Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Scott A. Hinger"'
Autor:
Jennifer M. Petrosino, Scott A. Hinger, Volha A. Golubeva, Juan M. Barajas, Lisa E. Dorn, Chitra C. Iyer, Hui-Lung Sun, W. David Arnold, Chuan He, Federica Accornero
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Muscle undergoes hypertrophy and atrophy in response to physiological stimuli or in pathological conditions, which is partially controlled through altered gene expression. Here the authors report that m6A methyltransferase METTL3 and mRNA m6A post-tr
Externí odkaz:
https://doaj.org/article/1a052b16c28446cb99698ffe0e5759b1
Autor:
Jacob Z. Longenecker, Jennifer M. Petrosino, Colton R. Martens, Scott A. Hinger, Charlotte J. Royer, Lisa E. Dorn, Daniel A. Branch, Joan Serrano, Kristin I. Stanford, George A. Kyriazis, Kedryn K. Baskin, Federica Accornero
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101343- (2021)
Regulation of organismal homeostasis in response to nutrient availability is a vital physiological process that involves inter-organ communication. Understanding the mechanisms controlling systemic cross-talk for the maintenance of metabolic health i
Externí odkaz:
https://doaj.org/article/2b209f5d12c04303857000b576c46e62
Autor:
Jessica J. Abner, Jeffrey L. Franklin, Margaret A. Clement, Scott A. Hinger, Ryan M. Allen, Xiao Liu, Stefanie Kellner, Junzhou Wu, John Karijolich, Qi Liu, Kasey C. Vickers, Peter Dedon, Alissa M. Weaver, Robert J. Coffey, James G. Patton
Publikováno v:
Heliyon, Vol 7, Iss 12, Pp e08519- (2021)
Extracellular vesicles (EVs) are capable of transferring cargo from donor to recipient cells, but precisely how cargo content is regulated for export is mostly unknown. For miRNA cargo, we previously showed that when compared to isogenic colorectal c
Externí odkaz:
https://doaj.org/article/0841125014be436eb18dc13a0b901a8c
Autor:
Scott A. Hinger, Diana J. Cha, Jeffrey L. Franklin, James N. Higginbotham, Yongchao Dou, Jie Ping, Lihua Shu, Nripesh Prasad, Shawn Levy, Bing Zhang, Qi Liu, Alissa M. Weaver, Robert J. Coffey, James G. Patton
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 715-725.e4 (2018)
Summary: The regulation and functional roles of secreted coding and long noncoding RNAs (lncRNAs; >200 nt) are largely unknown. We previously showed that mutant KRAS colorectal cancer (CRC) cells release extracellular vesicles (EVs) containing distin
Externí odkaz:
https://doaj.org/article/26715246100f4262bdc6f071c3bee262
Autor:
Jennifer M. Petrosino, Jacob Z. Longenecker, Colin D. Angell, Scott A. Hinger, Colton R. Martens, Federica Accornero
Publikováno v:
Matrix Biol
The regulation of skeletal muscle growth following pro-hypertrophic stimuli requires a coordinated response by different cell types that leads to extracellular matrix (ECM) remodeling and increases in muscle cross-sectional area. Indeed, matricellula
Autor:
Scott A. Hinger, James G. Patton, Robert J. Coffey, Jeffrey L. Franklin, Dennis K. Jeppesen, Jessica J. Abner
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Small extracellular vesicles (sEVs), 50–150 nm in diameter, have been proposed to mediate cell–cell communication with important implications in tumor microenvironment interactions, tumor growth, and metastasis. We previously showed that mutant K
Autor:
Jennifer M, Petrosino, Scott A, Hinger, Volha A, Golubeva, Juan M, Barajas, Lisa E, Dorn, Chitra C, Iyer, Hui-Lung, Sun, W David, Arnold, Chuan, He, Federica, Accornero
Publikováno v:
Nature Communications
Skeletal muscle serves fundamental roles in organismal health. Gene expression fluctuations are critical for muscle homeostasis and the response to environmental insults. Yet, little is known about post-transcriptional mechanisms regulating such fluc
Autor:
Scott A, Hinger, Jiangbo, Wei, Lisa E, Dorn, Bryan A, Whitson, Paul M L, Janssen, Chuan, He, Federica, Accornero
Publikováno v:
J Mol Cell Cardiol
Regulation of gene expression plays a fundamental role in cardiac stress-responses. Modification of coding transcripts by adenosine methylation (m(6)A) has recently emerged as a critical post-transcriptional mechanism underlying heart disease. Thousa
Autor:
James G. Patton, Scott A. Hinger, Robert J. Coffey, Shawn Levy, Bing Zhang, Jie Ping, Yongchao Dou, Nripesh Prasad, James N. Higginbotham, Qi Liu, Alissa M. Weaver, Diana J. Cha, Lihua Shu, Jeffrey L. Franklin
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 715-725.e4 (2018)
Summary: The regulation and functional roles of secreted coding and long noncoding RNAs (lncRNAs; >200 nt) are largely unknown. We previously showed that mutant KRAS colorectal cancer (CRC) cells release extracellular vesicles (EVs) containing distin
Autor:
Aimee D Wilde, Daniel J Snyder, Nicole E Putnam, Michael D Valentino, Neal D Hammer, Zachery R Lonergan, Scott A Hinger, Esar E Aysanoa, Catlyn Blanchard, Paul M Dunman, Gregory A Wasserman, John Chen, Bo Shopsin, Michael S Gilmore, Eric P Skaar, James E Cassat
Publikováno v:
PLoS Pathogens, Vol 11, Iss 12, p e1005341 (2015)
Staphylococcus aureus is capable of infecting nearly every organ in the human body. In order to infiltrate and thrive in such diverse host tissues, staphylococci must possess remarkable flexibility in both metabolic and virulence programs. To investi
Externí odkaz:
https://doaj.org/article/a6e5a9cd62c44ab8aae354d8e3ee9c9a