Patient-reported data on the severity of Von Willebrand disease.

Autor: van Kwawegen CB; Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Fijnvandraat K; Amsterdam UMC, University of Amsterdam, Emma Children's Hospital, Pediatric Hematology, Amsterdam, The Netherlands.; Department of Molecular Cellular Hemostasis, Sanquin Research, Amsterdam, The Netherlands., Kruip MJHA; Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., de Meris J; Netherlands Hemophilia Society, Leiden, The Netherlands., Schols SEM; Department of Hematology, Radboud University Medical Center, Hemophilia Treatment Centre Nijmegen-Eindhoven-Maastricht, Nijmegen, The Netherlands., Meijer K; Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., van der Bom JG; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.; Jon J. van Rood Center for Clinical Transfusion Medicine, Sanquin Research, Leiden, The Netherlands., Cnossen MH; Department of Pediatric Hematology, Erasmus MC-Sophia Children's Hospital, University Medical Center Rotterdam, Rotterdam, The Netherlands., van Galen KPM; Department van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Atiq F; Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Eikenboom J; Department of Internal Medicine, Division of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands., Leebeek FWG; Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Publikováno v: Haemophilia : the official journal of the World Federation of Hemophilia [Haemophilia] 2024 Oct 15. Date of Electronic Publication: 2024 Oct 15.

Comparative analysis of thrombin generation platforms for patients with coagulation factor deficiencies: A comprehensive assessment.

Autor: Haisma B; Department of Hematology, Radboud university medical center, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands; Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands. Electronic address: bauke.haisma@radboudumc.nl., Schols SEM; Department of Hematology, Radboud university medical center, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands; Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands. Electronic address: saskia.schols@radboudumc.nl., van Oerle RGM; Central Diagnostic Laboratory, Maastricht University Medical Center+, P. Debyelaan 25, 6229 HX Maastricht, the Netherlands; Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, the Netherlands. Electronic address: rene.vanoerle@maastrichtuniversity.nl., Verbeek-Knobbe K; Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands. Electronic address: kitty.verbeek-knobbe@radboudumc.nl., Hellenbrand D; Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands; Central Diagnostic Laboratory, Maastricht University Medical Center+, P. Debyelaan 25, 6229 HX Maastricht, the Netherlands. Electronic address: dave.hellenbrand@mumc.nl., Verwoerd EJ; Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands. Electronic address: evelien.verwoerd@radboudumc.nl., Heubel-Moenen FCJI; Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands; Department of Hematology, Internal Medicine, Maastricht University Medical Center+, P. Debyelaan 25, 6229 HX Maastricht, the Netherlands. Electronic address: floor.moenen@mumc.nl., Stroobants AK; Department of Laboratory Medicine, Radboudumc Laboratory of Diagnostics, Radboud university medical center, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands. Electronic address: an.stroobants@radboudumc.nl., Meijer D; Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands. Electronic address: danielle.meijer@1forcare.nl., Rijpma SR; Department of Hematology, Radboud university medical center, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands. Electronic address: sanna.rijpma@radboudumc.nl., Henskens YMC; Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, Geert Grooteplein Zuid 10, 5425 GA Nijmegen, the Netherlands; Central Diagnostic Laboratory, Maastricht University Medical Center+, P. Debyelaan 25, 6229 HX Maastricht, the Netherlands; Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, the Netherlands. Electronic address: yvonne.henskens@mumc.nl.

Publikováno v: Thrombosis research [Thromb Res] 2024 Aug; Vol. 240, pp. 109045. Date of Electronic Publication: 2024 May 29.

Targeted exome analysis in patients with rare bleeding disorders: data from the Rare Bleeding Disorders in the Netherlands study.

Autor: Willems SPE; Department of Hematology, Radboud University Medical Center, Nijmegen, the Netherlands.; Hemophilia Treatment Center, Nijmegen - Eindhoven - Maastricht, the Netherlands., Simons A; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands., Saes JL; Department of Hematology, Radboud University Medical Center, Nijmegen, the Netherlands.; Hemophilia Treatment Center, Nijmegen - Eindhoven - Maastricht, the Netherlands., Weiss M; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands., Rijpma S; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Nijmegen, the Netherlands., Schoormans S; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Nijmegen, the Netherlands., Meijer K; Department of Hematology, University Medical Center Groningen, Groningen, the Netherlands., Cnossen MH; Department of Pediatric Hematology and Oncology, Erasmus Medical Centre Sophia Children's Hospital, University Medical Center Rotterdam, Rotterdam, the Netherlands., Schutgens REG; Center for Benign Haematology, Thrombosis and Haemostasis, van Creveldkliniek, University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands., van Es N; Department of Vascular Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Pulmonary Hypertension & Thrombosis, Amsterdam, the Netherlands., Nieuwenhuizen L; Hemophilia Treatment Center, Nijmegen - Eindhoven - Maastricht, the Netherlands.; Department of Hematology, Máxima Medical Center Eindhoven, Eindhoven, the Netherlands., den Exter PL; Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands., Kruis IC; Netherlands Hemophilia Society, Nijkerk, the Netherlands., Blijlevens NMA; Department of Hematology, Radboud University Medical Center, Nijmegen, the Netherlands., van Heerde WL; Department of Hematology, Radboud University Medical Center, Nijmegen, the Netherlands.; Hemophilia Treatment Center, Nijmegen - Eindhoven - Maastricht, the Netherlands.; Enzyre BV, Novio Tech Campus, Nijmegen, the Netherlands., Schols SEM; Department of Hematology, Radboud University Medical Center, Nijmegen, the Netherlands.; Hemophilia Treatment Center, Nijmegen - Eindhoven - Maastricht, the Netherlands.

