Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Scott A. Longwell"'
Autor:
Mason J. Appel, Scott A. Longwell, Maurizio Morri, Norma Neff, Daniel Herschlag, Polly M. Fordyce
Publikováno v:
ACS Omega, Vol 6, Iss 45, Pp 30542-30554 (2021)
Externí odkaz:
https://doaj.org/article/ab1df1c264c84e64b0e78e94148d3976
Autor:
Kara Brower, Robert R. Puccinelli, Craig J. Markin, Tyler C. Shimko, Scott A. Longwell, Bianca Cruz, Rafael Gomez-Sjoberg, Polly M. Fordyce
Publikováno v:
HardwareX, Vol 3, Iss , Pp 117-134 (2018)
Microfluidic technologies have been used across diverse disciplines (e.g. high-throughput biological measurement, fluid physics, laboratory fluid manipulation) but widespread adoption has been limited in part due to the lack of openly disseminated re
Externí odkaz:
https://doaj.org/article/c2ebeef00ba34878b2ec942257f44782
Autor:
Qitong Li, Jorik van de Groep, Adam K. White, Jung-Hwan Song, Scott A. Longwell, Polly M. Fordyce, Stephen R. Quake, Pieter G. Kik, Mark L. Brongersma
Publikováno v:
Nature Nanotechnology, 17(10). Nature Publishing Group
The ability to manipulate light and liquids on integrated optofluidics chips has spurred a myriad of important developments in biology, medicine, chemistry and display technologies. Here we show how the convergence of optofluidics and metasurface opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2dc3a906e9cfcb309c482afb1fc6a36
https://doi.org/10.1038/s41565-022-01197-y
https://doi.org/10.1038/s41565-022-01197-y
Autor:
Huy Quoc Nguyen, Jagoree Roy, Björn Harink, Nikhil P Damle, Naomi R Latorraca, Brian C Baxter, Kara Brower, Scott A Longwell, Tanja Kortemme, Kurt S Thorn, Martha S Cyert, Polly Morrell Fordyce
Publikováno v:
eLife, Vol 8 (2019)
Transient, regulated binding of globular protein domains to Short Linear Motifs (SLiMs) in disordered regions of other proteins drives cellular signaling. Mapping the energy landscapes of these interactions is essential for deciphering and perturbing
Externí odkaz:
https://doaj.org/article/7c2396e28d9c4a068245caf34c7ea70c
Autor:
Norma Neff, Daniel Herschlag, Maurizio Morri, Mason J. Appel, Polly M. Fordyce, Scott A. Longwell
Publikováno v:
ACS Omega, Vol 6, Iss 45, Pp 30542-30554 (2021)
ACS Omega
ACS Omega
New high-throughput biochemistry techniques complement selection-based approaches and provide quantitative kinetic and thermodynamic data for thousands of protein variants in parallel. With these advances, library generation rather than data collecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4571f8f960c22ccdcbd4d2fcaa0143a4
https://doaj.org/article/ab1df1c264c84e64b0e78e94148d3976
https://doaj.org/article/ab1df1c264c84e64b0e78e94148d3976
Autor:
Scott A. Longwell, Polly M. Fordyce
Publikováno v:
Lab Chip
Microfluidic devices are an enabling technology for many labs, facilitating a wide range of applications spanning high-throughput encapsulation, molecular separations, and long-term cell culture. In many cases, however, their utility is limited by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0804722aabad710a077aa4f664c436e1
https://doi.org/10.1039/c9lc00512a
https://doi.org/10.1039/c9lc00512a
Autor:
Qitong, Li, Jorik, van de Groep, Adam K, White, Jung-Hwan, Song, Scott A, Longwell, Polly M, Fordyce, Stephen R, Quake, Pieter G, Kik, Mark L, Brongersma
Publikováno v:
Nature nanotechnology. 17(10)
The ability to manipulate light and liquids on integrated optofluidics chips has spurred a myriad of important developments in biology, medicine, chemistry and display technologies. Here we show how the convergence of optofluidics and metasurface opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::994f93ce7b9cd8d8e6bfa541f8e77c73
https://pubmed.ncbi.nlm.nih.gov/36163506
https://pubmed.ncbi.nlm.nih.gov/36163506
Autor:
Polly M. Fordyce, Chiara Sabatti, Daniel A. Mokhtari, Scott A. Longwell, Daniel Herschlag, Mason J. Appel, Eyal Akiva, Fanny Sunden, Craig J. Markin
Go big or you'll get lost Rational mutagenesis is a common approach to investigating or engineering enzyme function in vitro, but the ease with which one can manipulate protein sequences belies many pitfalls in connecting sparse activity data to an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b174ff564afcbe0f4b6ac5f5b291826
https://doi.org/10.1101/2020.11.24.383182
https://doi.org/10.1101/2020.11.24.383182
Autor:
Polly M. Fordyce, Allison M. Keys, Yaron Orenstein, Daniel D. Le, Tyler C. Shimko, Scott A. Longwell, Arjun K. Aditham
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Transcription factors (TFs) are key proteins that bind DNA targets to coordinate gene expression in cells. Understanding how TFs recognize their DNA targets is essential for predicting how variations in regulatory sequence disrupt transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c1063ba25d2dd41ddbd966dc89b67a
http://europepmc.org/articles/PMC5910820
http://europepmc.org/articles/PMC5910820
Autor:
Kurt S. Thorn, Polly M. Fordyce, Naomi R. Latorraca, Scott A. Longwell, Björn Harink, Brian Baxter, Jagoree Roy, Tanja Kortemme, Nikhil P Damle, Martha S. Cyert, Kara Brower, Huy V. Nguyen
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Transient, regulated binding of globular protein domains to Short Linear Motifs (SLiMs) in disordered regions of other proteins drives cellular signaling. Mapping the energy landscapes of these interactions is essential for deciphering and perturbing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bac6753c903433fa381080685082f9
http://europepmc.org/articles/PMC6728138
http://europepmc.org/articles/PMC6728138