Calorie restriction improves metabolic state independently of gut microbiome composition: a randomized dietary intervention trial

Autor: Sowah, Solomon A, Milanese, Alessio, Schübel, Ruth, Wirbel, Jakob, Kartal, Ece, Johnson, Theron S, Hirche, Frank, Grafetstätter, Mirja, Nonnenmacher, Tobias, Kirsten, Romy, López-Nogueroles, Marina, Lahoz, Agustín, Schwarz, Kathrin V, Okun, Jürgen G, Ulrich, Cornelia M, Nattenmüller, Johanna, von Eckardstein, Arnold, Müller, Daniel, Stangl, Gabriele I, Kaaks, Rudolf, Kühn, Tilman, Zeller, Georg

Publikováno v: Sowah, S A, Milanese, A, Schübel, R, Wirbel, J, Kartal, E, Johnson, T S, Hirche, F, Grafetstätter, M, Nonnenmacher, T, Kirsten, R, López-Nogueroles, M, Lahoz, A, Schwarz, K V, Okun, J G, Ulrich, C M, Nattenmüller, J, von Eckardstein, A, Müller, D, Stangl, G I, Kaaks, R, Kühn, T & Zeller, G 2022, ' Calorie restriction improves metabolic state independently of gut microbiome composition: a randomized dietary intervention trial ', genome medicine, vol. 14, 30 . https://doi.org/10.1186/s13073-022-01030-0
Genome Medicine
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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Background The gut microbiota has been suggested to play a significant role in the development of overweight and obesity. However, the effects of calorie restriction on gut microbiota of overweight and obese adults, especially over longer durations,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f0026ad1356d126c3f68a335b9f5aa
https://doi.org/10.1186/s13073-022-01030-0

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Dietary stearic acid regulates mitochondria in vivo in humans

Autor: Senyilmaz-Tiebe, Deniz, Pfaff, Daniel H, Virtue, Sam, Schwarz, Kathrin V, Fleming, Thomas, Altamura, Sandro, Muckenthaler, Martina U, Okun, Jürgen G, Vidal-Puig, Antonio, Nawroth, Peter, Teleman, Aurelio A

Since modern foods are unnaturally enriched in single metabolites, it is important to understand which metabolites are sensed by the human body and which are not. We previously showed that the fatty acid stearic acid (C18:0) signals via a dedicated p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4bf3d7c10cb71ec5e8404f5c4e6c61cb