Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Schwalfenberg, M"'
Autor:
Ceballos, J, Schwalfenberg, M, Karageorgis, G, Reckzeh, ES, Sievers, S, Ostermann, C, Pahl, A, Sellstedt, M, Nowacki, J, Carnero Corrales, MA, Wilke, J, Laraia, L, Tschapalda, K, Metz, M, Sehr, DA, Brand, S, Winklhofer, K, Janning, P, Ziegler, S, Waldmann, H
Bioactive compound design based on natural product (NP) structure may be limited due to partial coverage of NP‐like chemical space and biological target space. These limitations can be overcome by combining NP‐centered strategies with fragment‐
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::be1f36eb2f87b0a1ff40e0a0e64c39ed
https://eprints.whiterose.ac.uk/151777/1/anie.201909518.pdf
https://eprints.whiterose.ac.uk/151777/1/anie.201909518.pdf
Autor:
Kläsener, Kathrin1,2 (AUTHOR), Herrmann, Nadja1,3 (AUTHOR), Håversen, Liliana4 (AUTHOR), Sundell, Timothy3 (AUTHOR), Sundqvist, Martina3 (AUTHOR), Lundqvist, Christina3 (AUTHOR), Manna, Paul T5 (AUTHOR), Jonsson, Charlotte A3 (AUTHOR), Visentini, Marcella6 (AUTHOR), Ljung Sass, Diana7 (AUTHOR), McGrath, Sarah3 (AUTHOR), Grimstad, Kristoffer3,8 (AUTHOR), Aranburu, Alaitz3 (AUTHOR), Mellgren, Karin7 (AUTHOR), Fogelstrand, Linda9,10 (AUTHOR), Forsman, Huamei3 (AUTHOR), Ekwall, Olov3,11 (AUTHOR), Borén, Jan4 (AUTHOR), Gjertsson, Inger3,12 (AUTHOR), Reth, Michael1,2 (AUTHOR)
Publikováno v:
Clinical & Translational Immunology. 2024, Vol. 13 Issue 10, p1-17. 17p.
Autor:
Cortes Ballen, Ashley Irin1 (AUTHOR), Amosu, Maryam1 (AUTHOR), Ravinder, Surya1 (AUTHOR) acortes3@jhu.edu, Chan, Joey1 (AUTHOR), Derin, Emre1 (AUTHOR), Slika, Hasan1 (AUTHOR), Tyler, Betty1 (AUTHOR) btyler@jhmi.edu
Publikováno v:
Cells (2073-4409). Sep2024, Vol. 13 Issue 18, p1574. 30p.
Autor:
Gupta, Ishita1,2 (AUTHOR), Badrzadeh, Fariba1,2 (AUTHOR), Tsentalovich, Yuri3 (AUTHOR), Gaykalova, Daria A.1,2,4,5 (AUTHOR) dgaykalova@som.umaryland.edu
Publikováno v:
Journal of Experimental & Clinical Cancer Research (17569966). 8/21/2024, Vol. 43 Issue 1, p1-32. 32p.
Autor:
Ceballos J; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Current address: Laboratory of Catalysis and Organic Synthesis, EPFL SB ISIC LCSO, BCH 4221, 1015, Lausanne, Switzerland., Schwalfenberg M; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Karageorgis G; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Current address: School of Chemistry, University of Leeds, Leeds, LS2 9JT, UK., Reckzeh ES; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Faculty of Chemistry and Chemical Biology, Technical University Dortmund, Otto-Hahn-Strasse 6, 44227, Dortmund, Germany., Sievers S; Compound Management and Screening Center, Dortmund, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Ostermann C; Compound Management and Screening Center, Dortmund, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Pahl A; Compound Management and Screening Center, Dortmund, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Sellstedt M; Department of Chemistry, Umeå University, 901 87, Umeå, Sweden.; Current address: Clinical Chemistry, Laboratory Medicine, University Hospital of Umeå, 901 85, Umeå, Sweden., Nowacki J; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Carnero Corrales MA; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Wilke J; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Faculty of Chemistry and Chemical Biology, Technical University Dortmund, Otto-Hahn-Strasse 6, 44227, Dortmund, Germany., Laraia L; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Current address: Department of Chemistry, Technical University of Denmark, Kemitorvet, Bygning 207, 2800, Kgs Lyngby, Denmark., Tschapalda K; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Metz M; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Sehr DA; Department of Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, 44801, Bochum, Germany., Brand S; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Winklhofer K; Department of Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, 44801, Bochum, Germany., Janning P; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Ziegler S; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Waldmann H; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Faculty of Chemistry and Chemical Biology, Technical University Dortmund, Otto-Hahn-Strasse 6, 44227, Dortmund, Germany.
