Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Schornagel, J."'
Autor:
Rasch, C.R.N., Hauptmann, M., Schornagel, J., Wijers, O., Buter, J., Gregor, T., Wiggenraad, R., Boer, J.P. de, Ackerstaff, A.H., Kroger, R., Hoebers, F.J.P., Balm, A.J.M., Hilgers, F.J.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::067f44b005bfc1d0b44d11ba4c0f7549
https://doi.org/10.1002/cncr.25234
https://doi.org/10.1002/cncr.25234
Publikováno v:
Nederlands tijdschrift voor geneeskunde, 149(2), 61-64. Bohn Stafleu van Loghum
In The Netherlands each year there are 2300 new patients with a squamous-cell carcinoma of the larynx, pharynx and oral cavity, and of these, one-third has a locally regionally advanced tumour. An operation can then lead to an unacceptable loss of fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::8f731ebf0aaba5a2ac45b06e37d02ca5
https://pure.amc.nl/en/publications/de-rol-van-gelijktijdige-chemotherapie-en-radiotherapie-bij-de-behandeling-van-lokaal-uitgebreide-tumoren-van-larynx-farynx-en-mondholte(2e933089-c243-4897-b9ca-d43bbade108a).html
https://pure.amc.nl/en/publications/de-rol-van-gelijktijdige-chemotherapie-en-radiotherapie-bij-de-behandeling-van-lokaal-uitgebreide-tumoren-van-larynx-farynx-en-mondholte(2e933089-c243-4897-b9ca-d43bbade108a).html
Publikováno v:
Anticancer research, 23(3C), 2795-2800. International Institute of Anticancer Research
We evaluated the toxicity and efficacy of the first palliative chemotherapy regimen after failure of high-dose chemotherapy in 148 patients with primary or metastatic breast cancer treated with high-dose chemotherapy (one full dose CTC, (cyclophospha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::de74472d9ecc52be180df4066cded63f
https://pure.amc.nl/en/publications/palliative-chemotherapy-after-failure-of-highdose-chemotherapy-in-breast-cancertoxicity-and-efficacy(24e74cec-f18a-4c24-a707-7b05cc9d5c44).html
https://pure.amc.nl/en/publications/palliative-chemotherapy-after-failure-of-highdose-chemotherapy-in-breast-cancertoxicity-and-efficacy(24e74cec-f18a-4c24-a707-7b05cc9d5c44).html
Autor:
de Gast, G. C., Klümpen, H. J., Vyth-Dreese, F. A., Kersten, M. J., Verra, N. C., Sein, J., Batchelor, D., Nooijen, W. J., Schornagel, J. H.
Publikováno v:
Clinical cancer research, 6(4), 1267-1272. American Association for Cancer Research Inc.
The purpose of our study was to determine the maximally tolerated dose (MTD) and DLT of combined administration of granulocyte macrophage colony-stimulating factor (GM-CSF), low-dose interleukin 2 (IL-2) and IFN-alpha in patients with progressive met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::bdc6dd187d1d43fe1cf09151155942e8
https://pure.amc.nl/en/publications/phase-i-trial-of-combined-immunotherapy-with-subcutaneous-granulocyte-macrophage-colonystimulating-factor-lowdose-interleukin-2-and-interferon-alpha-in-progressive-metastatic-melanoma-and-renal-cell-carcinoma(05c303f9-9751-4e5f-b11c-60eecafd4d40).html
https://pure.amc.nl/en/publications/phase-i-trial-of-combined-immunotherapy-with-subcutaneous-granulocyte-macrophage-colonystimulating-factor-lowdose-interleukin-2-and-interferon-alpha-in-progressive-metastatic-melanoma-and-renal-cell-carcinoma(05c303f9-9751-4e5f-b11c-60eecafd4d40).html
Autor:
Jansen, G, Mauritz, R, Drori, S, Sprecher, H, Kathmann, I, Bunni, M, Priest, D G, Noordhuis, P, Schornagel, J H, Pinedo, H M, Peters, G J, Assaraf, Y G
Publikováno v:
Journal of Biological Chemistry, 273(46), 30189-98. American Society for Biochemistry and Molecular Biology Inc.
Jansen, G, Mauritz, R, Drori, S, Sprecher, H, Kathmann, I, Bunni, M, Priest, D G, Noordhuis, P, Schornagel, J H, Pinedo, H M, Peters, G J & Assaraf, Y G 1998, ' A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance ', Journal of Biological Chemistry, vol. 273, no. 46, pp. 30189-98 .
Jansen, G, Mauritz, R, Drori, S, Sprecher, H, Kathmann, I, Bunni, M, Priest, D G, Noordhuis, P, Schornagel, J H, Pinedo, H M, Peters, G J & Assaraf, Y G 1998, ' A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance ', Journal of Biological Chemistry, vol. 273, no. 46, pp. 30189-98 .
CEM/MTX is a subline of human CCRF-CEM leukemia cells which displays >200-fold resistance to methotrexate (MTX) due to defective transport via the reduced folate carrier (RFC). CEM/MTX-low folate (LF) cells, derived by a gradual deprivation of folic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b9703a0f735cae1c52a4609699aacbf8
https://research.vumc.nl/en/publications/1b93bc74-7514-4b86-b0dc-1a263e046acc
https://research.vumc.nl/en/publications/1b93bc74-7514-4b86-b0dc-1a263e046acc
Autor:
Sneeuw, K. C., Aaronson, N. K., Sprangers, M. A., Detmar, S. B., Wever, L. D., Schornagel, J. H.
