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Identification of isoAsp7-Aβ as a major Aβ variant in Alzheimer's disease, dementia with Lewy bodies and vascular dementia.

Autor: Schrempel S; Paul Flechsig Institute - Centre of Neuropathology and Brain Research, University of Leipzig, Liebigstraße 19, 04103, Leipzig, Germany., Kottwitz AK; Department of Molecular Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, 06120, Halle (Saale), Germany.; Center for Natural Product-based Therapeutics, Anhalt University of Applied Sciences, 06366, Köthen, Germany., Piechotta A; Department of Molecular Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, 06120, Halle (Saale), Germany., Gnoth K; Department of Molecular Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, 06120, Halle (Saale), Germany.; Center for Natural Product-based Therapeutics, Anhalt University of Applied Sciences, 06366, Köthen, Germany., Büschgens L; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Georg-August-University, 37075, Göttingen, Germany., Hartlage-Rübsamen M; Paul Flechsig Institute - Centre of Neuropathology and Brain Research, University of Leipzig, Liebigstraße 19, 04103, Leipzig, Germany., Morawski M; Paul Flechsig Institute - Centre of Neuropathology and Brain Research, University of Leipzig, Liebigstraße 19, 04103, Leipzig, Germany., Schenk M; Department of Molecular Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, 06120, Halle (Saale), Germany., Kleinschmidt M; Department of Molecular Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, 06120, Halle (Saale), Germany., Serrano GE; Civin Laboratory for Neuropathology, Brain and Body Donation Program, Banner Sun Health Research Institute, 10515 W Santa Fe Drive, Sun City, AZ, 85351, USA., Beach TG; Civin Laboratory for Neuropathology, Brain and Body Donation Program, Banner Sun Health Research Institute, 10515 W Santa Fe Drive, Sun City, AZ, 85351, USA., Rostagno A; Department of Pathology, New York University School of Medicine, New York, NY, USA., Ghiso J; Department of Pathology, New York University School of Medicine, New York, NY, USA., Heneka MT; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belval, Luxembourg., Walter J; Center of Neurology, Molecular Cell Biology, University Hospital Bonn, 53127, Bonn, Germany., Wirths O; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Georg-August-University, 37075, Göttingen, Germany., Schilling S; Department of Molecular Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, 06120, Halle (Saale), Germany.; Center for Natural Product-based Therapeutics, Anhalt University of Applied Sciences, 06366, Köthen, Germany., Roßner S; Paul Flechsig Institute - Centre of Neuropathology and Brain Research, University of Leipzig, Liebigstraße 19, 04103, Leipzig, Germany. steffen.rossner@medizin.uni-leipzig.de.

Publikováno v: Acta neuropathologica [Acta Neuropathol] 2024 Dec 03; Vol. 148 (1), pp. 78. Date of Electronic Publication: 2024 Dec 03.