Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Scott A. Harper"'
Autor:
John A. Jernigan, David S. Stephens, David A. Ashford, Carlos Omenaca, Martin S. Topiel, Mark Galbraith, Michael Tapper, Tamara L. Fisk, Sherif Zaki, Tanja Popovic, Richard F. Meyer, Conrad P. Quinn, Scott A. Harper, Scott K. Fridkin, James J. Sejvar, Colin W. Shepard, Michelle McConnell, Jeannette Guarner, Wun-Ju Shieh, Jean M. Malecki, Julie L. Gerberding, James M. Hughes, Bradley A. Perkins
Publikováno v:
Emerging Infectious Diseases, Vol 7, Iss 6, Pp 933-944 (2001)
From October 4 to November 2, 2001, the first 10 confirmed cases of inhalational anthrax caused by intentional release of Bacillus anthracis were identified in the United States. Epidemiologic investigation indicated that the outbreak, in the Distric
Externí odkaz:
https://doaj.org/article/79ad69c0bde3438c95102e309b266a8d
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101295- (2024)
Adeno-associated viral vectors (AAVs) are a leading delivery system for gene therapy in animal models and humans. With several Food and Drug Administration-approved AAV gene therapies on the market, issues related to vector manufacturing have become
Externí odkaz:
https://doaj.org/article/f086c835d8624447a25c3ccb19294484
Publikováno v:
PhytoFrontiers, Vol 3, Iss 2, Pp 323-336 (2023)
‘Candidatus Phytoplasma pruni’ is the causative agent of X-disease on peach (Prunus persica) trees. Infected trees exhibit premature yellowing, leaf necrosis causing a shot-hole appearance, limb dieback, and eventual death. How pathogen infection
Externí odkaz:
https://doaj.org/article/bacf9553bb344e12b1e60b43ebcb72eb
Autor:
Sujatha Jagannathan, Jessica C. de Greef, Lawrence J. Hayward, Kyoko Yokomori, Davide Gabellini, Karlien Mul, Sabrina Sacconi, Jamshid Arjomand, June Kinoshita, Scott Q. Harper
Publikováno v:
Skeletal Muscle, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Facioscapulohumeral muscular dystrophy (FSHD) is the second most common genetic myopathy, characterized by slowly progressing and highly heterogeneous muscle wasting with a typical onset in the late teens/early adulthood [1]. Although the et
Externí odkaz:
https://doaj.org/article/e1293d0484d644569819137cb3f35b3b
Autor:
Nizar Y. Saad, Mustafa Al-Kharsan, Sara E. Garwick-Coppens, Gholamhossein Amini Chermahini, Madison A. Harper, Andrew Palo, Ryan L. Boudreau, Scott Q. Harper
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Facioscapulohumeral muscular dystrophy is a myopathy caused by aberrant de-repression of the DUX4 gene. Here, the authors show that miR-675 inhibits DUX4 expression and protects muscles from DUX4-mediated cell death when administered to mice using AA
Externí odkaz:
https://doaj.org/article/9598bc5d736548bfa909ada1aa74db34
Publikováno v:
HortScience, Vol 56, Iss 12, Pp 1471-1475 (2021)
Hop stunt viroid (HSVd) is one of the most important pathogens impacting hop production worldwide. It reduces yields, stunts growth, and is easily transmissible. HSVd can cause significant yield losses upward of 62% depending on the hop variety. This
Externí odkaz:
https://doaj.org/article/dbfdf526047e4152a997c3d7c906da73
Autor:
Marina Stavrou, Alexia Kagiava, Sarah G. Choudury, Matthew J. Jennings, Lindsay M. Wallace, Allison M. Fowler, Amanda Heslegrave, Jan Richter, Christina Tryfonos, Christina Christodoulou, Henrik Zetterberg, Rita Horvath, Scott Q. Harper, Kleopas A. Kleopa
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)
Charcot-Marie-Tooth disease type 1A (CMT1A), the most common inherited demyelinating peripheral neuropathy, is caused by PMP22 gene duplication. Overexpression of WT PMP22 in Schwann cells destabilizes the myelin sheath, leading to demyelination and
Externí odkaz:
https://doaj.org/article/58c621808db747a4a8de06b28aacae40
Autor:
Afrooz Rashnonejad, Gholamhossein Amini-Chermahini, Noah K. Taylor, Nicolas Wein, Scott Q. Harper
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 476-486 (2021)
Facioscapulohumeral muscular dystrophy (FSHD) arises from epigenetic changes that de-repress the DUX4 gene in muscle. The full-length DUX4 protein causes cell death and muscle toxicity, and therefore we hypothesize that FSHD therapies should center o
Externí odkaz:
https://doaj.org/article/69e3df8c0b8b4176b6d912000436a430
Autor:
Michael Kyba, Robert J. Bloch, Julie Dumonceaux, Scott Q. Harper, Silvère M. van der Maarel, Francis M. Sverdrup, Kathryn R. Wagner, Baziel van Engelen, Yi-Wen Chen
Publikováno v:
Skeletal Muscle, Vol 10, Iss 1, Pp 1-6 (2020)
Externí odkaz:
https://doaj.org/article/99d83c376e0b4c99b077e8a67c8cce9c
Autor:
Jenna M. Kastenschmidt, Gerald Coulis, Philip K. Farahat, Phillip Pham, Rodolfo Rios, Therese T. Cristal, Ali H. Mannaa, Rachel E. Ayer, Rayan Yahia, Archis A. Deshpande, Brandon S. Hughes, Adam K. Savage, Carlee R. Giesige, Scott Q. Harper, Richard M. Locksley, Tahseen Mozaffar, S. Armando Villalta
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108997- (2021)
Summary: Despite the well-accepted view that chronic inflammation contributes to the pathogenesis of Duchenne muscular dystrophy (DMD), the function and regulation of eosinophils remain an unclear facet of type II innate immunity in dystrophic muscle
Externí odkaz:
https://doaj.org/article/415bf515be5348feade1d4581741b4f9