Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Scott A. Jeffers"'
Autor:
Scott A Jeffers
Publikováno v:
Cell and Gene Therapy Insights. 5:1275-1279
Autor:
Sonia T. Wennier, Emily A. Travanty, Megan W. Howard, Kathryn V. Holmes, Scott A. Jeffers, Max Smith, Larissa B. Thackray
Publikováno v:
Journal of Virology
The severe acute respiratory syndrome coronavirus (SARS-CoV) spike glycoprotein (S) is a class I viral fusion protein that binds to its receptor glycoprotein, human angiotensin converting enzyme 2 (hACE2), and mediates virus entry and cell-cell fusio
Publikováno v:
Journal of Structural Biology
The Spike (S) glycoprotein of coronaviruses (CoV) mediates viral entry into host cells. It contains two hydrophobic heptad repeat (HR) regions, denoted HRN and HRC, which oligomerize the S glycoprotein into a trimer in the native state and when activ
Autor:
Sonia M. Tusell, David E. Wentworth, Robert J. Mason, Scott A. Jeffers, Jenna E. Achenbach, Larissa B. Thackray, William D. Thomas, Erin M. Hemmila, James C. DeMartini, Mark D. Young, Babcock Gregory J, Donna M. Ambrosino, Kathryn V. Holmes, Laura Gillim-Ross
Publikováno v:
Proceedings of the National Academy of Sciences
Angiotensin-converting enzyme 2 (ACE2) is a receptor for SARS-CoV, the novel coronavirus that causes severe acute respiratory syndrome [Li, W. Moore, M. J., Vasilieva, N., Sui, J., Wong, S. K., Berne, M. A., Somasundaran, M., Sullivan, J. L., Luzuria
Publikováno v:
Journal of Virology. 76:12463-12472
The role of covalent modifications of the Ebola virus glycoprotein (GP) and the significance of the sequence identity between filovirus and avian retrovirus GPs were investigated through biochemical and functional analyses of mutant GPs. The expressi
Autor:
Félix A. Rey, Thomas Krey, Julia Chamot-Rooke, Christian Malosse, Célia Deville, Christine Girard-Blanc, Pablo Guardado-Calvo, Eric Guittet, François Bontems, Ieva Vasiliauskaite, Scott A. Jeffers, Stéphane Petres, Christina Sizun, Annalisa Meola, Carine van Heijenoort
Publikováno v:
Journal of Structural Biology
Journal of Structural Biology, Elsevier, 2014, 188 (1), pp.71-78. ⟨10.1016/j.jsb.2014.08.002⟩
Journal of Structural Biology, 2014, 188 (1), pp.71-78. ⟨10.1016/j.jsb.2014.08.002⟩
Journal of Structural Biology, Elsevier, 2014, 188 (1), pp.71-78. ⟨10.1016/j.jsb.2014.08.002⟩
Journal of Structural Biology, 2014, 188 (1), pp.71-78. ⟨10.1016/j.jsb.2014.08.002⟩
International audience; Nuclear magnetic resonance spectroscopy is a powerful tool to study structural and functional properties of proteins, provided that they can be enriched in stable isotopes such as (15)N, (13)C and (2)H. This is usually easy an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c35b59588d92465841fd7af2ae02cf
https://hal.archives-ouvertes.fr/hal-01077147
https://hal.archives-ouvertes.fr/hal-01077147
Autor:
Gérard Pehau-Arnaudet, Pablo Guardado-Calvo, Félix A. Rey, M. Alejandra Tortorici, Jean Luc Jestin, Scott A. Jeffers, Patrick England, Nicole D. Tischler, Eva Stettner, Jimena Pérez-Vargas, Eduardo A Bignon
Publikováno v:
PLoS Pathogens
PLoS Pathogens, 2016, 12 (10), pp.e1005813. ⟨10.1371/journal.ppat.1005813⟩
PLoS Pathogens, Public Library of Science, 2016, 12 (10), pp.e1005813. ⟨10.1371/journal.ppat.1005813⟩
'PLoS Pathogens ', vol: 12, pages: e1005813-1-e1005813-32 (2016)
PLoS Pathogens, Vol 12, Iss 10, p e1005813 (2016)
PLoS Pathogens, 2016, 12 (10), pp.e1005813. ⟨10.1371/journal.ppat.1005813⟩
PLoS Pathogens, Public Library of Science, 2016, 12 (10), pp.e1005813. ⟨10.1371/journal.ppat.1005813⟩
'PLoS Pathogens ', vol: 12, pages: e1005813-1-e1005813-32 (2016)
PLoS Pathogens, Vol 12, Iss 10, p e1005813 (2016)
Hantaviruses are zoonotic viruses transmitted to humans by persistently infected rodents, giving rise to serious outbreaks of hemorrhagic fever with renal syndrome (HFRS) or of hantavirus pulmonary syndrome (HPS), depending on the virus, which are as
Autor:
Tais A. P. F. Pimentel, Peter Burkhard, Robert S. Hodges, Zhe Yan, Scott A. Jeffers, Kathryn V. Holmes
Publikováno v:
Chemical Biology & Drug Design
Severe acute respiratory syndrome (SARS) is an infectious disease caused by a novel coronavirus that cost nearly 800 lives. While there have been no recent outbreaks of the disease, the threat remains as SARS coronavirus (SARS-CoV) like strains still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148fe2a4dc05aabe6ce94e01bc51b56f
https://europepmc.org/articles/PMC2756483/
https://europepmc.org/articles/PMC2756483/
Autor:
Tanya A. Miura, Rizwan Manzer, Karen E. Edeen, Shuanglin Wang, Kathryn V. Holmes, Gregory P. Cosgrove, Jieru Wang, L. D. Pearson, Robert J. Mason, Scott A. Jeffers, Eric C. Mossel, C. Joel Funk
Publikováno v:
Virology
Severe acute respiratory syndrome (SARS) is a disease characterized by diffuse alveolar damage. We isolated human alveolar type II cells and maintained them in a highly differentiated state. Type II cell cultures supported SARS-CoV replication as evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2497c401c11ef45f0e9ec1f56b904004
https://europepmc.org/articles/PMC2312501/
https://europepmc.org/articles/PMC2312501/
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780387262024
The primary receptor for SARS-CoV is ACE2, a metallopeptidase expressed on membranes of renal and cardiovascular tissues as well as the gastrointestinal tract. Marzi et al., showed that retroviral pseudotypes bearing the SARS-CoV glycoprotein could a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d5df151fa0dd3e67cccbd54ee94f541
https://doi.org/10.1007/978-0-387-33012-9_44
https://doi.org/10.1007/978-0-387-33012-9_44