ECG-only explainable deep learning algorithm predicts the risk for malignant ventricular arrhythmia in phospholamban cardiomyopathy.

Autor: van de Leur RR; Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address: r.r.vandeleur@umcutrecht.nl., de Brouwer R; Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands., Bleijendaal H; Department of Cardiology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands; European Reference Network for Rare, Low-Prevalence, or Complex Diseases of the Heart (ERN GUARD-Heart); Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Verstraelen TE; Department of Cardiology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands; European Reference Network for Rare, Low-Prevalence, or Complex Diseases of the Heart (ERN GUARD-Heart)., Mahmoud B; Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands., Perez-Matos A; Department of Cardiology, St Antonius Hospital, Sneek, The Netherlands., Dickhoff C; Department of Cardiology, Dijklander Hospital, Hoorn, The Netherlands., Schoonderwoerd BA; Department of Cardiology, Medical Centre Leeuwarden, Leeuwarden, The Netherlands., Germans T; Department of Cardiology, Noordwest Hospital Group, Alkmaar, The Netherlands., Houweling A; Department of Human Genetics, Amsterdam University Medical Center, Amsterdam, The Netherlands., van der Zwaag PA; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands., Cox MGPJ; Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands., Peter van Tintelen J; European Reference Network for Rare, Low-Prevalence, or Complex Diseases of the Heart (ERN GUARD-Heart); Department of Genetics, University Medical Center Utrecht, Utrecht, The Netherlands., Te Riele ASJM; Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands., van den Berg MP; Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands., Wilde AAM; Department of Cardiology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands; European Reference Network for Rare, Low-Prevalence, or Complex Diseases of the Heart (ERN GUARD-Heart)., Doevendans PA; Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands; European Reference Network for Rare, Low-Prevalence, or Complex Diseases of the Heart (ERN GUARD-Heart); Netherlands Heart Institute, Utrecht, The Netherlands; Central Military Hospital, Utrecht, The Netherlands., de Boer RA; Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands; Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands., van Es R; Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.

Publikováno v: Heart rhythm [Heart Rhythm] 2024 Jul; Vol. 21 (7), pp. 1102-1112. Date of Electronic Publication: 2024 Feb 23.

Prediction of ventricular arrhythmia in phospholamban p.Arg14del mutation carriers-reaching the frontiers of individual risk prediction.

Autor: Verstraelen TE; Heart Center, Department of Cardiology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands., van Lint FHM; Department of Clinical Genetics, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands.; Department of Genetics, University Medical Center Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX, Utrecht, Netherlands., Bosman LP; University Medical Center Utrecht, Division Heart and Lungs, Department of Cardiology, University of Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, Netherlands., de Brouwer R; University Medical Center Groningen, Department of Cardiology, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, Netherlands., Proost VM; Heart Center, Department of Cardiology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands., Abeln BGS; Heart Center, Department of Cardiology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands., Taha K; University Medical Center Utrecht, Division Heart and Lungs, Department of Cardiology, University of Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, Netherlands., Zwinderman AH; Department of Clinical Epidemiology and Biostatistics, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands., Dickhoff C; Department of Cardiology, Dijklander Ziekenhuis Hoorn, Maelsonstraat 3, 1624 NP, Hoorn, Netherlands., Oomen T; Department of Cardiology, Antonius Ziekenhuis Sneek, Bolswarderbaan 1, 8601 ZK Sneek, Netherlands., Schoonderwoerd BA; Medical Center Leeuwarden, Department of Cardiology, Henri Dunantweg 2, 8934 AD, Leeuwarden, Netherlands., Kimman GP; Department of Cardiology, Noordwest Ziekenhuisgroep, Wilhelminalaan 12, 1815 JD, Alkmaar, Netherlands., Houweling AC; Department of Clinical Genetics, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands., Gimeno-Blanes JR; Department of Cardiology, Virgen de Arrixaca Hospital, Ctra,Murcia-Cartagena, s/n, 30120 El Palmar, Murcia, Spain.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARDHEART)., Asselbergs FW; University Medical Center Utrecht, Division Heart and Lungs, Department of Cardiology, University of Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, Netherlands.; Institute of Cardiovascular Science and Institute of Health Informatics, Faculty of Population Health Sciences, University College London, Gower St, London WC1E 6BT, UK., van der Zwaag PA; University Medical Center Groningen, Department of Clinical Genetics, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, Netherlands., de Boer RA; University Medical Center Groningen, Department of Cardiology, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, Netherlands., van den Berg MP; University Medical Center Groningen, Department of Cardiology, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, Netherlands., van Tintelen JP; Department of Clinical Genetics, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands.; Department of Genetics, University Medical Center Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX, Utrecht, Netherlands., Wilde AAM; Heart Center, Department of Cardiology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARDHEART).

Publikováno v: European heart journal [Eur Heart J] 2021 Jul 31; Vol. 42 (29), pp. 2842-2850.

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