Deconstructing Intratumoral Heterogeneity through Multiomic and Multiscale Analysis of Serial Sections.

Autor: Schupp, Patrick G.^1,2 (AUTHOR) pschupp@sonic.net, Shelton, Samuel J.¹ (AUTHOR) sam_shelton@hotmail.com, Brody, Daniel J.¹ (AUTHOR) daniel.brody@ucsf.edu, Eliscu, Rebecca¹ (AUTHOR) rebecca.eliscu@ucsf.edu, Johnson, Brett E.¹ (AUTHOR) johnbret@ohsu.edu, Mazor, Tali^1,2 (AUTHOR) tmazor@ds.dfci.harvard.edu, Kelley, Kevin W.^1,3,4 (AUTHOR) kwkelley@stanford.edu, Potts, Matthew B.¹ (AUTHOR) matthew.potts@nm.org, McDermott, Michael W.¹ (AUTHOR) mwmcd@baptisthealth.net, Huang, Eric J.⁵ (AUTHOR) eric.huang2@ucsf.edu, Lim, Daniel A.¹ (AUTHOR) daniel.lim@ucsf.edu, Pieper, Russell O.¹ (AUTHOR) russ.pieper@ucsf.edu, Berger, Mitchel S.¹ (AUTHOR) mitchel.berger@ucsf.edu, Costello, Joseph F.¹ (AUTHOR) joseph.costello@ucsf.edu, Phillips, Joanna J.^1,5 (AUTHOR) joanna.phillips@ucsf.edu, Oldham, Michael C.¹ (AUTHOR) michael.oldham@ucsf.edu

Publikováno v: Cancers. Jul2024, Vol. 16 Issue 13, p2429. 37p.

Blood RNA Profiles are Diagnostic for Severity in Human Acute Spinal Cord Injury

Autor: Kyritsis, Nikos, Espin, Abel Torres, Schupp, Patrick G., Huie, J. Russell, Chou, Austin, Duong-Fernandez, Xuan, Thomas, Leigh H., Tsolinas, Rachel E., Hemmerle, Debra D., Pascual, Lisa U., Singh, Vineeta, Pan, Jonathan Z., Talbott, Jason F., Whetstone, William D., Burke, John F., DiGiorgio, Anthony M., Weinstein, Philip R., Manley, Geoffrey T., Dhall, Sanjay S., Ferguson, Adam R., Oldham, Michael C., Bresnahan, Jacqueline C., Beattie, Michael S.

Biomarkers of spinal cord injury (SCI) could help determine the severity of the injury and facilitate early critical care decision making. We analyzed global gene expression in peripheral white blood cells during the acute injury phase and identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce038e4d5cf9cf0d026aac584875537c
https://doi.org/10.1101/2020.04.15.037325

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Quantitative assessment of timing, efficiency, specificity and genetic mosaicism of CRISPR/Cas9-mediated gene editing of hemoglobin beta gene in rhesus monkey embryos

Autor: Midic, Uros, Hung, Pei-Hsuan, Vincent, Kailey A, Goheen, Benjamin, Schupp, Patrick G, Chen, Diane D, Bauer, Daniel E, VandeVoort, Catherine A, Latham, Keith E

Publikováno v: Human molecular genetics, vol 26, iss 14

Gene editing technologies offer new options for developing novel biomedical research models and for gene and stem cell based therapies. However, applications in many species demand high efficiencies, specificity, and a thorough understanding of likel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::bc5473219ce8eb9419baef15fa891baa
https://escholarship.org/uc/item/8sh493x8