Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Scott, Norton"'
Autor:
Davide Capauto, Yifan Wang, Feinan Wu, Scott Norton, Jessica Mariani, Fumitaka Inoue, Gregory E. Crawford, Nadav Ahituv, Alexej Abyzov, Flora M. Vaccarino
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Regulation of gene expression through enhancers is one of the major processes shaping the structure and function of the human brain during development. High-throughput assays have predicted thousands of enhancers involved in neurodevelopment
Externí odkaz:
https://doaj.org/article/ca2e76102a6a4aa197468ba562562414
Autor:
M. Scott Norton
The varying concepts of organizational development are relevant to everything done administratively in educational practice. Organizational development centers on the concepts of schools as social organization, and like all other social systems, scho
Autor:
M. Scott Norton
Top-down mandates concerning the curriculum of the school leave no room for program creativity and program commitment. Yet principals and teachers are held accountable for student achievement results. Constitutionally, powers not granted to the Unite
Autor:
M. Scott Norton
The focus of The Legal World of the School Principal is to emphasize the legal responsibilities of the school principal. This book will help principals be knowledgeable of the court cases and federal and state laws that affect their daily work. Resea
Autor:
M. Scott Norton
The primary focus of the book is to emphasize the major changes in the leadership responsibilities of the school principal and to underscore the necessity for them to gain new knowledge and skills in order to direct their leadership toward meeting th
Autor:
Sylvia T Nurnberg, Marie A Guerraty, Robert C Wirka, H Shanker Rao, Milos Pjanic, Scott Norton, Felipe Serrano, Ljubica Perisic, Susannah Elwyn, John Pluta, Wei Zhao, Stephanie Testa, YoSon Park, Trieu Nguyen, Yi-An Ko, Ting Wang, Ulf Hedin, Sanjay Sinha, Yoseph Barash, Christopher D Brown, Thomas Quertermous, Daniel J Rader
Publikováno v:
PLoS Genetics, Vol 16, Iss 1, p e1008538 (2020)
Genome-wide association studies have identified multiple novel genomic loci associated with vascular diseases. Many of these loci are common non-coding variants that affect the expression of disease-relevant genes within coronary vascular cells. To i
Externí odkaz:
https://doaj.org/article/b7dd34ae270f46b99fac5cb149310b65
Autor:
Taejeong, Bae, Liana, Fasching, Yifan, Wang, Joo Heon, Shin, Milovan, Suvakov, Yeongjun, Jang, Scott, Norton, Caroline, Dias, Jessica, Mariani, Alexandre, Jourdon, Feinan, Wu, Arijit, Panda, Reenal, Pattni, Yasmine, Chahine, Rebecca, Yeh, Rosalinda C, Roberts, Anita, Huttner, Joel E, Kleinman, Thomas M, Hyde, Richard E, Straub, Christopher A, Walsh, Alexander E, Urban, James F, Leckman, Daniel R, Weinberger, Flora M, Vaccarino, Sirisha, Pochareddy
Publikováno v:
Science. 377:511-517
We analyzed 131 human brains (44 neurotypical, 19 with Tourette syndrome, 9 with schizophrenia, and 59 with autism) for somatic mutations after whole genome sequencing to a depth of more than 200×. Typically, brains had 20 to 60 detectable single-nu
Autor:
Chengyu Deng, Sean Whalen, Marilyn Steyert, Ryan Ziffra, Pawel F. Przytycki, Fumitaka Inoue, Daniela A. Pereira, Davide Capauto, Scott Norton, Flora M. Vaccarino, Alex Pollen, Tomasz J. Nowakowski, Nadav Ahituv, Katherine S. Pollard
Publikováno v:
bioRxiv
Nucleotide changes in gene regulatory elements are important determinants of neuronal development and disease. Using massively parallel reporter assays in primary human cells from mid-gestation cortex and cerebral organoids, we interrogated thecis-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322fb8de1cb85f6158187c7351e9ce9a
https://europepmc.org/articles/PMC9949039/
https://europepmc.org/articles/PMC9949039/
Autor:
Alexandre Jourdon, Feinan Wu, Jessica Mariani, Davide Capauto, Scott Norton, Livia Tomasini, Anahita Amiri, Milovan Suvakov, Jeremy D. Schreiner, Yeongjun Jang, Arijit Panda, Cindy Khanh Nguyen, Elise M. Cummings, Gloria Han, Kelly Powell, Anna Szekely, James C. McPartland, Kevin Pelphrey, Katarzyna Chawarska, Pamela Ventola, Alexej Abyzov, Flora M. Vaccarino
SummaryThere is no clear genetic etiology or convergent pathophysiology for autism spectrum disorders (ASD). Using cortical organoids and single-cell transcriptomics, we modeled alterations in the formation of the forebrain between sons with idiopath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de719f693357e8358798f4c1bc3bc59e
https://doi.org/10.1101/2022.03.19.484988
https://doi.org/10.1101/2022.03.19.484988
Autor:
Caleb M. Radens, Yoseph Barash, Joseph K. Aicher, Gregory R. Grant, Christopher J Green, Matthew R. Gazzara, Scott Norton, Anupama Jha, Jorge Vaquero-Garcia, Nicholas F. Lahens, Paul Jewell
The ubiquity of RNA-seq has led to many methods that use RNA-seq data to analyze variations in RNA splicing. However, available methods are not well suited for handling heterogeneous and large datasets. Such datasets scale to thousands of samples acr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62d590ec49055db5a2707ff0f893bcc3
https://doi.org/10.1101/2021.11.03.467086
https://doi.org/10.1101/2021.11.03.467086