Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Scott A Souza"'
Autor:
Julia A. Alvarez, Elisabet Gas-Pascual, Sahil Malhi, Juan C. Sánchez-Arcila, Ferdinand Ngale Njume, Hanke van der Wel, Yanlin Zhao, Laura García-López, Gabriella Ceron, Jasmine Posada, Scott P. Souza, George S. Yap, Christopher M. West, Kirk D. C. Jensen
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Glycosylphosphatidylinositols (GPIs) are highly conserved anchors for eukaryotic cell surface proteins. The apicomplexan parasite, Toxoplasma gondii, is a widespread intracellular parasite of warm-blooded animals whose plasma membrane is cov
Externí odkaz:
https://doaj.org/article/e16045143206407581d3f75afa37d03f
Autor:
Nath Zungsontiporn, Raquel R Tello, Guangxiang Zhang, Brooks I Mitchell, Matthew Budoff, Kalpana J Kallianpur, Beau K Nakamoto, Sheila M Keating, Philip J Norris, Lishomwa C Ndhlovu, Scott A Souza, Cecilia M Shikuma, Dominic C Chow
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149143 (2016)
BACKGROUND:Persistent inflammation and immune activation has been hypothesized to contribute to increased prevalence of subclinical atherosclerosis and cardiovascular disease (CVD) risk in patients with chronic HIV infection. In this study, we examin
Externí odkaz:
https://doaj.org/article/c3589e2f6c3f4ace861f4ecf0437a849
Publikováno v:
Biologics: Targets & Therapy, Vol 2008, Iss Issue 4, Pp 917-921 (2008)
Dominic C Chow, Anne Tasaki, Jill Ono, Bruce Shiramizu, Scott A SouzaHawaii AIDS Clinical Research Program, University of Hawaii, Honolulu, HI, USABackground: HIV-associated lipodystrophy syndrome is strongly associated with antiretroviral treatment
Externí odkaz:
https://doaj.org/article/d41ebaad78044dadaeb72034f18709b8
Autor:
Angel K. Kongsomboonvech, Laura García-López, Ferdinand Njume, Felipe Rodriguez, Scott P. Souza, Alex Rosenberg, Kirk D. C. Jensen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionToxoplasma gondii induces a strong CD8 T cell response characterized by the secretion of IFNγ that promotes host survival during infection. The initiation of CD8 T cell IFNγ responses in vitro differs widely between clonal lineage strai
Externí odkaz:
https://doaj.org/article/2eef35b30b284a818d2de5862f5266f3
Autor:
Scott P Souza, Samantha D Splitt, Juan C Sànchez-Arcila, Julia A Alvarez, Jessica N Wilson, Safuwra Wizzard, Zheng Luo, Nicole Baumgarth, Kirk D C Jensen
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010081 (2021)
Protective immunity to parasitic infections has been difficult to elicit by vaccines. Among parasites that evade vaccine-induced immunity is Toxoplasma gondii, which causes lethal secondary infections in chronically infected mice. Here we report that
Externí odkaz:
https://doaj.org/article/51630f80687a4dba9e15b4b67857c227
Autor:
Brooks I. Mitchell, Cecilia M. Shikuma, Rasmus M. Birn, Scott A. Souza, Lishomwa C. Ndhlovu, Lindsay B Kohorn, Dominic C. Chow, Robert H. Paul, Kalpana J. Kallianpur
Publikováno v:
Journal of Behavioral and Brain Science. 10:344-370
Background: Brain atrophy and cognitive deficits persist among individuals with suppressed HIV disease. The impact of cannabis use is unknown. Methods: HIV+ and HIV- participants underwent cross-sectional magnetic resonance imaging and neuropsycholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb8d330e45c5eae3142dd785edba7c3f
https://doi.org/10.4236/jbbs.2020.108022
https://doi.org/10.4236/jbbs.2020.108022
Autor:
Cecilia M. Shikuma, Ivo Novita SahBandar, Howard N. Hodis, Lishomwa C. Ndhlovu, Iain MacPherson, Scott Bowler, Chathura Siriwardhana, Yanjie Li, Makoa Mau, Dominic C. Chow, Jakrin Kewcharoen, Scott A. Souza, Brooks I. Mitchell, Louie Mar A Gangcuangco
Publikováno v:
AIDS Res Hum Retroviruses
Maximum carotid plaque thickness (MCPT) measures the largest plaque thickness in the carotid artery and reflects atherosclerosis plaque burden. MCPT may be a better predictor of cardiovascular disease than carotid artery intima-media thickness (cIMT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2971e6b383d8ecd10bb13ff87f9e4e8
https://pubmed.ncbi.nlm.nih.gov/32862657
https://pubmed.ncbi.nlm.nih.gov/32862657
Autor:
Scott P. Souza, Samantha D. Splitt, Julia A. Alvarez, Juan C. Sanchez-Arcila, Jessica N. Wilson, Safuwra Wizzard, Zheng Luo, Nicole Baumgarth, Kirk D.C. Jensen
Protective immunity to parasitic infections has been difficult to elicit by vaccines. Among parasites that evade vaccine-induced immunity is Toxoplasma gondii, which causes lethal secondary infections in chronically infected mice. Here we report that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9bd9872e3e0bb964180093a59e226ab
https://doi.org/10.1101/2020.06.26.174151
https://doi.org/10.1101/2020.06.26.174151
Autor:
Cecilia M. Shikuma, Lishomwa C. Ndhlovu, Nancy Hanks, Ivo N. SahBandar, Lindsay B Kohorn, Glen M. Chew, Louie Mar A Gangcuangco, Eun-young Park, Dominic C. Chow, Mariana Gerschenson, Scott A. Souza
Publikováno v:
AIDS Res Hum Retroviruses
Increased negative immune checkpoint receptors (NCR) on T cells are linked to T cell exhaustion, dysfunctional effector responses, and HIV viral persistence. Metformin, an oral hypoglycemic agent used for diabetes, may have previously unrecognized be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50de7d5e8f05167a17353b6cc5eabaed
https://europepmc.org/articles/PMC7185314/
https://europepmc.org/articles/PMC7185314/
Autor:
Dominic C. Chow, B. L. Mitchell, Scott A. Souza, Scott Bowler, D. Ogata-Arakaki, Cecilia M. Shikuma, R. Yee, Chathura Siriwardhana, Michelle L D'Antoni, Louie Mar A Gangcuangco, Lishomwa C. Ndhlovu
Publikováno v:
HIV researchclinical practice. 20(4-5)
Background: Chronic HIV is associated with increased inflammation and tissue fibrosis despite suppressive antiretroviral therapy (ART). Monocytes and macrophages have been implicated in the pathoge...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e280f600927d107d5bd78db94b5d38a
https://pubmed.ncbi.nlm.nih.gov/32013805
https://pubmed.ncbi.nlm.nih.gov/32013805