Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Scott A Small"'
Autor:
Xinyang Feng, Jia Guo, Hannah C Sigmon, Richard P Sloan, Adam M Brickman, Frank A Provenzano, Scott A Small, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0234255 (2020)
'Normal aging' in the brain refers to age-related changes that occur independent of disease, in particular Alzheimer's disease. A major barrier to mapping normal brain aging has been the difficulty in excluding the earliest preclinical stages of Alzh
Externí odkaz:
https://doaj.org/article/0957878b619644e89357c6b79e3d6770
Autor:
Li Liu, Valerie Drouet, Jessica W Wu, Menno P Witter, Scott A Small, Catherine Clelland, Karen Duff
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31302 (2012)
Tauopathy in the brain of patients with Alzheimer's disease starts in the entorhinal cortex (EC) and spreads anatomically in a defined pattern. To test whether pathology initiating in the EC spreads through the brain along synaptically connected circ
Externí odkaz:
https://doaj.org/article/c3290960259e4ec9a3089042ea462901
Autor:
Junhao Zhang, Vishwanatha M. Rao, Ye Tian, Yanting Yang, Nicolas Acosta, Zihan Wan, Pin-Yu Lee, Chloe Zhang, Lawrence S. Kegeles, Scott A. Small, Jia Guo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Schizophrenia is a chronic neuropsychiatric disorder that causes distinct structural alterations within the brain. We hypothesize that deep learning applied to a structural neuroimaging dataset could detect disease-related alteration and imp
Externí odkaz:
https://doaj.org/article/a4b05c2f97d943c087626eb390ea8efd
Autor:
Chen Liu, Nanyan Zhu, Haoran Sun, Junhao Zhang, Xinyang Feng, Sabrina Gjerswold-Selleck, Dipika Sikka, Xuemin Zhu, Xueqing Liu, Tal Nuriel, Hong-Jian Wei, Cheng-Chia Wu, J. Thomas Vaughan, Andrew F. Laine, Frank A. Provenzano, Scott A. Small, Jia Guo
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
While MRI contrast agents such as those based on Gadolinium are needed for high-resolution mapping of brain metabolism, these contrast agents require intravenous administration, and there are rising concerns over their safety and invasiveness. Furthe
Externí odkaz:
https://doaj.org/article/9e36da58adf7405cbffbe5a76a2c545a
Autor:
Rakshathi Basavaraju, Jeanelle France, Hannah C. Sigmon, Ragy R. Girgis, Gary Brucato, Jeffrey A. Lieberman, Scott A. Small, Frank A. Provenzano
Publikováno v:
Schizophrenia Research. 255:246-255
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf554b6358e2f3f65a85afacb96a0e6f
https://doi.org/10.1016/j.schres.2023.03.027
https://doi.org/10.1016/j.schres.2023.03.027
Autor:
Allison Knupp, Swati Mishra, Refugio Martinez, Jacquelyn E. Braggin, Marcell Szabo, Chizuru Kinoshita, Dale W. Hailey, Scott A. Small, Suman Jayadev, Jessica E. Young
Publikováno v:
Cell Reports, Vol 31, Iss 9, Pp - (2020)
Summary: SORL1/SORLA is a sorting receptor involved in retromer-related endosomal traffic and an Alzheimer’s disease (AD) risk gene. Using CRISPR-Cas9, we deplete SORL1 in hiPSCs to ask if loss of SORL1 contributes to AD pathogenesis by endosome dy
Externí odkaz:
https://doaj.org/article/19746c1d19d847c3a60732df360c1e8c
Autor:
Martin Lukindu, Christina M. Bergey, Rachel M. Wiltshire, Scott T. Small, Brian P. Bourke, Jonathan K. Kayondo, Nora J. Besansky
Publikováno v:
Parasites & Vectors, Vol 11, Iss 1, Pp 1-12 (2018)
Abstract Background Understanding population genetic structure in the malaria vector Anopheles gambiae (s.s.) is crucial to inform genetic control and manage insecticide resistance. Unfortunately, species characteristics such as high nucleotide diver
Externí odkaz:
https://doaj.org/article/cbe6a048bed7424ead9d12cd3c368294
Autor:
Xinyang Feng, Marla J. Hamberger, Hannah C. Sigmon, Jia Guo, Scott A. Small, Frank A. Provenzano
Publikováno v:
NeuroImage: Clinical, Vol 19, Iss , Pp 911-917 (2018)
Steady-state cerebral blood volume (CBV) is tightly coupled to regional cerebral metabolism, and CBV imaging is a variant of MRI that has proven useful in mapping brain dysfunction. CBV derived from exogenous contrast-enhanced MRI can generate sub-mi
Externí odkaz:
https://doaj.org/article/c77953026bee4ef1a69b474857c5fef7
Autor:
Karen Barker, Marialena Trivella, Andrew James Price, Scott R Small, Garrett S Bullock, Sara Khalid
Publikováno v:
BMJ Open, Vol 9, Iss 12 (2019)
Objectives Wearable motion sensors are used with increasing frequency in the evaluation of gait, function and physical activity within orthopaedics and sports medicine. The integration of wearable technology into the clinical pathway offers the abili
Externí odkaz:
https://doaj.org/article/07997dea4a8a4c2dae4e4aab3575d0c6