Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Scott B Biering"'
Autor:
Marcus P Wong, Evan Y W Juan, Felix Pahmeier, Sai S Chelluri, Phoebe Wang, Bryan Castillo-Rojas, Sophie F Blanc, Scott B Biering, Russell E Vance, Eva Harris
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012167 (2024)
Dengue virus (DENV) is a medically important flavivirus causing an estimated 50-100 million dengue cases annually, some of whom progress to severe disease. DENV non-structural protein 1 (NS1) is secreted from infected cells and has been implicated as
Externí odkaz:
https://doaj.org/article/68d4af973a844bef8593e012140fc8f3
Autor:
Jin Wei, Mia Madel Alfajaro, Wesley L Cai, Vincent R Graziano, Madison S Strine, Renata B Filler, Scott B Biering, Sylvia A Sarnik, Sonam Patel, Bridget L Menasche, Susan R Compton, Silvana Konermann, Patrick D Hsu, Robert C Orchard, Qin Yan, Craig B Wilen
Publikováno v:
PLoS Pathogens, Vol 19, Iss 7, p e1011351 (2023)
Identification of host determinants of coronavirus infection informs mechanisms of pathogenesis and may provide novel therapeutic targets. Here, we demonstrate that the histone demethylase KDM6A promotes infection of diverse coronaviruses, including
Externí odkaz:
https://doaj.org/article/96107a75fb7e477fb76c01fbddef0ecf
DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.
Autor:
Madison S Strine, Wesley L Cai, Jin Wei, Mia Madel Alfajaro, Renata B Filler, Scott B Biering, Sylvia Sarnik, Ryan D Chow, Ajinkya Patil, Kasey S Cervantes, Clayton K Collings, Peter C DeWeirdt, Ruth E Hanna, Kevin Schofield, Christopher Hulme, Silvana Konermann, John G Doench, Patrick D Hsu, Cigall Kadoch, Qin Yan, Craig B Wilen
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002097 (2023)
Identifying host genes essential for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has the potential to reveal novel drug targets and further our understanding of Coronavirus Disease 2019 (COVID-19). We previously performed a genome-wi
Externí odkaz:
https://doaj.org/article/c10dd58b10dd439eb9610eccf28fbb91
Autor:
Guillaume R Golovkine, Allison W Roberts, Chase Cooper, Sebastian Riano, Angela M DiCiccio, Daniel L Worthington, Jeffrey P Clarkson, Michael Krames, Jianping Zhang, Ying Gao, Ling Zhou, Scott B Biering, Sarah A Stanley
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258336 (2021)
Decontaminating N95 respirators for reuse could mitigate shortages during the COVID-19 pandemic. Although the United States Center for Disease Control has identified Ultraviolet-C irradiation as one of the most promising methods for N95 decontaminati
Externí odkaz:
https://doaj.org/article/30b972ca089242bc8a9dde6d2e24f3e9
Autor:
Chunling Wang, Henry Puerta-Guardo, Scott B Biering, Dustin R Glasner, Edwina B Tran, Mark Patana, Trent A Gomberg, Carmel Malvar, Nicholas T N Lo, Diego A Espinosa, Eva Harris
Publikováno v:
PLoS Pathogens, Vol 15, Iss 7, p e1007938 (2019)
Arthropod-borne flaviviruses cause life-threatening diseases associated with endothelial hyperpermeability and vascular leak. We recently found that vascular leak can be triggered by dengue virus (DENV) non-structural protein 1 (NS1) via the disrupti
Externí odkaz:
https://doaj.org/article/bea72042ffd24c87845dfad58c2ce99e
Autor:
Qian Liu, Jacquelyn A Stone, Birgit Bradel-Tretheway, Jeffrey Dabundo, Javier A Benavides Montano, Jennifer Santos-Montanez, Scott B Biering, Anthony V Nicola, Ronald M Iorio, Xiaonan Lu, Hector C Aguilar
Publikováno v:
PLoS Pathogens, Vol 9, Iss 11, p e1003770 (2013)
Membrane fusion is essential for entry of the biomedically-important paramyxoviruses into their host cells (viral-cell fusion), and for syncytia formation (cell-cell fusion), often induced by paramyxoviral infections [e.g. those of the deadly Nipah v
Externí odkaz:
https://doaj.org/article/08b411ed74df42fd8d09735ad148346e
Publikováno v:
mBio, vol 14, iss 3
Replication complexes (RCs), formed by positive-strand (+) RNA viruses through rearrangements of host endomembranes, protect their replicating RNA from host innate immune defenses. We have shown that two evolutionarily conserved defense systems, auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75190fa74e086569d381438d9cb1637c
https://escholarship.org/uc/item/1dj121ks
https://escholarship.org/uc/item/1dj121ks
Autor:
Scott B. Biering, Francielle Tramontini Gomes de Sousa, Laurentia V. Tjang, Felix Pahmeier, Chi Zhu, Richard Ruan, Sophie F. Blanc, Trishna S. Patel, Caroline M. Worthington, Dustin R. Glasner, Bryan Castillo-Rojas, Venice Servellita, Nicholas T. N. Lo, Marcus P. Wong, Colin M. Warnes, Daniel R. Sandoval, Thomas Mandel Clausen, Yale A. Santos, Douglas M. Fox, Victoria Ortega, Anders M. Näär, Ralph S. Baric, Sarah A. Stanley, Hector C. Aguilar, Jeffrey D. Esko, Charles Y. Chiu, John E. Pak, P. Robert Beatty, Eva Harris
Publikováno v:
Nature communications, vol 13, iss 1
Severe COVID-19 is associated with epithelial and endothelial barrier dysfunction within the lung as well as in distal organs. While it is appreciated that an exaggerated inflammatory response is associated with barrier dysfunction, the triggers of v
Autor:
Nicholas T. N. Lo, Susan Z. Roodsari, Nicole L. Tin, Marcus P. Wong, Scott B. Biering, Eva Harris
Publikováno v:
J Virol
Members of the mosquito-borne flavivirus genus such as dengue (DENV), West Nile (WNV), and Zika (ZIKV) viruses cause distinct diseases and affect different tissues. We previously found that the secreted flaviviral nonstructural protein 1 (NS1) intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859933ca76aef2eabeb68f87df7ecba1
https://europepmc.org/articles/PMC9555157/
https://europepmc.org/articles/PMC9555157/
Autor:
Madison S. Strine, Wesley L. Cai, Jin Wei, Mia Madel Alfajaro, Renata B. Filler, Scott B. Biering, Sylvia Sarnik, Ajinkya Patil, Kasey S. Cervantes, Clayton K. Collings, Peter C. DeWeirdt, Ruth E. Hanna, Kevin Schofield, Christopher Hulme, Silvana Konermann, John G. Doench, Patrick D. Hsu, Cigall Kadoch, Qin Yan, Craig B. Wilen
Identifying host genes essential for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the potential to reveal novel drug targets and further our understanding of coronavirus disease 2019 (COVID-19). We previously performed a genome-wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4daff4ea1bbb6b966be856a427f6fc8
https://doi.org/10.1101/2022.09.13.507833
https://doi.org/10.1101/2022.09.13.507833