
Background: Immunotherapeutic strategies to stimulate anti-tumor immunity are promising approaches for cancer treatment. A major barrier to their success is the immunosuppressive microenvironment of tumors, which inhibits the functions of endogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a96bc1277023a138756fad8a7f0eea
http://europepmc.org/articles/PMC2886840
http://europepmc.org/articles/PMC2886840