Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Scott A Chisholm"'
Autor:
Sreejoyee Ghosh, Scott A Chisholm, Madeline Dans, Asha Lakkavaram, Kit Kennedy, Stuart A Ralph, Natalie A Counihan, Tania F de Koning-Ward
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193538 (2018)
The ability of Plasmodium parasites to egress from their host red blood cell is critical for the amplification of these parasites in the blood. Previous forward chemical genetic approaches have implicated the subtilisin-like protease (SUB1) and the c
Externí odkaz:
https://doaj.org/article/fe4e9dc4fac34c4ea30a511940745b33
Autor:
Natalie A Counihan, Scott A Chisholm, Hayley E Bullen, Anubhav Srivastava, Paul R Sanders, Thorey K Jonsdottir, Greta E Weiss, Sreejoyee Ghosh, Brendan S Crabb, Darren J Creek, Paul R Gilson, Tania F de Koning-Ward
Publikováno v:
eLife, Vol 6 (2017)
Plasmodium falciparum parasites, the causative agents of malaria, modify their host erythrocyte to render them permeable to supplementary nutrient uptake from the plasma and for removal of toxic waste. Here we investigate the contribution of the rhop
Externí odkaz:
https://doaj.org/article/97ed3bf0078b4d8eba8c42a7a6284862
Autor:
Scott A Chisholm, Emma McHugh, Rachel Lundie, Matthew W A Dixon, Sreejoyee Ghosh, Meredith O'Keefe, Leann Tilley, Ming Kalanon, Tania F de Koning-Ward
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149296 (2016)
Pathogenesis of malaria infections is linked to remodeling of erythrocytes, a process dependent on the trafficking of hundreds of parasite-derived proteins into the host erythrocyte. Recent studies have demonstrated that the Plasmodium translocon of
Externí odkaz:
https://doaj.org/article/e6bb378e44ec4e6ebf2584b792d91a16
Autor:
Steven Batinovic, Emma McHugh, Scott A. Chisholm, Kathryn Matthews, Boiyin Liu, Laure Dumont, Sarah C. Charnaud, Molly Parkyn Schneider, Paul R. Gilson, Tania F. de Koning-Ward, Matthew W. A. Dixon, Leann Tilley
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Plasmodium-infected red blood cells export virulence factors, such asPfEMP1, to the cell surface. Here, the authors identify a protein complex termed EPIC that interacts with PfEMP1 during export, and they show that knockdown of an EPIC component aff
Externí odkaz:
https://doaj.org/article/9946bce78ad340cbacc3880e1452c735
Publikováno v:
Expert Opinion on Drug Discovery. 15:415-425
Introduction: Bromodomains (BRDs) bind to acetylated lysine residues, often on histones. The BRD proteins can contribute to gene regulation either directly through enzymatic activity or indirectly through recruitment of chromatin-modifying complexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaa1564abce40da9b0404f271a16f6c1
https://doi.org/10.1080/17460441.2020.1704251
https://doi.org/10.1080/17460441.2020.1704251
Autor:
Chantelle R. Reid, Olivia A. Galea, Scott M. Chisholm, Michaela E. Mersch, Jocelyn Nullmeyer, Hayden D. Bristow, Julia Treleaven
Publikováno v:
Musculoskeletal Science and Practice. 42:166-172
The three-metre tandem gait test (TG) is used to assess postural control during locomotion following sports concussion. However, values used to determine a pass/fail result are currently based on young athletic populations. Times for test completion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74719f22250c429ec8fb19ab0e9feec
https://doi.org/10.1016/j.msksp.2019.04.006
https://doi.org/10.1016/j.msksp.2019.04.006
Autor:
Lee M. Yeoh, Jingyi Tang, Anthony T. Papenfuss, Scott A. Chisholm, Paul R. Gilson, Michael F. Duffy, Michaela Petter, Karen P. Day
Publikováno v:
Epigenetics & Chromatin
Background The malaria parasite Plasmodium falciparum has an unusually euchromatic genome with poorly conserved positioning of nucleosomes in intergenic sequences and poorly understood mechanisms of gene regulation. Variant histones and histone modif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bc8a0ca38db2a831cb870e7269a1c2
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/17738
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/17738
Publikováno v:
Expert opinion on drug discovery. 15(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8632e3c5dcc58071e6dff944a50055e
https://pubmed.ncbi.nlm.nih.gov/31870185
https://pubmed.ncbi.nlm.nih.gov/31870185
Publikováno v:
International Journal for Parasitology. 47:119-127
When in their human hosts, malaria parasites spend most of their time housed within vacuoles inside erythrocytes and hepatocytes. The parasites extensively modify their host cells to obtain nutrients, prevent host cell breakdown and avoid the immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2459aa863f660112e24e1da3c9ed1625
https://doi.org/10.1016/j.ijpara.2016.06.001
https://doi.org/10.1016/j.ijpara.2016.06.001
Autor:
Scott A. Chisholm, Benjamin K. Dickerman, Paul R Sanders, Ming Kalanon, Thomas Nebl, Paul R. Gilson, Tania F. de Koning-Ward, Kathryn Matthews
Publikováno v:
The FEBS journal. 285(11)
The pathogenic nature of malaria infections is due in part to the export of hundreds of effector proteins that actively remodel the host erythrocyte. The Plasmodium translocon of exported proteins (PTEX) has been shown to facilitate the trafficking o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f25052da9cdb7c52700e08082d380fb7
https://pubmed.ncbi.nlm.nih.gov/29637707
https://pubmed.ncbi.nlm.nih.gov/29637707