Ancient human genomes suggest three ancestral populations for present-day Europeans

Autor: Mahley, Robert, Lazaridis, I, Patterson, N, Mittnik, A, Renaud, G, Mallick, S, Kirsanow, K, Sudmant, PH, Schraiber, JG, Castellano, S, Lipson, M

Publikováno v: Mahley, Robert; Lazaridis, I; Patterson, N; Mittnik, A; Renaud, G; Mallick, S; et al.(2014). Ancient human genomes suggest three ancestral populations for present-day Europeans. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7pn797tm

©2014 Macmillan Publishers Limited. All rights reserved.We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes1-4 with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::cab8fae7ac5bee97d16197a122ba3b66
http://www.escholarship.org/uc/item/7pn797tm

A path integral approach for allele frequency dynamics under polygenic selection.

Autor: Anderson NW; Department of Integrative Biology, University of Wisconsin-Madison, Madison, WI, 53706, USA., Kirk L; Department of Integrative Biology, University of Wisconsin-Madison, Madison, WI, 53706, USA., Schraiber JG; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA, 90089, USA., Ragsdale AP; Department of Integrative Biology, University of Wisconsin-Madison, Madison, WI, 53706, USA.

Publikováno v: Genetics [Genetics] 2024 Nov 12. Date of Electronic Publication: 2024 Nov 12.

Estimation of demography and mutation rates from one million haploid genomes.

Autor: Schraiber JG, Spence JP, Edge MD

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 21. Date of Electronic Publication: 2024 Sep 21.

Heritability within groups is uninformative about differences among groups: Cases from behavioral, evolutionary, and statistical genetics.

Autor: Schraiber JG; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA 90089-2911., Edge MD; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA 90089-2911.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Mar 19; Vol. 121 (12), pp. e2319496121. Date of Electronic Publication: 2024 Mar 12.

Identification of constrained sequence elements across 239 primate genomes.

