Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Scot P. Ouellette"'
Autor:
Natalie A. Sturd, Lindsey A. Knight, Macy G. Wood, Legacy Durham, Scot P. Ouellette, Elizabeth A. Rucks
Publikováno v:
mSphere, Vol 9, Iss 11 (2024)
ABSTRACT The obligate intracellular pathogen, Chlamydia trachomatis, establishes an intracellular niche within a host membrane-derived vacuole called the chlamydial inclusion. From within this inclusion, C. trachomatis orchestrates numerous host-path
Externí odkaz:
https://doaj.org/article/b5d4eff104fb42f6b52026b92e6203a3
Autor:
Niaz Bahar Chowdhury, Nick Pokorzynski, Elizabeth A. Rucks, Scot P. Ouellette, Rey A. Carabeo, Rajib Saha
Publikováno v:
mSystems, Vol 9, Iss 7 (2024)
ABSTRACT Upon nutrient starvation, Chlamydia trachomatis serovar L2 (CTL) shifts from its normal growth to a non-replicating form, termed persistence. It is unclear if persistence reflects an adaptive response or a lack thereof. To understand this, t
Externí odkaz:
https://doaj.org/article/dfd1bbcefc024bc2b2792b40e2f64df2
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Chlamydia trachomatis is an obligate intracellular bacterium that is responsible for the most prevalent bacterial sexually transmitted infection. Changes in DNA topology in this pathogen have been linked to its pathogenicity-associated devel
Externí odkaz:
https://doaj.org/article/0c78de46747546efb06f638a6d1d49a9
Autor:
Nathan D. Hatch, Scot P. Ouellette
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Chlamydia trachomatis is a developmentally regulated, obligate intracellular bacterium that encodes three sigma factors: σ66, σ54, and σ28. σ66 is the major sigma factor controlling most transcription initiation during early- and mid-cyc
Externí odkaz:
https://doaj.org/article/da4e63aa765e40a1a3b8f10b95659b56
Autor:
Gilbert Greub, Trestan Pillonel, Patrik M. Bavoil, Nicole Borel, Lee Ann Campbell, Deborah Dean, Scott Hefty, Matthias Horn, Servaas A. Morré, Scot P. Ouellette, Yvonne Pannekoek, Mirja Puolakkainen, Peter Timms, Raphael Valdivia, Daisy Vanrompay
Publikováno v:
New Microbes and New Infections, Vol 54, Iss , Pp 101158- (2023)
The International Committee on Systematics of Prokaryotes (ICSP) discussed and rejected in 2020 a proposal to modify the International Code of Nomenclature of Prokaryotes to allow the use of gene sequences as type for naming prokaryotes. An alternati
Externí odkaz:
https://doaj.org/article/5f80302dc2134266bbb63d3db0ef7490
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
In adapting to the intracellular niche, obligate intracellular bacteria usually undergo a reduction of genome size by eliminating genes not needed for intracellular survival. These losses can include, for example, genes involved in nutrient anabolic
Externí odkaz:
https://doaj.org/article/cc7dd8bef4ad471f8134146a6b880199
Autor:
Stefan Pan, Aaron A. Jensen, Nicholas A. Wood, Beate Henrichfreise, Heike Brötz-Oesterhelt, Derek J. Fisher, Peter Sass, Scot P. Ouellette
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Bacterial AAA+ unfoldases are crucial for bacterial physiology by recognizing specific substrates and, typically, unfolding them for degradation by a proteolytic component. The caseinolytic protease (Clp) system is one example where a hexame
Externí odkaz:
https://doaj.org/article/857aa81bf9db41a79d73ef9b1e32e438
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Despite having a highly reduced genome, Chlamydia trachomatis undergoes a complex developmental cycle in which the bacteria differentiate between the following two functionally and morphologically distinct forms: the infectious, nonreplicati
Externí odkaz:
https://doaj.org/article/f78e79de54ad414d84d16f9d4e2e471a
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Chlamydia trachomatis does not possess TrpL-mediated transcription attenuation of its trp operon. Here, the authors show that an iron-dependent regulator, YtgR, acts as a tryptophan-dependent attenuator of the trp operon in this organism, due to tran
Externí odkaz:
https://doaj.org/article/1d61775e0be44d8a805cabbaa95c91c5
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
ABSTRACT Chlamydia trachomatis and Streptococcus pyogenes are among the most prevalent bacterial pathogens of humans. Interestingly, both pathogens are tryptophan (Trp) auxotrophs and must acquire this essential amino acid from their environment. For
Externí odkaz:
https://doaj.org/article/79f105ed086a43e586063f1ee20ec55b