Publikováno v:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2019 Nov 18; Vol. 58 (47), pp. 17016-17025. Date of Electronic Publication: 2019 Oct 07.
Autor:
Reckzeh ES; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany; Technical University Dortmund, Faculty of Chemistry and Chemical Biology, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany., Karageorgis G; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Schwalfenberg M; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Ceballos J; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Nowacki J; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Stroet MCM; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Binici A; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Knauer L; Technical University Dortmund, Faculty of Chemistry and Chemical Biology, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany., Brand S; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Choidas A; Lead Discovery Center GmbH, Otto-Hahn-Strasse 15, 44227 Dortmund, Germany., Strohmann C; Technical University Dortmund, Faculty of Chemistry and Chemical Biology, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany., Ziegler S; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Waldmann H; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany; Technical University Dortmund, Faculty of Chemistry and Chemical Biology, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany. Electronic address: herbert.waldmann@mpi-dortmund.mpg.de.
Publikováno v:
Cell chemical biology [Cell Chem Biol] 2019 Sep 19; Vol. 26 (9), pp. 1214-1228.e25. Date of Electronic Publication: 2019 Jul 11.
Autor:
Karageorgis G; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany., Reckzeh ES; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany.; Technische Universität Dortmund, Fakultät Chemie, Lehrbereich Chemische Biologie, Dortmund, Germany., Ceballos J; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany.; Technische Universität Dortmund, Fakultät Chemie, Lehrbereich Chemische Biologie, Dortmund, Germany., Schwalfenberg M; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany.; Technische Universität Dortmund, Fakultät Chemie, Lehrbereich Chemische Biologie, Dortmund, Germany., Sievers S; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany.; Compound Management and Screening Center, Dortmund, Germany., Ostermann C; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany.; Compound Management and Screening Center, Dortmund, Germany., Pahl A; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany.; Compound Management and Screening Center, Dortmund, Germany., Ziegler S; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany., Waldmann H; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany. herbert.waldmann@mpi-dortmund.mpg.de.; Technische Universität Dortmund, Fakultät Chemie, Lehrbereich Chemische Biologie, Dortmund, Germany. herbert.waldmann@mpi-dortmund.mpg.de.
Publikováno v:
Nature chemistry [Nat Chem] 2018 Nov; Vol. 10 (11), pp. 1103-1111. Date of Electronic Publication: 2018 Sep 10.
Autor:
Jayathilake, Pahala Gedara1 (AUTHOR) Jayathilake.pahalagedara@oncology.ox.ac.uk, Victori, Pedro1 (AUTHOR), Pavillet, Clara E.2 (AUTHOR), Lee, Chang Heon1 (AUTHOR), Voukantsis, Dimitrios1 (AUTHOR), Miar, Ana1 (AUTHOR), Arora, Anjali1 (AUTHOR), Harris, Adrian L.1 (AUTHOR), Morten, Karl J.3 (AUTHOR), Buffa, Francesca M.1,4 (AUTHOR) Jayathilake.pahalagedara@oncology.ox.ac.uk
Publikováno v:
PLoS Computational Biology. 3/15/2024, Vol. 20 Issue 3, p1-29. 29p.
Autor:
Sun, Xin-Yi1,2,3,4 (AUTHOR), Xiao, Mian4 (AUTHOR), Fu, Min4 (AUTHOR), Gao, Qian4 (AUTHOR), Li, Rui-Feng4 (AUTHOR), Wang, Jing4 (AUTHOR), Li, Sheng-Lin1,2,3,4 (AUTHOR), Ge, Xi-Yuan1,2,3,4 (AUTHOR) gexiyuan@bjmu.edu.cn
Publikováno v:
Biomolecules (2218-273X). Mar2024, Vol. 14 Issue 3, p266. 20p.
Autor:
Picard, Lea Katharina1 (AUTHOR) lea.picard@uk-koeln.de, Niemann, Jens Alexander1 (AUTHOR) niemann@ifado.de, Littwitz-Salomon, Elisabeth2 (AUTHOR) elisabeth.littwitz@uni-due.de, Waldmann, Herbert3,4 (AUTHOR) herbert.waldmann@mpi-dortmund.mpg.de, Watzl, Carsten1 (AUTHOR) watzl@ifado.de
Publikováno v:
International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 5, p2917. 16p.