Zobrazeno 1 - 10
of 3 803
pro vyhledávání: '"Schroeder, Michael"'
The response of cells to their environment is driven by a variety of proteins and messenger molecules. In eukaryotes, their distribution and location in the cell are regulated by the vesicular transport system. The transport of aquaporin 2 between me
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A91156
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https://tud.qucosa.de/api/qucosa%3A91156/attachment/ATT-0/
Antibiotic resistance is a global health threat and consequently, there is a need to understand the mechanisms driving its emergence. Here, we hypothesize that genes and mutations under positive selection may contribute to antibiotic resistance. We e
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A91271
https://tud.qucosa.de/api/qucosa%3A91271/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A91271/attachment/ATT-0/
Gene expression can serve as a powerful predictor for disease progression and other phenotypes. Consequently, microarrays, which capture gene expression genome-wide, have been used widely over the past two decades to derive biomarker signatures for t
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A90143
https://tud.qucosa.de/api/qucosa%3A90143/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A90143/attachment/ATT-0/
Background: Structure-based drug repositioning has emerged as a promising alternative to conventional drug development. Regardless of the many success stories reported over the past years and the novel breakthroughs on the AI-based system AlphaFold f
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A88527
https://tud.qucosa.de/api/qucosa%3A88527/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A88527/attachment/ATT-0/
Autor:
Acevedo, Aldo, Duran, Claudio, Kuo, Ming-Ju, Ciucci, Sara, Schroeder, Michael, Cannistraci, Carlo Vittorio
Evaluating group separability is fundamental to pattern recognition. A plethora of dimension reduction (DR) algorithms has been developed to reveal the emergence of geometrical patterns in a lowdimensional space, where high-dimensional sample similar
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A88284
https://tud.qucosa.de/api/qucosa%3A88284/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A88284/attachment/ATT-0/
Publikováno v:
PLoS Computational Biology (2017), 13(12). S. 1-11. ISSN: 1553-7358 . DOI: 10.1371/journal.pcbi.1005898.
Over the past decades, quantitative methods linking theory and observation became increasingly important in many areas of life science. Subsequently, a large number of mathematical and computational models has been developed. The BioModels database a
Autor:
Mahfouz, Norhan, Caucci, Serena, Achatz, Eric, Semmler, Torsten, Guenther, Sebastian, Berendonk, Thomas U., Schroeder, Michael
Wastewater treatment plants play an important role in the emergence of antibiotic resistance. They provide a hot spot for exchange of resistance within and between species. Here, we analyse and quantify the genomic diversity of the indicator Escheric
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A32482
https://tud.qucosa.de/api/qucosa%3A32482/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A32482/attachment/ATT-0/
Autor:
Salentin, Sebastian, Adasme, Melissa F., Heinrich, Jörg C., Haupt, V. Joachim, Daminelli, Simone, Zhang, Yixin, Schroeder, Michael
Publikováno v:
Scientific Reports (2017). 7
Drug repositioning identifies new indications for known drugs. Here we report repositioning of the malaria drug amodiaquine as a potential anti-cancer agent. While most repositioning efforts emerge through serendipity, we have devised a computational
Background: Ad hoc parsers are pieces of code that use common string functions like split, trim, or slice to effectively perform parsing. Whether it is handling command-line arguments, reading configuration files, parsing custom file formats, or any
Externí odkaz:
http://arxiv.org/abs/2304.09733