Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Schottmann R"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Schottmann R, Alfons Lampen, A Linck, Augustinus Bader, Uwe Christians, Karl-Friedrich Sewing, Gudrun Schmidt
Publikováno v:
British Journal of Clinical Pharmacology. 41:187-190
1. Tacrolimus, an immunosuppressive macrolide, is metabolized by enzymes of the cytochrome P450 3A subfamily. In this study, 34 drugs were tested for their interactions with tacrolimus metabolism by human liver microsomes. 2. Fifteen drugs which inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c610e73a0cbd1fac026f858bfb894dd9
https://doi.org/10.1111/j.1365-2125.1996.tb00181.x
https://doi.org/10.1111/j.1365-2125.1996.tb00181.x
Autor:
Thomas Sürig, Burckhardt Ringe, Karl-Friedrich Sewing, Augustinus Bader, Kay Kohlhaw, A Linck, Schottmann R, Uwe Christians
Publikováno v:
Therapeutic Drug Monitoring. 17:487-498
Cyclosporine, a cyclic undecapeptide, is currently the major immunosuppressant used after liver transplantation. Since it is unclear whether or not cyclosporine metabolites play a part in toxicity, high concentrations of metabolites should be avoided
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deaf157bc8da9b48fb63a68e627cf936
https://doi.org/10.1097/00007691-199510000-00009
https://doi.org/10.1097/00007691-199510000-00009
Autor:
R. Kownatzki, Heinfried H. Radeke, Uwe Christians, Hans-Martin Schiebel, Schottmann R, Karl-Fr. Sewing
Publikováno v:
Clinical Biochemistry. 24:271-275
Metabolism of FK506, a 23 member macrolide under clinical investigation as immunosuppressant after transplantation, was studied using human liver microsomes. Two fractions isolated by semipreparative HPLC were identified by negative fast atom bombard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851c606c1cdc7f0883a8557acd5e54ea
https://doi.org/10.1016/0009-9120(91)80019-y
https://doi.org/10.1016/0009-9120(91)80019-y
Autor:
Uwe Christians, R. Kownatzki, S. Strohmeyer, Hans-Martin Schiebel, Schottmann R, K F Sewing, Jörg S. Bleck, K. Kohlhaw
Publikováno v:
Xenobiotica. 21:1199-1210
1. Cyclosporine and its metabolites, isolated from human bile and identified by FAB mass spectrometry and 1H-n.m.r. spectroscopy, were metabolized by human liver microsomes for the identification of new cyclosporine metabolites. From these data a met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316e6c17e9a49ac5a647c1c803b62c1e
https://doi.org/10.3109/00498259109039560
https://doi.org/10.3109/00498259109039560
Autor:
Charles Cano, F., Kloos, A., Fangmann, T., Kattre, N., Schottmann, R., Döhner, K., Ganser, A., Heuser, M.
Publikováno v:
HemaSphere; 2022 Supplement 3, Vol. 6, p294-295, 2p
Autor:
K. Kohlhaw, Schottmann R, K F Sewing, J Greipel, Jörg S. Bleck, S. Strohmeyer, Uwe Christians, Hans-Martin Schiebel, R. Kownatzki
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 21(9)
1. Cyclosporine metabolites of known and unknown structures were isolated, by semi-preparative h.p.l.c., from human bile from the T-tube of liver-grafted patients, who received cyclosporine treatment. Their structures were elucidated by FAB mass spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2154907a5bc9d0486e6f95941dbb94c
https://pubmed.ncbi.nlm.nih.gov/1788987
https://pubmed.ncbi.nlm.nih.gov/1788987
Autor:
Christians, U., Kohlhaw, K., Budniak, J., Bleck, J. S., Schottmann, R., Schlitt, Hans-Jürgen, Almeida, V. M., Deters, M., Wonigeit, K., Pichlmayr, R.
Blood ciclosporin (Cs) metabolite pattern in 58 liver grafted patients was routinely monitored by HPLC from the first Cs dose after transplantation until discharge from hospital. Eighteen patients with normal kidney function were allocated to Group I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f87867c51b2f4f631b339bf9e651d44d
Autor:
Christians, U., Kohlhaw, K., Budniak, J., Bleck, J. S., Schottmann, R., Schlitt, Hans-Jürgen, Almeida, V. M., Deters, M., Wonigeit, K., Pichlmayr, R.
The pattern of metabolites of ciclosporin in blood and 24 h-urine of 58 liver graft recipients was routinely monitored by HPLC from transplantation until discharge from hospital. Liver function and ciclosporin metabolite pattern in patients with an u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0826dc42c85d66f71cbbaa4069398b8d
Autor:
Kf, Sewing, Christians U, Kohlhaw K, Heinfried Radeke, Strohmeyer S, Kownatzki R, Budniak J, Schottmann R, Js, Bleck, Vm, Almeida
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d13bdef8d4f674b13e8221ef664b1009
https://pubmed.ncbi.nlm.nih.gov/2349673
https://pubmed.ncbi.nlm.nih.gov/2349673