Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Schumitzky, Alan"'
Autor:
Chen, Rong, Schumitzky, Alan, Kryshchenko, Alona, Otalvaro, Julian D., Yamada, Walter M., Neely, Michael N.
In this paper we describe NPSA, the first parallel nonparametric global maximum likelihood optimization algorithm using simulated annealing (SA). Unlike the nonparametric adaptive grid search method NPAG, which is not guaranteed to find a global opti
Externí odkaz:
http://arxiv.org/abs/2301.12656
Autor:
Chen, Rong, Schumitzky, Alan, Kryshchenko, Alona, Garreau, Romain, Otalvaro, Julian D., Yamada, Walter M., Neely, Michael N.
Inspired from quantum Monte Carlo, by using unbiased estimators all the time and sampling discrete and continuous variables at the same time using Metropolis algorithm, we present a novel, fast, and accurate high performance Monte Carlo Parametric Ex
Externí odkaz:
http://arxiv.org/abs/2206.02077
Autor:
Chen, Rong1,2 (AUTHOR), Schumitzky, Alan2,3 (AUTHOR), Kryshchenko, Alona4 (AUTHOR), Nieforth, Keith1 (AUTHOR), Tomashevskiy, Michael1 (AUTHOR), Hu, Shuhua1 (AUTHOR), Garreau, Romain5,6 (AUTHOR), Otalvaro, Julian2 (AUTHOR), Yamada, Walter2 (AUTHOR), Neely, Michael N.2,7 (AUTHOR) rong.chen@certara.com
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. May2024, Vol. 13 Issue 5, p759-780. 22p.
In this paper we develop a nonparametric maximum likelihood estimate of the mixing distribution of the parameters of a linear stochastic dynamical system. This includes, for example, pharmacokinetic population models with process and measurement nois
Externí odkaz:
http://arxiv.org/abs/1509.04350
Autor:
Tatarinova, Tatiana, Neely, Michael, Bartroff, Jay, van Guilder, Michael, Yamada, Walter, Bayard, David, Jelliffe, Roger, Leary, Robert, Chubatiuk, Alyona, Schumitzky, Alan
Publikováno v:
Tatarinova et al, Journal of Pharmacokinetics and Pharmacodynamics, 2013, vol. 40 no 1
Population pharmacokinetic (PK) modeling methods can be statistically classified as either parametric or nonparametric (NP). Each classification can be divided into maximum likelihood (ML) or Bayesian (B) approaches. In this paper we discuss the nonp
Externí odkaz:
http://arxiv.org/abs/1303.6700
Autor:
Louie, Arnold, Liu, Weiguo, VanGuilder, Michael, Neely, Michael N., Schumitzky, Alan, Jelliffe, Roger, Fikes, Steven, Kurhanewicz, Stephanie, Robbins, Nichole, Brown, David, Baluya, Dodge, Drusano, George L
Publikováno v:
The Journal of Infectious Diseases, 2015 Apr . 211(8), 1326-1333.
Externí odkaz:
http://www.jstor.org/stable/43708356
Publikováno v:
In Computational Statistics and Data Analysis 2009 53(12):3907-3915
Publikováno v:
Biometrics, 1982 Dec 01. 38(4), 1089-1092.
Externí odkaz:
https://www.jstor.org/stable/2529891
Autor:
Schumitzky, Alan
Publikováno v:
Journal of the Society for Industrial and Applied Mathematics, 1965 Dec 01. 13(4), 1019-1032.
Externí odkaz:
https://www.jstor.org/stable/2946421
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