Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Scott, Kitchen"'
Publikováno v:
Viruses, Vol 16, Iss 2, p 219 (2024)
Chronic Human Immunodeficiency Virus (HIV) infection remains a significant challenge to global public health. Despite advances in antiretroviral therapy (ART), which has transformed HIV infection from a fatal disease into a manageable chronic conditi
Externí odkaz:
https://doaj.org/article/3463a7851743421f9f4edebfdaa793e7
Autor:
Shallu Tomer, Wenli Mu, Gajendra Suryawanshi, Hwee Ng, Li Wang, Wally Wennerberg, Valerie Rezek, Heather Martin, Irvin Chen, Scott Kitchen, Anjie Zhen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cannabis (Cannabis sativa) is a widely used drug in the United States and the frequency of cannabis use is particularly high among people living with HIV (PLWH). One key component of cannabis, the non-psychotropic (−)-cannabidiol (CBD) exerts a wid
Externí odkaz:
https://doaj.org/article/f92e90ed1c9249fcb83d60a6690acfbe
Autor:
Renata Stripecke, Christian Münz, Jan Jacob Schuringa, Karl‐Dimiter Bissig, Brian Soper, Terrence Meeham, Li‐Chin Yao, James P Di Santo, Michael Brehm, Estefania Rodriguez, Anja Kathrin Wege, Dominique Bonnet, Silvia Guionaud, Kristina E Howard, Scott Kitchen, Florian Klein, Kourosh Saeb‐Parsy, Johannes Sam, Amar Deep Sharma, Andreas Trumpp, Livio Trusolino, Carol Bult, Leonard Shultz
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 7, Pp 1-16 (2020)
Abstract Mice xenotransplanted with human cells and/or expressing human gene products (also known as “humanized mice”) recapitulate the human evolutionary specialization and diversity of genotypic and phenotypic traits. These models can provide a
Externí odkaz:
https://doaj.org/article/0b7a5df243a34bd59c1903d19ca29593
Mitoquinone mesylate attenuates brain inflammation in humanized mouse model of chronic HIV infection
Autor:
Sandro Satta, Cristelle Hugo, Madhav Sharma, Valerie Rezek, Athanassios Kossyvakis, Shubhendu Sen Roy, Scott Kitchen, Theodoros Kelesidis
Publikováno v:
AIDS. 36:1609-1611
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8888160e4f6dfc90c1d23a0c2e90681
https://doi.org/10.1097/qad.0000000000003291
https://doi.org/10.1097/qad.0000000000003291
Publikováno v:
Extracellular Vesicles and Circulating Nucleic Acids. 3:118-32
Aim: A peripheral inflammatory response can drive neuroinflammation in a number of infections including human immunodeficiency virus (HIV). Monocyte/macrophage (M/Mφ) activation is a hallmark of acute HIV infection and a source of chronic inflammati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a661c2cd0f1038bc114176d398fb95c
https://doi.org/10.20517/evcna.2022.11
https://doi.org/10.20517/evcna.2022.11
Autor:
Scott Kitchen, Miguel Lizarraga, Heather Martin, Valerie Rezek, Mayra A. Carrillo, Anjie Zhen, Wenli Mu
Publikováno v:
Journal of visualized experiments : JoVE. (188)
The human immunodeficiency virus (HIV-1) pandemic continues to spread unabated worldwide, and currently, there is no vaccine available against HIV. Although combinational antiretroviral therapy (cART) has been successful in suppressing viral replicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d206b57338013376832b5def4c4e7fbc
https://pubmed.ncbi.nlm.nih.gov/36282697
https://pubmed.ncbi.nlm.nih.gov/36282697
Autor:
Anjie Zhen, Scott Kitchen
Publikováno v:
Viruses, Vol 6, Iss 1, Pp 1-12 (2013)
Despite the enormous success of combined anti-retroviral therapy, HIV infection is still a lifelong disease and continues to spread rapidly worldwide. There is a pressing need to develop a treatment that will cure HIV infection. Recent progress in st
Externí odkaz:
https://doaj.org/article/6977232d66324f08a36154344a6a9d64
Autor:
Anjie Zhen, Wenli Mu, Valerie Rezek, Heather Martin, Mayra Carrillo, Philip Hamid, Miguel Lizarraga, Otto Yang, Beth Jamieson, Scott Kitchen
Publikováno v:
The Journal of Immunology. 208:182.33-182.33
A hallmark of HIV-1 infection is chronic inflammation. Chronic immune activation drives the pathogenesis of HIV-1 infection, leading to loss of CD4+ T cells and immune exhaustion. Previously, we demonstrated that persistent type I interferon (IFN-I)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dd3c87ce5ad52284aeb3e7a754e4aa0
https://doi.org/10.4049/jimmunol.208.supp.182.33
https://doi.org/10.4049/jimmunol.208.supp.182.33
Autor:
Shallu Tomer, Wenli Mu, Hwee Ng, Li Wang, Wally Wennerberg, Valerie Razek, Heather Martin, Anjie Zhen, Scott Kitchen
Publikováno v:
The Journal of Immunology. 208:111.16-111.16
Methods THP-1 and HMC3 cells were exposed to CBD/vehicle with and without stimulation with 2’3'-cGAMP (cGAMP), LPS, or PMA/ionomycin. qPCR was carried out to investigate the expression of interferon stimulatory genes (ISGs). RNA-Seq was performed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d75b8fc25115e130dc9aa759ea0bd47
https://doi.org/10.4049/jimmunol.208.supp.111.16
https://doi.org/10.4049/jimmunol.208.supp.111.16
Publikováno v:
Bio-Protocol, Vol 3, Iss 4 (2013)
The NSG-CTL mouse model is a humanized mouse model that allows the generation of peripheral human immune responses, particularly CD8+ Cytotoxic T lymphocyte (CTL) responses, and serves as an effective model for studying gene-based therapies. Natural
Externí odkaz:
https://doaj.org/article/4f0e3e2807e7482f8394a47a232985fc