Investigation of AML-specific FLT3 mutations – from next generation diagnostics to combined targeted therapy

Autor: Schranz, Katrin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b73f1b5184d7a2ae179361dbb48f8fb1

Clonal heterogeneity of FLT3 -ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia.

Autor: Schranz K; Experimental Leukemia and Lymphoma Research, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Consortium, partner site Munich, Germany.; German Cancer Research Center, Heidelberg, Germany., Hubmann M; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany., Harin E; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany., Vosberg S; Experimental Leukemia and Lymphoma Research, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Consortium, partner site Munich, Germany.; German Cancer Research Center, Heidelberg, Germany., Herold T; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Consortium, partner site Munich, Germany.; German Cancer Research Center, Heidelberg, Germany., Metzeler KH; Experimental Leukemia and Lymphoma Research, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Consortium, partner site Munich, Germany.; German Cancer Research Center, Heidelberg, Germany., Rothenberg-Thurley M; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Consortium, partner site Munich, Germany.; German Cancer Research Center, Heidelberg, Germany., Janke H; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany., Bräundl K; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Consortium, partner site Munich, Germany.; German Cancer Research Center, Heidelberg, Germany., Ksienzyk B; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany., Batcha AMN; Department of Medical Data Processing, Biometrie and Epidemiology, LMU Munich, Munich, Germany., Schaaf S; Department of Medical Data Processing, Biometrie and Epidemiology, LMU Munich, Munich, Germany., Schneider S; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; Institute of Human Genetics, University Hospital, LMU Munich, Munich, Germany., Bohlander SK; Leukaemia and Blood Cancer Research Unit, Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand., Görlich D; Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany., Berdel WE; Department of Medicine A, Hematology and Oncology, University of Münster, Münster, Germany., Wörmann BJ; Division of Hematology and Oncology, Charité Universitätsmedizin Berlin, Campus Virchow, Berlin, Germany., Braess J; Department of Hematology and Oncology, Barmherzige Brüder Hospital, Regensburg, Germany., Krebs S; Laboratory for Functional Genome Analysis, Gene Center, LMU Munich, Munich, Germany., Hiddemann W; Experimental Leukemia and Lymphoma Research, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Consortium, partner site Munich, Germany.; German Cancer Research Center, Heidelberg, Germany., Mansmann U; Department of Medical Data Processing, Biometrie and Epidemiology, LMU Munich, Munich, Germany., Spiekermann K; Experimental Leukemia and Lymphoma Research, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Consortium, partner site Munich, Germany.; German Cancer Research Center, Heidelberg, Germany., Greif PA; Experimental Leukemia and Lymphoma Research, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; German Cancer Consortium, partner site Munich, Germany.; German Cancer Research Center, Heidelberg, Germany.

Publikováno v: Oncotarget [Oncotarget] 2018 Jul 10; Vol. 9 (53), pp. 30128-30145. Date of Electronic Publication: 2018 Jul 10 (Print Publication: 2018).