FTY720 (Fingolimod) has an antiproliferative effect on human Glioblastoma cells alone and in combination with Temozolomide but does not influence the expression of EMT-related genes

Autor: Gött, H, Nagl, J, Santhiyanesan, S, Seemann, C, Schwarm, FP, Uhl, E, Stein, M, Kolodziej, MA

Publikováno v: 73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCV082 /20220525/

Objective: FTY720 as immunomodulative drug has also an impact on cell signaling pathways involved in cell proliferation and survival, and several studies suggest an effect on epithelial to mesenchymal transition (EMT) pathways. In this study we inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a52b3b54294f1ce13509686795264dc

Long-term follow up after shunt surgery for normal pressure hydrocephalus – an analysis of symptom progression, Evan’s index and optimal VP-shunt settings

Autor: Gencer, AH, Schwarm, FP, Nagl, J, Uhl, E, Kolodziej, MA

Publikováno v: 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie; 20210606-20210609; sine loco [digital]; DOCP206 /20210604/

Objective: Ventriculoperitoneal (VP) shunt implantation is a well-established treatment method for patients with normal pressure hydrocephalus (NPH). This retrospective study aims to investigate the effects of this type of surgery on patients in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae384482bcdb01c34e25299ebe789c0

Comparison of neurosurgical interventions after fetoscopic prenatal and microsurgical postnatal coverage of spina bifida aperta

Autor: Kolodziej, M, Schwarm, FP, Graf, K, Ehrhardt, H, Stein, M, Neubarer, BA, Uhl, E

Publikováno v: 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie; 20190512-20190515; Würzburg; DOCV026 /20190508/

Objective: To evaluate the need for secondary neurosurgical intervention after fetoscopic and postnatal microsurgical coverage of spina bifida aperta (SBA). We evaluated also the wound infection as a role of surgical timing after SBA repair in the se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec6e80ad1ec06c4f7b99de582323a01

Significantly higher expression of high-mobility group AT hook protein 2 (HMGA2) in the border zone of glioblastoma.

Autor: Nohman AI; Department of Neurosurgery, Justus-Liebig University Giessen, Giessen, Germany - amin.nohman@med.uni-heidelberg.de.; Unit of Experimental Neurosurgery, Department of Neurosurgery, Ruprecht Karl University Hospital of Heidelberg, Heidelberg, Germany - amin.nohman@med.uni-heidelberg.de., Schwarm FP; Department of Neurosurgery, Justus-Liebig University Giessen, Giessen, Germany., Stein M; Department of Neurosurgery, Justus-Liebig University Giessen, Giessen, Germany., Schänzer A; Department of Neuropathology, Justus-Liebig University Giessen, Giessen, Germany., Koch C; Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Justus-Liebig University Giessen, Giessen, Germany., Uhl E; Department of Neurosurgery, Justus-Liebig University Giessen, Giessen, Germany., Kolodziej M; Department of Neurosurgery, Justus-Liebig University Giessen, Giessen, Germany.

Publikováno v: Journal of neurosurgical sciences [J Neurosurg Sci] 2024 Dec; Vol. 68 (6), pp. 668-675. Date of Electronic Publication: 2023 Mar 29.

Does lumbar spinal decompression or fusion surgery influence outcome parameters in patients with intrathecal morphine treatment for persistent spinal pain syndrome type 2 (PSPS-T2).

Autor: Schwarm FP; Department of Neurosurgery, Justus-Liebig-University Giessen, Giessen, Germany., Rehman R; Department of Neurosurgery Hospital Darmstadt, Darmstadt, Germany., Nagl J; Department of Neurosurgery, Justus-Liebig-University Giessen, Giessen, Germany., Gött H; Department of Neurosurgery, Justus-Liebig-University Giessen, Giessen, Germany., Uhl E; Department of Neurosurgery, Justus-Liebig-University Giessen, Giessen, Germany., Kolodziej MA; Department of Neurosurgery, Justus-Liebig-University Giessen, Giessen, Germany.

Publikováno v: Scandinavian journal of pain [Scand J Pain] 2023 Sep 06; Vol. 23 (4), pp. 677-686. Date of Electronic Publication: 2023 Sep 06 (Print Publication: 2023).