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Targeting Gα i2 in neutrophils protects from myocardial ischemia reperfusion injury.

Autor: Köhler D; Department of Anesthesiology and Intensive Care Medicine, Eberhard Karls University, Tübingen, Germany., Leiss V; Department of Pharmacology, Experimental Therapy and Toxicology, Institute for Experimental and Clinical Pharmacology and Pharmacogenomic, Eberhard Karls University, and Interfaculty Center of Pharmacogenomic and Drug Research, Wilhelmstrasse 56, 72074, Tübingen, Germany., Beichert L; Department of Pharmacology, Experimental Therapy and Toxicology, Institute for Experimental and Clinical Pharmacology and Pharmacogenomic, Eberhard Karls University, and Interfaculty Center of Pharmacogenomic and Drug Research, Wilhelmstrasse 56, 72074, Tübingen, Germany., Killinger S; Department of Pharmacology, Experimental Therapy and Toxicology, Institute for Experimental and Clinical Pharmacology and Pharmacogenomic, Eberhard Karls University, and Interfaculty Center of Pharmacogenomic and Drug Research, Wilhelmstrasse 56, 72074, Tübingen, Germany., Grothe D; Department of Pharmacology, Experimental Therapy and Toxicology, Institute for Experimental and Clinical Pharmacology and Pharmacogenomic, Eberhard Karls University, and Interfaculty Center of Pharmacogenomic and Drug Research, Wilhelmstrasse 56, 72074, Tübingen, Germany., Kushwaha R; Department of Pharmacology, Experimental Therapy and Toxicology, Institute for Experimental and Clinical Pharmacology and Pharmacogenomic, Eberhard Karls University, and Interfaculty Center of Pharmacogenomic and Drug Research, Wilhelmstrasse 56, 72074, Tübingen, Germany., Schröter A; Department of Pharmacology, Experimental Therapy and Toxicology, Institute for Experimental and Clinical Pharmacology and Pharmacogenomic, Eberhard Karls University, and Interfaculty Center of Pharmacogenomic and Drug Research, Wilhelmstrasse 56, 72074, Tübingen, Germany., Roslan A; Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany., Eggstein C; Department of Anesthesiology and Intensive Care Medicine, Eberhard Karls University, Tübingen, Germany., Focken J; Division of Dermatooncology, Department of Dermatology, Eberhard Karls University, Tübingen, Germany., Granja T; Department of Anesthesiology and Intensive Care Medicine, Eberhard Karls University, Tübingen, Germany., Devanathan V; Department of Pharmacology, Experimental Therapy and Toxicology, Institute for Experimental and Clinical Pharmacology and Pharmacogenomic, Eberhard Karls University, and Interfaculty Center of Pharmacogenomic and Drug Research, Wilhelmstrasse 56, 72074, Tübingen, Germany.; Department of Biology, Indian Institute of Science Education and Research (IISER) Tirupati, Tirupati, 517507, India., Schittek B; Division of Dermatooncology, Department of Dermatology, Eberhard Karls University, Tübingen, Germany., Lukowski R; Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany., Weigelin B; Department of Preclinical Imaging and Radiopharmacy, Multiscale Immunoimaging, Eberhard Karls University, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University, Tübingen, Germany., Rosenberger P; Department of Anesthesiology and Intensive Care Medicine, Eberhard Karls University, Tübingen, Germany., Nürnberg B; Department of Pharmacology, Experimental Therapy and Toxicology, Institute for Experimental and Clinical Pharmacology and Pharmacogenomic, Eberhard Karls University, and Interfaculty Center of Pharmacogenomic and Drug Research, Wilhelmstrasse 56, 72074, Tübingen, Germany., Beer-Hammer S; Department of Pharmacology, Experimental Therapy and Toxicology, Institute for Experimental and Clinical Pharmacology and Pharmacogenomic, Eberhard Karls University, and Interfaculty Center of Pharmacogenomic and Drug Research, Wilhelmstrasse 56, 72074, Tübingen, Germany. sandra.beer-hammer@uni-tuebingen.de.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University, Tübingen, Germany. sandra.beer-hammer@uni-tuebingen.de.

Publikováno v: Basic research in cardiology [Basic Res Cardiol] 2024 Oct; Vol. 119 (5), pp. 717-732. Date of Electronic Publication: 2024 May 30.