Zobrazeno 1 - 3
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pro vyhledávání: '"Scola Paula M"'
Publikováno v:
Tetrahedron Letters. 33:1557-1560
The left halves of norhalichondrins and homohalichondrins were synthesized from γ-lactone 1, readily available from D-galactose glycal via Ireland-Claisen rearrangement then iodolactonization.
Autor:
Yoshito Kishi, Suk Kyoon Yoon, Keith R. Buszek, Craig J. Forsyth, Scola Paula M, Francis G. Fang, Sung Ho Jung
Publikováno v:
Tetrahedron Letters. 33:1553-1556
Autor:
Scola Paula M, Francis G. Fang, Yoshito Kishi, Craig J. Forsyth, Keith R. Buszek, Thomas Daniel Aicher, Sun Ho Jung
Publikováno v:
Tetrahedron Letters. 33:1549-1552
An efficient synthesis of the C.27–C.38 segment of halichondrins is accomplished, using the Ireland-Claisen rearrangement, Ni(II)/Cr(II)-mediated coupling and Michael reactions as the key steps.