Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Scott A, Yuzwa"'
Autor:
Stephanie Ouzikov, Kyshona M. Edwards, Tanvi Anandampillai, Samuel Watanabe, Daniela Lozano Casasbuenas, Karen K. Siu, Danyon Harkins, Aaron Dou, Danielle Jeong, Jeffrey E. Lee, Scott A. Yuzwa
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Adult Neural Stem Cells (aNSCs) in the ventricular-subventricular zone (V-SVZ) are largely quiescent. Here, we characterize the mechanism underlying the functional role of a cell-signalling inhibitory protein, LRIG1, in the control of aNSCs
Externí odkaz:
https://doaj.org/article/7061831eb85c4e67af4dfffcef284c78
Autor:
Erica Y. Scott, Nickie Safarian, Daniela Lozano Casasbuenas, Michael Dryden, Teodora Tockovska, Shawar Ali, Jiaxi Peng, Emerson Daniele, Isabel Nie Xin Lim, K. W. Annie Bang, Shreejoy Tripathy, Scott A. Yuzwa, Aaron R. Wheeler, Maryam Faiz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Astrocytes, a type of glial cell in the central nervous system (CNS), adopt diverse states in response to injury that are influenced by their location relative to the insult. Here, we describe a platform for spatially resolved, single-cell t
Externí odkaz:
https://doaj.org/article/92b2bf20c25e4738800225acc0ed64c1
Autor:
Nicole L. Dittmann, Pouria Torabi, Adrianne E. S. Watson, Scott A. Yuzwa, Anastassia Voronova
Publikováno v:
Stem Cell Reviews and Reports. 19:983-1000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::425139fe2d712bd7adf7af9809cc48c5
https://doi.org/10.1007/s12015-022-10492-z
https://doi.org/10.1007/s12015-022-10492-z
Autor:
Scott A. Yuzwa, Michael J. Borrett, Brendan T. Innes, Anastassia Voronova, Troy Ketela, David R. Kaplan, Gary D. Bader, Freda D. Miller
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3970-3986 (2017)
Adult neural stem cells (NSCs) derive from embryonic precursors, but little is known about how or when this occurs. We have addressed this issue using single-cell RNA sequencing at multiple developmental time points to analyze the embryonic murine co
Externí odkaz:
https://doaj.org/article/42cb4d38b3de47c5ab51b0e8c197f9ce
Autor:
Sibel Naska, Scott A. Yuzwa, Adam P.W. Johnston, Smitha Paul, Kristen M. Smith, Maryline Paris, Michael V. Sefton, Alessandro Datti, Freda D. Miller, David R. Kaplan
Publikováno v:
Stem Cell Reports, Vol 6, Iss 1, Pp 74-84 (2016)
Here, we asked whether we could identify pharmacological agents that enhance endogenous stem cell function to promote skin repair, focusing on skin-derived precursors (SKPs), a dermal precursor cell population. Libraries of compounds already used in
Externí odkaz:
https://doaj.org/article/4cd59b2569bd494892c8e39f93f2704b
Autor:
Nicole L, Dittmann, Pouria, Torabi, Adrianne E S, Watson, Scott A, Yuzwa, Anastassia, Voronova
Publikováno v:
Stem cell reviews and reports.
The mammalian adult brain contains two neural stem and precursor (NPC) niches: the subventricular zone [SVZ] lining the lateral ventricles and the subgranular zone [SGZ] in the hippocampus. From these, SVZ NPCs represent the largest NPC pool. While S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5af37839c3ba676ac3ddc2ed6b340ed
https://pubmed.ncbi.nlm.nih.gov/36617597
https://pubmed.ncbi.nlm.nih.gov/36617597
Autor:
Ethiraj Ravindran, Hao Hu, Scott A Yuzwa, Luis R Hernandez-Miranda, Nadine Kraemer, Olaf Ninnemann, Luciana Musante, Eugen Boltshauser, Detlev Schindler, Angela Hübner, Hans-Christian Reinecker, Hans-Hilger Ropers, Carmen Birchmeier, Freda D Miller, Thomas F Wienker, Christoph Hübner, Angela M Kaindl
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006746 (2017)
Mid-hindbrain malformations can occur during embryogenesis through a disturbance of transient and localized gene expression patterns within these distinct brain structures. Rho guanine nucleotide exchange factor (ARHGEF) family members are key for co
Externí odkaz:
https://doaj.org/article/5b284e26306f4ccab2416e2e9381e227
Publikováno v:
Biochemical and biophysical research communications. 585
Cancer stem cells have an important role in tumour biology. While their identity in haematological malignancies is clearly defined, stem cell identity remains elusive in some solid tumours. Clear cell renal cell carcinoma (ccRCC) represents the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64dac7566d57f715955a38c8c4d3508
https://pubmed.ncbi.nlm.nih.gov/34813980
https://pubmed.ncbi.nlm.nih.gov/34813980
Autor:
Danielle Jeong, David L. Kaplan, Freda D. Miller, Archana Gengatharan, Kyshona Edwards, Scott A. Yuzwa, Armen Saghatelyan, Daniela Lozano Casasbuenas
Publikováno v:
Cell reports. 33(2)
Here, we ask how neural stem cells (NSCs) transition in the developing neocortex from a rapidly to a slowly proliferating state, a process required to maintain lifelong stem cell pools. We identify LRIG1, known to regulate receptor tyrosine kinase si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d2c242ba76749789ec4c05ced128d5
https://pubmed.ncbi.nlm.nih.gov/33053360
https://pubmed.ncbi.nlm.nih.gov/33053360
Autor:
David R. Kaplan, Scott A. Yuzwa, Smitha Paul, Freda D. Miller, Matthew J. Carr, Matthew P. Krause, Mekayla Storer, Adam P. W. Johnston, Neemat Mahmud, Karen Louise Jones
Publikováno v:
Cell Stem Cell. 19:433-448
Adult mammals have lost multi-tissue regenerative capacity, except for the distal digit, which is able to regenerate via mechanisms that remain largely unknown. Here, we show that, after adult mouse distal digit removal, nerve-associated Schwann cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bafc41fc5f6c697510c17c80dd8fa9de
https://doi.org/10.1016/j.stem.2016.06.002
https://doi.org/10.1016/j.stem.2016.06.002