Výsledky vyhledávání - "Schwartz, Jc"

4-(ω-(Alkyloxy)alkyl)-1H-imidazole Derivatives as Histamine H3 Receptor Antagonists/Agonists

Autor: C. Robin Ganellin, Heinz H. Pertz, Michael Krause, Holger Stark, Schwartz Jc, A Huls, X Ligneau, Jean-Michel Batiment Arrang, W Schunack, Galina Meier

Publikováno v: Journal of Medicinal Chemistry. 47:2678-2687

In an effort to develop new histamine H(3) receptor antagonists usable as pharmacological tools we present here novel unsymmetrical ether derivatives. Etherification of different omega-(1H-imidazol-4-yl)alkyl scaffolds led to compounds containing alk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743fba750a413ecf8328fe8244e11b39
https://doi.org/10.1021/jm031065q

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A DOSE OF REALITY FOR MEDICAL MALPRACTICE REFORM

Autor: Schwartz, JC

Publikováno v: NEW YORK UNIVERSITY LAW REVIEW, vol 88, iss 4
Schwartz, JC. (2013). A DOSE OF REALITY FOR MEDICAL MALPRACTICE REFORM. NEW YORK UNIVERSITY LAW REVIEW, 88(4), 1224-1307. UCLA: Retrieved from: http://www.escholarship.org/uc/item/4965r0dj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9500ab5ca1360c8d28fdac5f92a547f1
https://escholarship.org/uc/item/4965r0dj

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Design of Potent Non-Thiourea H3-Receptor Histamine Antagonists

Autor: M. Garbarg, Schwartz Jc, Y. S. Khalaf, X. Ligneau, W. Tertiuk, J.‐M. Arrang, S. K. Hosseini, Charon Robin Ganellin

Publikováno v: Journal of Medicinal Chemistry. 38:3342-3350

Starting from thioperamide, the first potent and selective H 3 -receptor histamine antagonist, analogues have been synthesized and tested in vitro on rat cerebral cortex to explore structure-activity relationships. The aim has been to design potent c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e770fa7029b495e58f5fc3ede1e5147
https://doi.org/10.1021/jm00017a018

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ChemInform Abstract: A Novel Series of (Phenoxyalkyl)imidazoles as Potent H3-Receptor Histamine Antagonists

Autor: Garbarg M, W. Tertiuk, Charon Robin Ganellin, Athmani S, A. Fkyerat, Benny Bang-Andersen, Schwartz Jc, X Ligneau

Publikováno v: ChemInform. 28

[[(4-Nitrophenyl)X]alkyl]imidazole isosteres (where X = NH, S, CH2S, O) of previously described [[(5-nitropyrid-2-yl)X]ethyl]imidazoles (where X = NH, S) have been synthesized and evaluated for H3-receptor histamine antagonism in vitro (Ki for [3H]hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72ce2b5c61420cfa411b847f19bed17f
https://doi.org/10.1002/chin.199703168

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