Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Scott A. Kanner"'
Autor:
Elena Poggio, Francesca Vallese, Andreas J. W. Hartel, Travis J. Morgenstern, Scott A. Kanner, Oliver Rauh, Flavia Giamogante, Lucia Barazzuol, Kenneth L. Shepard, Henry M. Colecraft, Oliver Biggs Clarke, Marisa Brini, Tito Calì
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-13 (2023)
Abstract Coronavirus disease (COVID-19) is a contagious respiratory disease caused by the SARS-CoV-2 virus. The clinical phenotypes are variable, ranging from spontaneous recovery to serious illness and death. On March 2020, a global COVID-19 pandemi
Externí odkaz:
https://doaj.org/article/6f24462f2be0478e821b38710e7c6258
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Long QT Syndrome (LQTS) is an acquired or inherited disorder characterized by prolonged QT interval, exertion-triggered arrhythmias, and sudden cardiac death. One of the most prevalent hereditary LQTS subtypes, LQT2, results from loss-of-function mut
Externí odkaz:
https://doaj.org/article/c3cfe93afea04cb696f6d8be7748f7b8
Publikováno v:
eLife, Vol 6 (2017)
The functional repertoire of surface ion channels is sustained by dynamic processes of trafficking, sorting, and degradation. Dysregulation of these processes underlies diverse ion channelopathies including cardiac arrhythmias and cystic fibrosis. Ub
Externí odkaz:
https://doaj.org/article/3e85b6d6162544b78189f2dd4209487d
Autor:
Xinle Zou, Sri Karthika Shanmugam, Scott A. Kanner, Kevin J. Sampson, Robert S. Kass, Henry M. Colecraft
The slow delayed rectifier potassium current, IKs, conducted through pore-forming Q1 and auxiliary E1 ion channel complexes is important for human cardiac action potential repolarization. During exercise or fright, IKs is up-regulated by protein kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fb9f1006466859bbe5d1f3e52f599c6
https://doi.org/10.1101/2022.09.12.507626
https://doi.org/10.1101/2022.09.12.507626
Publikováno v:
Nature Methods. 17:1245-1253
Impaired protein stability or trafficking underlies diverse ion channelopathies and represents an unexploited unifying principle for developing common treatments for otherwise dissimilar diseases. Ubiquitination limits ion channel surface density, bu
Autor:
Xinle Zou, Sri Karthika Shanmugam, Scott A. Kanner, Kevin J. Sampson, Robert S. Kass, Henry M. Colecraft
Publikováno v:
Biophysical Journal. 121:438a
Publikováno v:
Biophysical Journal. 118:326a
Autor:
Xinle Zou, Sri Karthika Shanmugam, Scott A Kanner, Kevin J Sampson, Robert S Kass, Henry M Colecraft
Publikováno v:
eLife, Vol 12 (2023)
The slow delayed rectifier potassium current, IKs, conducted through pore-forming Q1 and auxiliary E1 ion channel complexes is important for human cardiac action potential repolarization. During exercise or fright, IKs is up-regulated by protein kina
Externí odkaz:
https://doaj.org/article/2149105d957e415abf19bc5da42ba7a7