Publikováno v: Research and practice in thrombosis and haemostasis [Res Pract Thromb Haemost] 2024 Jun 17; Vol. 8 (4), pp. 102477. Date of Electronic Publication: 2024 Jun 17 (Print Publication: 2024).

Type 1 VWD classification revisited: novel insights from combined analysis of the LoVIC and WiN studies.

Autor: Atiq F; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Haematology, Erasmus University Medical Center-Erasmus MC, Rotterdam, The Netherlands., Blok R; Department of Haematology, Erasmus University Medical Center-Erasmus MC, Rotterdam, The Netherlands., van Kwawegen CB; Department of Haematology, Erasmus University Medical Center-Erasmus MC, Rotterdam, The Netherlands., Doherty D; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.; National Coagulation Centre, St James's Hospital, Dublin, Ireland., Lavin M; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.; National Coagulation Centre, St James's Hospital, Dublin, Ireland., van der Bom JG; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., O'Connell NM; National Coagulation Centre, St James's Hospital, Dublin, Ireland., de Meris J; Netherlands Hemophilia Society, Leiden, The Netherlands., Ryan K; National Coagulation Centre, St James's Hospital, Dublin, Ireland., Schols SEM; Department of Hematology, Radboud University Medical Center, Nijmegen and Hemophilia Treatment Center, Nijmegen-Eindhoven-Maastricht, The Netherlands., Byrne M; National Coagulation Centre, St James's Hospital, Dublin, Ireland., Heubel-Moenen FCJI; Department of Hematology, Maastricht University Medical Center, Maastricht, The Netherlands., van Galen KPM; Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Preston RJS; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland., Cnossen MH; Department of Pediatric Hematology and Oncology, Erasmus MC, University Medical Center-Sophia Children's Hospital Rotterdam, Rotterdam, The Netherlands., Fijnvandraat K; Department of Pediatric Hematology, Emma Children's Hospital, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands., Baker RI; Western Australia Centre for Thrombosis and Haemostasis, Perth Blood Institute, Murdoch University, Perth, WA, Australia.; Irish-Australian Blood Collaborative Network, Dublin, Ireland., Meijer K; Department of Hematology, University Medical Center Groningen, Groningen, The Netherlands., James P; Department of Medicine, Queen's University, Kingston, ON, Canada., Di Paola J; Department of Pediatrics, School of Medicine, Washington University in St. Louis, St. Louis, MO., Eikenboom J; Department of Internal Medicine, Division of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands., Leebeek FWG; Department of Haematology, Erasmus University Medical Center-Erasmus MC, Rotterdam, The Netherlands., O'Donnell JS; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.; National Coagulation Centre, St James's Hospital, Dublin, Ireland.; Irish-Australian Blood Collaborative Network, Dublin, Ireland.

Publikováno v: Blood [Blood] 2024 Apr 04; Vol. 143 (14), pp. 1414-1424.

Pharmacokinetic-Pharmacodynamic Modelling in Hemophilia A: Relating Thrombin and Plasmin Generation to Factor VIII Activity After Administration of a VWF/FVIII Concentrate.

Autor: Valke LLFG; Department of Hematology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.; Hemophilia Treatment Center, Nijmegen-Eindhoven-Maastricht, The Netherlands., Cloesmeijer ME; Department of Hospital Pharmacy-Clinical Pharmacology, Amsterdam University Medical Center, Location AMC, Amsterdam, The Netherlands., Mansouritorghabeh H; Clinical Research Development Unit, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Barteling W; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands., Blijlevens NMA; Department of Hematology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands., Cnossen MH; Department of Pediatric Hematology and Oncology, Erasmus MC Sophia Children's Hospital, University Medical Center Rotterdam, Rotterdam, The Netherlands., Mathôt RAA; Department of Hospital Pharmacy-Clinical Pharmacology, Amsterdam University Medical Center, Location AMC, Amsterdam, The Netherlands., Schols SEM; Department of Hematology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.; Hemophilia Treatment Center, Nijmegen-Eindhoven-Maastricht, The Netherlands., van Heerde WL; Department of Hematology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. waander.vanheerde@radboudumc.nl.; Hemophilia Treatment Center, Nijmegen-Eindhoven-Maastricht, The Netherlands. waander.vanheerde@radboudumc.nl.; Enzyre BV, Novio Tech Campus, Nijmegen, The Netherlands. waander.vanheerde@radboudumc.nl.

Publikováno v: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2024 Mar; Vol. 49 (2), pp. 191-205. Date of Electronic Publication: 2024 Feb 17.