Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Scott A. Wolckenhauer"'
Autor:
Qi Liu, Chien-Hung Chou, Eda Canales, Roman Sakowicz, Steven Bondy, Tomas Cihlar, Albert Liclican, Diana M. Brainard, Anita Niedziela-Majka, William Rowe, Nikolai Novikov, Shekeba Ahmadyar, John R. Somoza, Randall L. Halcomb, Cheryl K. McDonald, Carina E. Cannizzaro, Nicolas Margot, Debi Jin, George Stepan, Qiaoyin Wu, Eric Hu, Judy Mwangi, Stephanie A. Leavitt, Todd C. Appleby, Robert L. Anderson, Scott E. Lazerwith, Schroeder Scott D, Tse Winston C, Gediminas Brizgys, Rebecca Begley, Yili Xu, Scott Sellers, Scott A. Wolckenhauer, Wesley I. Sundquist, Derek Hansen, Philip Morganelli, Andrew Mulato, Sheila Clancy, Xiaohong Liu, Anna Chiu, Eric S. Daar, Renee R. Ram, S. Swaminathan, Anne E. Chester, Melanie H. Wong, Ya-Pei Liu, John O. Link, Michael Graupe, Luong K. Tsai, Christian Callebaut, Latesh Lad, William E. Lee, Rujuta A. Bam, Terrence Z. Cai, Bing Lu, John K. Ling, Roland D. Saito, Magdeleine Hung, Armando G. Villaseñor, Peter Ruane, Nikos Pagratis, Martin S. Rhee, David Koditek, Gordon Crofoot, Giuseppe A. Papalia, Stephen R. Yant, Rob Hyland, Helen Yu, Jim Zheng, Jennifer R. Zhang, Gary I. Sinclair, Jiayao Li, Eric Singer
Publikováno v:
Nature
Oral antiretroviral agents provide life-saving treatments for millions of people living with HIV, and can prevent new infections via pre-exposure prophylaxis1–5. However, some people living with HIV who are heavily treatment-experienced have limite
Publikováno v:
Tetrahedron. 61:3371-3381
The stereochemical outcome of spiroannulations of N-protected 2-lithiopiperidines (generated by lithium di-tert-butyl biphenylide (LiDBB) mediated reductive lithiation of 2-cyanopiperidines) was investigated using deuterium labeled side-chains contai
Publikováno v:
Journal of the American Chemical Society. 132:9591-9593
Reductive lithiation of N-Boc alpha-amino nitriles generated alpha-amino alkyllithium reagents with unexpected selectivity. The intermediate radical prefers to align with the nitrogen lone pair, and this interaction leads to an A(1,3)-strain effect t
Autor:
J. Ashley Holleman, Ann M. Decker, Philip Abraham, Michael B. Gatch, Michael J. Forster, Andrew C. Mills, K. Timothy McElroy, Hernán A. Navarro, Scott A. Wolckenhauer, Antonio Landavazo, Bruce E. Blough, F. Ivy Carroll
A series of bupropion (1a) analogues (1b−1ff) were synthesized, and their in vitro and in vivo pharmacological properties evaluated with the goal of developing a 1a analogue that had better properties for treating addictions. Their in vitro pharmac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490f1fb12648bf323b7d84371360a3d5
https://europepmc.org/articles/PMC2841507/
https://europepmc.org/articles/PMC2841507/
Autor:
F. Ivy Carroll, Bruce E. Blough, Philip Abraham, Andrew C. Mills, J. Ashley Holleman, Scott A. Wolckenhauer, Ann M. Decker, Antonio Landavazo, K. Timothy McElroy, Hernán A. Navarro, Michael B. Gatch, Michael J. Forster
Publikováno v:
Journal of medicinal chemistry. 52(21)
A series of bupropion (1a) analogues (1b-1ff) were synthesized, and their in vitro and in vivo pharmacological properties evaluated with the goal of developing a 1a analogue that had better properties for treating addictions. Their in vitro pharmacol
Publikováno v:
ChemInform. 39
Publikováno v:
Organic letters. 9(21)
Rhodium-catalyzed reactions of sulfonate ester derivatives are biased strongly toward 1,6-insertion and thus offer a general method for assembling delta-sultones. Two protocols for staging this cyclization reaction are described, which capitalize on
Autor:
F. Ivy Carroll, Scott A. Wolckenhauer, Billy R. Martin, Wei Ma, M. I. Damaj, Philip Abraham, Hernán A. Navarro
A series of methyllycaconitine (1a, MLA) analogs was synthesized where the (S)-2-methylsuccinimidobenzoyl group in MLA was replaced with a (R)-2-methyl, 2,2-dimethyl-, 2,3-dimethyl, 2-phenyl-, and 2-cyclohexylsuccinimidobenzoyl (1b-f) group. The anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c3c7b0b34177e418ff42a3f5345439
https://europepmc.org/articles/PMC1850960/
https://europepmc.org/articles/PMC1850960/
Publikováno v:
Organic letters. 7(15)
[reaction: see text]. Three segment-coupling Prins approaches to the C3-C19 segment of phorboxazole B have been developed. One successful strategy utilized a novel TMSBr-mediated cyclization that proceeded with complete axial selectivity. Displacemen
Publikováno v:
ChemInform. 35
A general approach to tertiary alpha-aminoorganolithium reagents by reductive lithiation of alpha-aminonitriles has been developed. This class of organolithium nucleophiles reacts efficiently with carbonyl electrophiles or in intramolecular cyclizati