Autor: Kuderna LFK; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Ulirsch JC; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Rashid S; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Ameen M; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Sundaram L; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Hickey G; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA., Cox AJ; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Gao H; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Kumar A; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Aguet F; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., Christmas MJ; Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden., Clawson H; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA., Haeussler M; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA., Janiak MC; School of Science, Engineering and Environment, University of Salford, Salford, UK., Kuhlwilm M; Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.; Human Evolution and Archaeological Sciences (HEAS), University of Vienna, Vienna, Austria., Orkin JD; Département d'Anthropologie, Université de Montréal, Montréal, Quebec, Canada., Bataillon T; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Manu S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India., Valenzuela A; IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain., Bergman J; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.; Section for Ecoinformatics and Biodiversity, Department of Biology, Aarhus University, Aarhus, Denmark., Rouselle M; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Silva FE; Research Group on Primate Biology and Conservation, Mamirauá Institute for Sustainable Development, Tefé, Brazil.; Evolutionary Biology and Ecology (EBE), Département de Biologie des Organismes, Université libre de Bruxelles (ULB), Brussels, Belgium., Agueda L; Centro Nacional de Analisis Genomico (CNAG), Barcelona, Spain., Blanc J; Centro Nacional de Analisis Genomico (CNAG), Barcelona, Spain., Gut M; Centro Nacional de Analisis Genomico (CNAG), Barcelona, Spain., de Vries D; School of Science, Engineering and Environment, University of Salford, Salford, UK., Goodhead I; School of Science, Engineering and Environment, University of Salford, Salford, UK., Harris RA; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Raveendran M; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Jensen A; Department of Ecology and Genetics, Animal Ecology, Uppsala University, Uppsala, Sweden., Chuma IS; Tanzania National Parks, Arusha, Tanzania., Horvath JE; North Carolina Museum of Natural Sciences, Raleigh, NC, USA.; Department of Biological and Biomedical Sciences, North Carolina Central University, Durham, NC, USA.; Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA.; Department of Evolutionary Anthropology, Duke University, Durham, NC, USA.; Renaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Hvilsom C; Copenhagen Zoo, Frederiksberg, Denmark., Juan D; IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain., Frandsen P; Copenhagen Zoo, Frederiksberg, Denmark., Schraiber JG; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA., de Melo FR; Universidade Federal de Viçosa, Viçosa, Brazil., Bertuol F; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL), Manaus, Brazil., Byrne H; Department of Anthropology, University of Utah, Salt Lake City, UT, USA., Sampaio I; Universidade Federal do Para, Bragança, Brazil., Farias I; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL), Manaus, Brazil., Valsecchi J; Research Group on Terrestrial Vertebrate Ecology, Mamirauá Institute for Sustainable Development, Tefé, Brazil.; Rede de Pesquisa em Diversidade, Conservação e Uso da Fauna da Amazônia - RedeFauna, Manaus, Brazil.; Comunidad de Manejo de Fauna Silvestre en la Amazonía y en Latinoamérica-ComFauna, Iquitos, Peru., Messias M; Universidade Federal de Rondônia, Porto Velho, Brazil., da Silva MNF; Instituto Nacional de Pesquisas da Amazônia, Manaus, Brazil., Trivedi M; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India., Rossi R; Instituto de Biociências, Universidade Federal do Mato Grosso, Cuiabá, Brazil., Hrbek T; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL), Manaus, Brazil.; Department of Biology, Trinity University, San Antonio, TX, USA., Andriaholinirina N; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, Madagascar., Rabarivola CJ; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, Madagascar., Zaramody A; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, Madagascar., Jolly CJ; Department of Anthropology, New York University, New York, NY, USA., Phillips-Conroy J; Department of Neuroscience, Washington University School of Medicine in St Louis, St Louis, MO, USA., Wilkerson G; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Bastrop, TX, USA., Abee C; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Bastrop, TX, USA., Simmons JH; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Bastrop, TX, USA., Fernandez-Duque E; Department of Anthropology, Yale University, New Haven, CT, USA., Kanthaswamy S; School of Interdisciplinary Forensics, Arizona State University, Phoenix, AZ, USA.; California National Primate Research Center, University of California, Davis, CA, USA., Shiferaw F; Guinea Worm Eradication Program, The Carter Center Ethiopia, Addis Ababa, Ethiopia., Wu D; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China., Zhou L; Center for Evolutionary and Organismal Biology, Zhejiang University School of Medicine, Hangzhou, China., Shao Y; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China., Zhang G; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.; Center for Evolutionary and Organismal Biology, Zhejiang University School of Medicine, Hangzhou, China.; Villum Centre for Biodiversity Genomics, Section for Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen, Denmark.; Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, China.; Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Keyyu JD; Tanzania Wildlife Research Institute (TAWIRI), Arusha, Tanzania., Knauf S; Institute of International Animal Health/One Health, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.; Professorship for International Animal Health/One Health, Faculty of Veterinary Medicine, Justus Liebig University, Giessen, Germany., Le MD; Department of Environmental Ecology, Faculty of Environmental Sciences, University of Science and Central Institute for Natural Resources and Environmental Studies, Vietnam National University, Hanoi, Vietnam., Lizano E; IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.; Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona, Barcelona, Spain., Merker S; Department of Zoology, State Museum of Natural History Stuttgart, Stuttgart, Germany., Navarro A; IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain., Nadler T; Cuc Phuong Commune, Nho Quan District, Vietnam., Khor CC; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Lee J; Mandai Nature, Singapore, Singapore., Tan P; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.; SingHealth Duke-NUS Institute of Precision Medicine (PRISM), Singapore, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Lim WK; SingHealth Duke-NUS Institute of Precision Medicine (PRISM), Singapore, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; SingHealth Duke-NUS Genomic Medicine Centre, Singapore, Singapore., Kitchener AC; Department of Natural Sciences, National Museums Scotland, Edinburgh, UK.; School of Geosciences, Edinburgh, UK., Zinner D; Cognitive Ethology Laboratory, Germany Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.; Department of Primate Cognition, Georg-August-Universität Göttingen, Göttingen, Germany.; Leibniz ScienceCampus Primate Cognition, Göttingen, Germany., Gut I; Centro Nacional de Analisis Genomico (CNAG), Barcelona, Spain., Melin AD; Department of Anthropology and Archaeology, University of Calgary, Calgary, Alberta, Canada.; Department of Medical Genetics, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada., Guschanski K; Department of Ecology and Genetics, Animal Ecology, Uppsala University, Uppsala, Sweden.; Institute of Ecology and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, UK., Schierup MH; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Beck RMD; School of Science, Engineering and Environment, University of Salford, Salford, UK., Karakikes I; Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA., Wang KC; Department of Cancer Biology, Stanford University, Stanford, CA, USA.; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA.; Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA, USA., Umapathy G; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India., Roos C; Gene Bank of Primates and Primate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany., Boubli JP; School of Science, Engineering and Environment, University of Salford, Salford, UK., Siepel A; Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Kundaje A; Department of Computer Science, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University, Stanford, CA, USA., Paten B; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA., Lindblad-Toh K; Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Rogers J; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. jr13@bcm.edu., Marques Bonet T; IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain. tomas.marques@upf.edu.; Centro Nacional de Analisis Genomico (CNAG), Barcelona, Spain. tomas.marques@upf.edu.; Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona, Barcelona, Spain. tomas.marques@upf.edu.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain. tomas.marques@upf.edu.; Universitat Pompeu Fabra, Barcelona, Spain. tomas.marques@upf.edu., Farh KK; Illumina Artificial Intelligence Laboratory, Illumina, San Diego, CA, USA. kfarh@illumina.com.

Publikováno v: Nature [Nature] 2024 Jan; Vol. 625 (7996), pp. 735-742. Date of Electronic Publication: 2023 Nov 29.