Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Scott A, Becker"'
Autor:
Scott A. Becker, Brian G. Petrich, Bing Yu, Kristopher A. Knight, Harrison C. Brown, Sunil S. Raikar, Christopher B. Doering, H. Trent Spencer
Publikováno v:
Molecular Therapy: Oncolytics, Vol 29, Iss , Pp 145-157 (2023)
Adoptive cell therapy (ACT) utilizing γδ T cells is becoming a promising option for the treatment of cancer, because it offers an off-the-shelf allogeneic product that is safe, potent, and clinically effective. Approaches to engineer or enhance imm
Externí odkaz:
https://doaj.org/article/53f3291d08774bab9a7136bad26a24d2
Autor:
Lauren C. Fleischer, Scott A. Becker, Rebecca E. Ryan, Andrew Fedanov, Christopher B. Doering, H. Trent Spencer
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss , Pp 149-160 (2020)
Chimeric antigen receptor (CAR)-modified T cells have demonstrated efficacy against B cell leukemias/lymphomas. However, redirecting CAR T cells to malignant T cells is more challenging due to product-specific cis- and trans-activation causing fratri
Externí odkaz:
https://doaj.org/article/57c3a61041d34dbe85e0bb0f4d7cdf17
Critical evaluation of an autologous peripheral blood mononuclear cell-based humanized cancer model.
Autor:
Harinarayanan Janakiraman, Scott A Becker, Alexandra Bradshaw, Mark P Rubinstein, Ernest Ramsay Camp
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273076 (2022)
The use of humanized mouse models for oncology is rapidly expanding. Autologous patient-derived systems are particularly attractive as they can model the human cancer's heterogeneity and immune microenvironment. In this study, we developed an autolog
Externí odkaz:
https://doaj.org/article/6c702c4a6e5e4432842b2a58e8485956
Autor:
Sikha Singh, Michele Caggana, Carol Johnson, Rachel Lee, Guisou Zarbalian, Amy Gaviglio, Alisha Keehn, Mia Morrison, Scott J. Becker, Jelili Ojodu
Publikováno v:
International Journal of Neonatal Screening, Vol 8, Iss 2, p 28 (2022)
Newborn screening (NBS) is an essential public health service that performs screening to identify those newborns at increased risk for a panel of disorders, most of which are genetic. The goal of screening is to link those newborns at the highest ris
Externí odkaz:
https://doaj.org/article/da6acc79c2764310ae793f29bfd2934f
Autor:
Milagros C. Romay, Nam Che, Scott N. Becker, Delila Pouldar, Raffi Hagopian, Xinshu Xiao, Aldons J. Lusis, Judith A. Berliner, Mete Civelek
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 1, Pp 38-50 (2015)
Exposure of endothelial cells (ECs) to agents such as oxidized glycerophospholipids (oxGPs) and cytokines, known to accumulate in atherosclerotic lesions, perturbs the expression of hundreds of genes in ECs involved in inflammatory and other biologic
Externí odkaz:
https://doaj.org/article/1f59c493c62f44e49387fa92098d55ba
Autor:
Immaculate Sware Semesi, Diederik A Bleijs, Michelle Nalabandian, Ernesto Gozzer, Elizabeth E. Cameron, Wilmot G. James, Mark W J van Passel, Zibusiso M Masuku, Chikwe Ihekweazu, Anthony Ahumibe, Aamer Ikram, Emmanuel Agogo, Irma Makalinao, S Nikkari, Sacha Wallace-Sankarsingh, Hayley Anne Severance, Katherine Budeski, Scott J Becker, Maureen Ellis, Faheem Tahir, Sabrina Brizee
Publikováno v:
Health Security. 17:495-503
Biosecurity and biosafety measures are designed to mitigate intentional and accidental biological risks that pose potentially catastrophic consequences to a country's health system, security, and political and economic stability. Unfortunately, biose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c79768403f319a4b7d1f713c97e8013
https://doi.org/10.1089/hs.2019.0121
https://doi.org/10.1089/hs.2019.0121
Publikováno v:
Science (New York, N.Y.). 373(6559)
Coronavirus 3′-to-5′ exoribonuclease (ExoN), residing in the nonstructural protein (nsp) 10–nsp14 complex, boosts replication fidelity by proofreading RNA synthesis and is critical for the virus life cycle. ExoN also recognizes and excises nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c195e3fec4b8b9aa1cd34a67e42195f0
https://pubmed.ncbi.nlm.nih.gov/34315827
https://pubmed.ncbi.nlm.nih.gov/34315827
Publikováno v:
The New England journal of medicine. 385(5)
Identifying and Tracking SARS-CoV-2 Variants Funding designated for increasing understanding of SARS-CoV-2 variants could be used in ways that would help guide the current pandemic response and yie...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57021ac9d81852c9abf6b47ccc4060e7
https://pubmed.ncbi.nlm.nih.gov/34107199
https://pubmed.ncbi.nlm.nih.gov/34107199
Publikováno v:
Journal of Public Health Management and Practice
Public health laboratories have played a central role in the US response to COVID-19. Since the earliest days, myriad issues have impeded the laboratory community's ability to keep pace with the overwhelming demand for effective tests. In this articl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e66e7911a65357ebf82957b7ea1c83d
https://pubmed.ncbi.nlm.nih.gov/33239571
https://pubmed.ncbi.nlm.nih.gov/33239571
Autor:
Scott A, Becker, Roberto, Spreafico, Jennie L, Kit, Rob, Brown, Maria, Likhogrud, Wei, Fang, Matthew C, Posewitz, Joseph C, Weissman, Randor, Radakovits
Publikováno v:
Microbiology Resource Announcements
Picochlorum celeri is a fast-growing marine microalga with high biomass productivity. Here, we report the use of PacBio sequencing to assemble the phased diploid genome of P. celeri.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::460eff22d69cd32be5d95440d7444858
https://pubmed.ncbi.nlm.nih.gov/32409528
https://pubmed.ncbi.nlm.nih.gov/32409528