Adam Naming the Animals.

Autor: Jean, Gérard, Scotin, Baptiste, Cole, James

Publikováno v: Arts & Activities. Nov2018, Vol. 164 Issue 3, p37-37. 1p. 1 Black and White Photograph.

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Scotin: A new p63 target gene expressed during epidermal differentiation

Autor: Gerry Melino, Jean-Christophe Bourdon, Andrea Codispoti, Loredana Zocchi, David P. Lane, Richard A. Knight, Alessandro Terrinoni

Publikováno v: Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, 2008, 367 (2), pp.271-6. ⟨10.1016/j.bbrc.2007.12.115⟩

International audience; p63, a member of the p53 family, is transcribed from two different promoters giving rise to two different proteins: TAp63 that contains the N-terminal transactivation domain and DeltaN that lacks this domain. In this article w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fab4af429a340966823dc98041baa5

Mechanism of Induction of Apoptosis by p73 and Its Relevance to Neuroblastoma Biology

Autor: Gerry Melino, Alessandro Terrinoni, Richard A. Knight, A. Emre Sayan, Mario Rossi

Publikováno v: Annals of the New York Academy of Sciences. 1028:143-149

TP73, as a TP53 homologue, drew the attention of tumor biologists because it is rarely mutated in human cancers and can induce cell cycle arrest and apoptosis by activating genes also regulated by p53. However, TP73 harbors an additional promoter tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9780aa31f35d620d5320821901110706
https://doi.org/10.1196/annals.1322.015

The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane

Autor: Ingrid Dræby, Martin W. Berchtold, Jens Mollerup, Jonas M. la Cour, Jean-Christophe Bourdon, Yvonne L. Woods

Publikováno v: Archives of Biochemistry and Biophysics
Archives of Biochemistry and Biophysics, 2007, 467 (1), pp.87-94. ⟨10.1016/j.abb.2007.07.028⟩

International audience; ALG-2 (apoptosis linked gene 2 product) is a calcium binding protein for which no clear cellular function has been established. In this study we identified Scotin as a novel ALG-2 target protein containing 6 PXY and 4 PYP repe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b0f4172453db08634a1c0f779e8305
https://www.hal.inserm.fr/inserm-00409606