Distinct impacts of each anti-anti-sigma factor ortholog of the chlamydial Rsb partner switching mechanism on development in Chlamydia trachomatis

Autor: Shiomi Junker, Vandana Singh, Aamal G. M. Al-Saadi, Nicholas A. Wood, Scott D. Hamilton-Brehm, Scot P. Ouellette, Derek J. Fisher

Publikováno v: Microbiology Spectrum, Vol 12, Iss 12 (2024)

ABSTRACT Partner switching mechanisms (PSMs) are signal transduction systems comprised of a sensor phosphatase (RsbU), an anti-sigma factor (RsbW, kinase), an anti-anti-sigma factor (RsbV, the RsbW substrate), and a target sigma factor. Chlamydia spp

Externí odkaz: https://doaj.org/article/c5f15045f9284906857f1015cd2cdb2b

Chlamydia trachomatis Inc Ct226 is vital for FLI1 and LRRF1 recruitment to the chlamydial inclusion

Autor: Natalie A. Sturd, Lindsey A. Knight, Macy G. Wood, Legacy Durham, Scot P. Ouellette, Elizabeth A. Rucks

Publikováno v: mSphere, Vol 9, Iss 11 (2024)

ABSTRACT The obligate intracellular pathogen, Chlamydia trachomatis, establishes an intracellular niche within a host membrane-derived vacuole called the chlamydial inclusion. From within this inclusion, C. trachomatis orchestrates numerous host-path

Externí odkaz: https://doaj.org/article/b5d4eff104fb42f6b52026b92e6203a3

Evidence from comprehensive independent validation studies for smooth pursuit dysfunction as a sensorimotor biomarker for psychosis

Autor: Inga Meyhoefer, Andreas Sprenger, David Derad, Dominik Grotegerd, Ramona Leenings, Elisabeth J. Leehr, Fabian Breuer, Marian Surmann, Karen Rolfes, Volker Arolt, Georg Romer, Markus Lappe, Johanna Rehder, Nikolaos Koutsouleris, Stefan Borgwardt, Frauke Schultze-Lutter, Eva Meisenzahl, Tilo T. J. Kircher, Sarah S. Keedy, Jeffrey R. Bishop, Elena I. Ivleva, Jennifer E. McDowell, James L. Reilly, Scot Kristian Hill, Godfrey D. Pearlson, Carol A. Tamminga, Matcheri S. Keshavan, Elliot S. Gershon, Brett A. Clementz, John A. Sweeney, Tim Hahn, Udo Dannlowski, Rebekka Lencer

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Abstract Smooth pursuit eye movements are considered a well-established and quantifiable biomarker of sensorimotor function in psychosis research. Identifying psychotic syndromes on an individual level based on neurobiological markers is limited by h

Externí odkaz: https://doaj.org/article/b0e9c9d4124c438f8e19e27317493ebc

Physical space of thirty pediatric intensive care units in the United States of America: a national survey

Autor: Oliver Karam, Aziez Ahmed, Matthew Bizzarro, Clifford Bogue, John S. Giuliano, PICU Space Collaborative, Awni Al-Subu, Scot Bateman, Eric Berning, Kyle Brown, Yonca Bulut, Ira M. Cheifetz, Madhuradhar Chegondi, Jill Cholette, Allison Cowl, Gary Ceneviva, Jon Gehlbach, Michael Hobson, Sapna R. Kudchadkar, Sonia Labarinas, Cassandra L. Louis, Michael Miller, Mark Marinello, Matthew P Malone, Alison Nair, Akira Nishisaki, Lia Lowrie, Kyle Rehder, Ranna Rozenfeld, James Schneider, Jake Sequeira, Steven L. Shein, Erika Stalets, John Taylor, Phoebe Yager

Publikováno v: Frontiers in Pediatrics, Vol 12 (2024)

IntroductionThe design of Pediatric Intensive Care Unit (PICU) rooms significantly impacts patient care and satisfaction. The aims were first, to describe the current physical space across PICUs in the USA, and second, to identify what proportion of

Externí odkaz: https://doaj.org/article/11674b9317dd4335a68419528d55d2ba

A summary of the main themes and findings presented at the ASM Intermountain Branch meeting (2024)

Autor: Jay Radke, Javier Ochoa-Repåraz, Jamee Nixon, Sajal Acharya, Haley Bridgewater, Joshua Burger, Abigail Cheever, Robert Darby, William Doyle, Alka Gaur, Eva Githuku, Rose Goodman, Topher Haynie, Hannah Hedelius, Kristina Hill, Misha Iqbal, Salma Laabi, Carlos Moreno, Melinda Moss, Nagama Parveen, Naomi Rapier-Sharman, Sara Sadeghi, Saeed Saleh, Sean Schumacher, Miranda Sharp, Noah Souza, Soni Thapa, Shule Aggabao, David Amsbury, Sheena Isabelle Bautista, Atalie Bogh, Aaron Bohn, Cade Brink, B. Shaun Bryner, James Cannon, Scot Carrington, Hayzen Chamberlain, Alex Cherry, McKaylin Cole, Edgar Corrales, Caz Cullimore, Sophie Daines, Payson Danielson, Monterey Domike, Matthew East, Bronwyn Ellis, Taryn Evans, Zach Fears, Paige Fellars, Tate Fisher, Braxton Floyd, Trenton Gibson, Mason Gueller, Heather Gupta, Jacob Gwilliam, Mackenzie Hansen, Jacob Hardy, Christopher Harrell, Rebecca Hassell, Wesley Hendricks, Colby Hendrix, Hirsche Henstrom, Kelly Hernandez Sanguino, George Higgins, Hyunbi Hwang, Matt Jackson, Conner Jensen, Austin Johnson, Chloe Kang, Sehi Kim, Alexandra LaFollette, Phoenix Larsen, Abbey Larson, Bryson Leary, Jayden Longhurst, Michael Mann, Isreal Martinez, Brooklyn Matthews, Cody McStraw, Ninahazwe Mireill, Rachel Moffat, Peter Mourik, Madelyn Mudrow, Mailon Odell, Blake Oler, Natalie Olsen, Nazanin Paymard, Spencer T. Payne, Levi Pearson, Josh Peter, Tiffani Peterson, Daniel Puentes Navarro, Kyla Radke, Joseph Richardson, Russell Ridd, Akir Rowe, Rylan Schmanski, Jacob Scott, Samuel Scott, Mya Simpkins, Madalyne Sisk, Tyler Smith, Brinley Smith, Jacob Sy, Gisselle Trejo, Bartel Van Oostendorp, Ethan Walbom, Rebecca Whetten, Dallin Zollinger, Miriam Braunstein, Donald P. Breakwell, Anirban Chakraborty, Matthew Crook, Michele Culumber, Wayne Hatch, Victor M. Jimenez, Jr., Wales P. Nematollahi, Michael Olson, Mark Poritz, Seth Ririe, Jeffrey Schachterle, Lisa Wiltbank, Todd Kelson, Brett E. Pickett

Publikováno v: mSphere, Vol 9, Iss 7 (2024)

ABSTRACT The annual meeting for the Intermountain Branch was held in April 2024 on the campus of Brigham Young University. There were 127 branch members from Utah, Idaho, and Nevada who attended the meeting and were composed of undergraduate students

Externí odkaz: https://doaj.org/article/37d271f25abc49d3ae9d6985f02e4fc2