Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Scott, Wasdo"'
Autor:
Bahman Asgharian, Owen Price, Amy Creel, Gladys Erives, Jonathan Fallica, Cissy Li, Nashaat Rasheed, Scott Wasdo, Raymond Yeager, Susan Chemerynski, Jeffry Schroeter
Publikováno v:
Journal of Aerosol Science. 172:106192
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe77f7f2251e0983c1b2bcc5354c80d
https://doi.org/10.1016/j.jaerosci.2023.106192
https://doi.org/10.1016/j.jaerosci.2023.106192
Autor:
Ariane van der Straten, Matthew M. Booth, Scott Wasdo, Daniel Gonzalez, Brian P. Quinn, Timothy E. Morey, Richard J. Melker, Hartmut Derendorf, Donn M. Dennis, Judith Wishin
Publikováno v:
The Journal of Clinical Pharmacology. 53:103-111
Adherence to microbicide gel use is critical to optimizing effectiveness in preventing human immunodeficiency virus transmission. The authors hypothesized that ester taggants added to vaginal gels would generate exhaled alcohol and ketone metabolites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12c938a3ca4e48521700e8e54d95bfcb
https://doi.org/10.1177/0091270011434157
https://doi.org/10.1177/0091270011434157
Publikováno v:
Drug Development and Industrial Pharmacy. 39:1494-1497
The maximum fluxes (J(M)) of nicotinic acid esters (NAE) across silicone membranes from water (J(MPAQ)) have been measured to determine how well they correlate with J(M) of NAE across human skin from water in vitro (J(MHAQ)) and in vivo (J(MHAQ1)) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bcad8b46ea744c2449a77403449e886
https://doi.org/10.3109/03639045.2012.694590
https://doi.org/10.3109/03639045.2012.694590
Publikováno v:
Therapeutic Delivery. 2:83-105
Attempts to deliver drugs into and through the skin (dermal and transdermal delivery) have not been very successful because the physicochemical properties of drugs are often not optimal. Prodrugs can be used to optimize those physicochemical properti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084977642d314b72709339407926d928
https://doi.org/10.4155/tde.10.83
https://doi.org/10.4155/tde.10.83
Publikováno v:
International Journal of Pharmaceutics. 373:62-67
The maximum fluxes of 32 prodrugs and parabens through polydimethylsiloxane membranes from water (EXP log J MPAQ ) have been correlated with the maximum flux of the same prodrugs and parabens through hairless mouse skin from water (EXP log J MMAQ ):
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae73ead61f3b943b969e1175bece55f2
https://doi.org/10.1016/j.ijpharm.2009.02.004
https://doi.org/10.1016/j.ijpharm.2009.02.004
A comparison of the fit of flux through hairless mouse skin from water data to three model equations
Publikováno v:
International Journal of Pharmaceutics. 366:65-73
Data for the delivery of total species containing parent drugs from water through hairless mouse skin by prodrugs, logJ(MMAQ), has been fitted to the Roberts-Sloan, RS, the Kasting-Smith-Cooper, KSC, and Magnusson-Anissimov-Cross-Roberts, MACR, equat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5470ffe3cceba1ce2e41144e75e35920
https://doi.org/10.1016/j.ijpharm.2008.08.045
https://doi.org/10.1016/j.ijpharm.2008.08.045
Autor:
Karen Ulmer, Kenneth B. Sloan, Surjit Singh, Hema Devarajan, Donna Nickels, Scott Wasdo, Juha Juntunen, Thomas L. Murray, Thea Shanks
Publikováno v:
European Journal of Pharmaceutical Sciences. 34:321-332
Do the Roberts–Sloan (RS) or modified Kasting–Smith–Cooper (KSC) equations that provide good fit to data for maximum flux, from water through mouse or human skin also provide a good fit to data for maximum fluxes through silicone membranes (pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d384a3d0209df083f43cc18b1ee991d
https://doi.org/10.1016/j.ejps.2008.05.008
https://doi.org/10.1016/j.ejps.2008.05.008
Publikováno v:
International Journal of Pharmaceutics. 339:157-167
The edited Flynn database (n=62) for determining the effect of the physicochemical properties of solutes on their skin absorption has been extended (n=114) to give a database for which solubilities of the solutes in water, S(AQ), and their maximum fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f6a912a0a532f65b0e44fc14e5feb9
https://doi.org/10.1016/j.ijpharm.2007.02.031
https://doi.org/10.1016/j.ijpharm.2007.02.031
Publikováno v:
Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement ISBN: 9783662450123
A penetration enhancer is by definition anything that is used to improve the delivery of a chemical substance across some biological/biochemical barrier. For the present purposes, we are interested in chemical-, as opposed to, physical-, electrical-,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::348e4af5a96325599b80ab8621d22f99
https://doi.org/10.1007/978-3-662-45013-0_10
https://doi.org/10.1007/978-3-662-45013-0_10
Publikováno v:
Pharmaceutical Research. 23:2729-2747
In theory, topical delivery has substantial potential to treat local and some systemic disease states more effectively than systemic delivery. Unfortunately many, if not most, drug candidates for topical delivery lack the requisite physicochemical pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43277ac01095c9a0742e777f85b2d296
https://doi.org/10.1007/s11095-006-9108-0
https://doi.org/10.1007/s11095-006-9108-0