Cisplatin coordination chemistry determination at hen egg white lysozyme His15 with ligand distances and angles, and their standard uncertainties, and also reporting a split occupancy effect

Autor: Helliwell, John R., Tanley, Simon W. M., Schreurs, Antoine M. M., Kroon-Batenburg, Loes M. J.

Following the interest of L Messori and A Merlino 2016 Coordination Chemistry Reviews in the platinum ions coordination geometries in our PDB entries 4dd4 and 4dd6 we have extended our original analyses.
Comment: 10 pages. One figure with two st

Externí odkaz: http://arxiv.org/abs/1606.01372

Carboplatin binding to a model protein in non-NaCl conditions to eliminate partial conversion to cisplatin, and the use of different criteria to choose the resolution limit

Autor: Tanley, Simon W. M, Diederichs, Kay, Kroon-Batenburg, Loes M. J, Schreurs, Antoine M. M, Helliwell, John R

Hen egg white lysozyme (HEWL) co-crystallisation conditions of carboplatin without sodium chloride (NaCl) have been utilised to eliminate partial conversion of carboplatin to cisplatin observed previously. Tetragonal HEWL crystals were successfully o

Externí odkaz: http://arxiv.org/abs/1309.4661

Re-refinement of 4xan: hen egg-white lysozyme with carboplatin in sodium bromide solution

Autor: Tanley, Simon W. M., Schreurs, Antoine M. M., Kroon - Batenburg, Louise, Helliwell, John R.

A re-refinement of 4xan, hen egg white lysozyme (HEWL) with carboplatin crystallised in NaBr solution, has been made (Tanley et al 2016). This follows our Response article (Tanley et al 2015) to the Critique article of Shabalin et al 2015, suggesting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::c9f21d14870391f1144e2f1ce55cc0f3
https://dspace.library.uu.nl/handle/1874/343736

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Carboplatin binding to histidine

Autor: Tanley, Simon W M, Diederichs, Kay, Kroon - Batenburg, Louise, Levy, Colin, Schreurs, Antoine M M, Helliwell, John R., Crystal and Structural Chemistry, Sub Crystal and Structural Chemistry, Bijvoet Centre for Biomolecular Research

Publikováno v: Tanley, S W, Diederichs, K, Kroon-Batenburg, L M, Levy, C, Schreurs, A M & Helliwell, J R 2014, ' Carboplatin binding to histidine ', Acta Crystallographica Section F: Structural Biology and Crystallization Communications, vol. 70, no. 9, pp. 1135-1142 . https://doi.org/10.1107/S2053230X14016161, https://doi.org/10.1107/S2053230X14016161, https://doi.org/10.1107/S2053230X14016161
Acta crystallographica. Section F, Structural biology and crystallization communications, 70(9), 1135. Wiley-Blackwell
Acta Crystallographica. Section F, Structural Biology Communications

An X-ray crystal structure showing the binding of purely carboplatin to histidine in a model protein has finally been obtained. This required extensive crystallization trials and various novel crystal structure analyses.
Carboplatin is a second-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242c4d32a6e2188531d71b8155236e45
https://www.ncbi.nlm.nih.gov/pubmed/25195881