Publikováno v:
Journal of clinical oncology, 15(3), 1206-1217. American Society of Clinical Oncology
PURPOSE: To evaluate the usefulness of caregiver ratings of cancer patients' quality of life (QL), we examined the following: (1) the comparability of responses to a brief standardized QL questionnaire provided by patients, physicians, and informal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::1fe362ace955d8a2e544311246a913eb
https://pure.amc.nl/en/publications/value-of-caregiver-ratings-in-evaluating-the-quality-of-life-of-patients-with-cancer(4ebbd206-4d96-4cf9-be76-d45d0a2789d9).html
https://pure.amc.nl/en/publications/value-of-caregiver-ratings-in-evaluating-the-quality-of-life-of-patients-with-cancer(4ebbd206-4d96-4cf9-be76-d45d0a2789d9).html
Publikováno v:
Journal of Cell Biology, 132(1-2), 35-47. Rockefeller University Press
Rijnboutt, S, Jansen, G, Posthuma, G, Hynes, J B, Schornagel, J H & Strous, G J 1996, ' Endocytosis of GPI-linked membrane folate receptor-alpha ', Journal of Cell Biology, vol. 132, no. 1-2, pp. 35-47 .
Rijnboutt, S, Jansen, G, Posthuma, G, Hynes, J B, Schornagel, J H & Strous, G J 1996, ' Endocytosis of GPI-linked membrane folate receptor-alpha ', Journal of Cell Biology, vol. 132, no. 1-2, pp. 35-47 .
GPI-linked membrane folate receptors (MFRs) have been implicated in the receptor-mediated uptake of reduced folate cofactors and folate-based chemotherapeutic drugs. We have studied the biosynthetic transport to and internalization of MFR isoform alp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::881196fbb309be4f9c036c8fd4395732
https://research.vumc.nl/en/publications/879a656e-0639-4fd5-ab4d-b78f89272899
https://research.vumc.nl/en/publications/879a656e-0639-4fd5-ab4d-b78f89272899
Autor:
Baars, J. W., Holtkamp, M. J., Nooyen, W. J., Walll, E. V., te Velde, A., Dalesio, O., Slaper-Cortenbach, I. C., Schoot, E. V., Richel, D. J., Gerritsen, W. R., Schornagel, J. H., Rodenhuis, S.
Publikováno v:
Anticancer research, 16(5B), 3089-3095. International Institute of Anticancer Research
The mobilisation characteristics of ifosfamide and etoposide followed by Granulocyte Colony-Stimulating Factor fGCSF, filgrastim) were analysed in 17 patients with malignant lymphoma and 24 patients with solid tumours, with respect to the optimum tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::6965e18452f16d1b2b6d914e70771507
https://pure.amc.nl/en/publications/mobilisation-of-blood-progenitor-cells-with-ifosfamide-and-etoposide-vp16-in-combination-with-recombinant-human-gcsf-filgrastim-in-patients-with-malignant-lymphomas-or-solid-tumours(3f8a718e-0a07-43e3-8bc9-f534027682c3).html
https://pure.amc.nl/en/publications/mobilisation-of-blood-progenitor-cells-with-ifosfamide-and-etoposide-vp16-in-combination-with-recombinant-human-gcsf-filgrastim-in-patients-with-malignant-lymphomas-or-solid-tumours(3f8a718e-0a07-43e3-8bc9-f534027682c3).html
Publikováno v:
Advances in Experimental Medicine and Biology, 338, 761-5. Springer New York
Rijnboutt, S, Strous, G, Bijleveld, E, Posthuma, G, Ratnam, M, Schornagel, J & Jansen, G 1993, ' Detergent-insolubility during the biosynthesis of membrane folate receptor-2 ', Advances in Experimental Medicine and Biology, vol. 338, pp. 761-5 .
Rijnboutt, S, Strous, G, Bijleveld, E, Posthuma, G, Ratnam, M, Schornagel, J & Jansen, G 1993, ' Detergent-insolubility during the biosynthesis of membrane folate receptor-2 ', Advances in Experimental Medicine and Biology, vol. 338, pp. 761-5 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9af89df30405fd7212534a94cf99b773
https://research.vumc.nl/en/publications/11b654be-6803-42c7-a741-b22af748f2eb
https://research.vumc.nl/en/publications/11b654be-6803-42c7-a741-b22af748f2eb
Publikováno v:
Jansen, G, Westerhof, G R, Schornagel, J H, Jackman, A L & Boyle, F T 1993, ' The reduced folate/methotrexate carrier and a membrane-associated folate binding protein as transport routes for novel antifolates : structure-activity relationships ', Advances in Experimental Medicine and Biology, vol. 338, pp. 767-70 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10172::b89893bdd0204cde79a8d93a28126f02
https://research.vumc.nl/en/publications/cc112c97-45dd-4b0e-8f48-a6d1bd06e66a
https://research.vumc.nl/en/publications/cc112c97-45dd-4b0e-8f48-a6d1bd06e66a