Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-Modified T-Cell Therapy Recipient: A Case Study.

Autor: Hensley MK; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Bain WG; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, USA., Jacobs J; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Nambulli S; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Parikh U; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Cillo A; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Tumor Microenvironment Center, Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA., Staines B; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Heaps A; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Sobolewski MD; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Rennick LJ; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Macatangay BJC; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Klamar-Blain C; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Kitsios GD; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Methé B; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Somasundaram A; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Division of Hematology, Oncology, Department of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA., Bruno TC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Cardello C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Shan F; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Workman C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Ray P; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Ray A; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Lee J; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Sethi R; Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Schwarzmann WE; Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Ladinsky MS; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA., Bjorkman PJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA., Vignali DA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Duprex WP; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Agha ME; Division of Hematology, Oncology, Department of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA., Mellors JW; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., McCormick KD; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Morris A; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Haidar G; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2021 Aug 02; Vol. 73 (3), pp. e815-e821.

Differential gene expression in peripheral blood mononuclear cells from children immunized with inactivated influenza vaccine.

Autor: Alcorn JF; Department of Pediatrics, University of Pittsburgh , Pittsburgh, PA, USA., Avula R; Department of Biomedical Informatics, University of Pittsburgh , Pittsburgh, PA, USA., Chakka AB; Department of Biomedical Informatics, University of Pittsburgh , Pittsburgh, PA, USA., Schwarzmann WE; Department of Biomedical Informatics, University of Pittsburgh , Pittsburgh, PA, USA., Nowalk MP; Department of Family Medicine, University of Pittsburgh , Pittsburgh, PA, USA., Lin CJ; Department of Family Medicine, University of Pittsburgh , Pittsburgh, PA, USA., Ortiz MA; Department of Pediatrics, University of Pittsburgh , Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh , Pittsburgh, PA, USA., Horne WT; Department of Pediatrics, University of Pittsburgh , Pittsburgh, PA, USA., Chandran UR; Department of Biomedical Informatics, University of Pittsburgh , Pittsburgh, PA, USA., Nagg JP; Department of Pediatrics, University of Pittsburgh , Pittsburgh, PA, USA., Zimmerman RK; Department of Family Medicine, University of Pittsburgh , Pittsburgh, PA, USA., Cole KS; Center for Vaccine Research, University of Pittsburgh , Pittsburgh, PA, USA., Moehling KK; Department of Family Medicine, University of Pittsburgh , Pittsburgh, PA, USA., Martin JM; Department of Pediatrics, University of Pittsburgh , Pittsburgh, PA, USA.

Publikováno v: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2020 Aug 02; Vol. 16 (8), pp. 1782-1790. Date of Electronic Publication: 2020 Apr 16.