Zobrazeno 1 - 10 of 313 pro vyhledávání: '"Schoelch C"'
1
Akademický článek
Hepatic improvement within 27 days of avenciguat treatment in Child-Pugh A cirrhosis detected by an oral cholate challenge test.
Autor: Lawitz EJ; Texas Liver Institute, University Transplant Center, University of Texas Health, San Antonio, Texas, USA., Ertle J; Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany., Schoelch C; Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany., Gashaw I; Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany., McRae MP; Custom DX Solutions LLC, Houston, Texas, USA., Helmke SM; HepQuant, LLC, Denver, Colorado, USA., Everson GT; HepQuant, LLC, Denver, Colorado, USA.
Publikováno v: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society [Liver Transpl] 2024 Oct 01; Vol. 30 (10), pp. 982-990. Date of Electronic Publication: 2024 Jun 12.
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2
Akademický článek
Obesity-related inflammatory protein signature in cardiovascular clinical outcomes: results from the Gutenberg Health Study.
Autor: Panova-Noeva M; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany.; Center for Thrombosis and Haemostasis, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany., Koeck T; Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany., Schoelch C; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Schulz A; Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany., Prochaska JH; Center for Thrombosis and Haemostasis, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.; Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany., Michal M; German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany.; Department of Psychosomatic Medicine and Psychotherapy, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany., Strauch K; Institute for Medical Biometrics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany., Schuster AK; Department of Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany., Lackner KJ; German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany., Münzel T; Center for Thrombosis and Haemostasis, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany.; Department of Cardiology-Cardiology I, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany., Hennige AM; Therapeutic Area CardioMetabolism & Respiratory, Boehringer Ingelheim International GmbH, Biberach, Germany., Wild PS; Center for Thrombosis and Haemostasis, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.; Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany.; Institute of Molecular Biology (IMB), Mainz, Germany.
Publikováno v: Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2024 Jun; Vol. 32 (6), pp. 1198-1209. Date of Electronic Publication: 2024 Apr 25.
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3
Akademický článek
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4
Akademický článek
A randomised Phase IIa trial of amine oxidase copper-containing 3 (AOC3) inhibitor BI 1467335 in adults with non-alcoholic steatohepatitis.
Autor: Newsome PN; National Institute for Health Research, Birmingham Biomedical Research Centre at University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK. p.n.newsome@bham.ac.uk.; Centre for Liver & Gastrointestinal Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK. p.n.newsome@bham.ac.uk., Sanyal AJ; Virginia Commonwealth University, Richmond, VA, USA., Neff G; Covenant Research, Sarasota, FL, USA., Schattenberg JM; Metabolic Liver Research Program University Medical Center, Mainz, Germany., Ratziu V; Sorbonne Université, Institute of Cardiometabolism and Nutrition, Hospital Pitié-Salpêtrière, Paris, France., Ertle J; Boehringer Ingelheim, Ingelheim am Rhein, Germany., Link J; Boehringer Ingelheim, Biberach, Germany., Mackie A; Boehringer Ingelheim, Biberach, Germany., Schoelch C; Boehringer Ingelheim, Biberach, Germany., Lawitz E; Texas Liver Institute, University of Texas Health, San Antonio, TX, USA.
Publikováno v: Nature communications [Nat Commun] 2023 Nov 06; Vol. 14 (1), pp. 7151. Date of Electronic Publication: 2023 Nov 06.
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5
Akademický článek
Safety and pharmacokinetics of BI 685509, a soluble guanylyl cyclase activator, in patients with cirrhosis: A randomized Phase Ib study.
Autor: Lawitz EJ; The Texas Liver Institute, University of Texas Health, San Antonio, Texas, USA., Reiberger T; Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria.; Christian Doppler Laboratory for Portal Hypertension and Liver Fibrosis, Medical University of Vienna, Vienna, Austria., Schattenberg JM; Metabolic Liver Research Program, I. Department of Medicine, University Medical Center Mainz, Mainz, Rhineland Palatinate, Germany., Schoelch C; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Coxson HO; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Wong D; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, USA., Ertle J; Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany.
Publikováno v: Hepatology communications [Hepatol Commun] 2023 Oct 27; Vol. 7 (11). Date of Electronic Publication: 2023 Oct 27 (Print Publication: 2023).
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6
Akademický článek
NAFLD and NASH biomarker qualification in the LITMUS consortium - Lessons learned.
Autor: Rasmussen DGK; Nordic Bioscience, Denmark. Electronic address: dgr@nordicbio.com., Anstee QM; Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, United Kingdom; Newcastle NIHR Biomedical Research Centre, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, United Kingdom., Torstenson R; Astrazeneca, Regulatory Affairs, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, Gothenburg, Sweden., Golding B; Roche Diagnostics International, Rotkreuz, Switzerland., Patterson SD; Gilead Sciences, Inc, Foster City, California, USA., Brass C; Novartis, East Hanover, NJ 07936, USA., Thakker P; Takeda Development Center Americas, Inc., 95 Hayden Avenue, Lexington, MA 02421, USA., Harrison S; Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Billin AN; Gilead Sciences, Inc, Foster City, California, USA., Schuppan D; Institute of Translational Immunology and Research Center for Immune Therapy, Mainz University Medical Center, 55131, Mainz, Germany; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA., Dufour JF; Centre for Digestive Diseases, Lausanne, Switzerland., Andersson A; Perspectum, Oxford, OX4 2LL, United Kingdom., Wigley I; Perspectum, Oxford, OX4 2LL, United Kingdom., Shumbayawonda E; Perspectum, Oxford, OX4 2LL, United Kingdom., Dennis A; Perspectum, Oxford, OX4 2LL, United Kingdom., Schoelch C; Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany., Ratziu V; Sorbonne University, Paris, France; Pitié-Salpêtrière Hospital, Paris, France., Yunis C; Global Product Development, Internal Medicine and Hospital, Pfizer Inc, Florida, USA., Bossuyt P; Department of Epidemiology and Data Science, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, the Netherlands., Karsdal MA; Nordic Bioscience, Denmark.
Publikováno v: Journal of hepatology [J Hepatol] 2023 Apr; Vol. 78 (4), pp. 852-865. Date of Electronic Publication: 2022 Dec 14.
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7
Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux
Autor: Perotin, Jeanne-Marie, Schofield, James PR, Wilson, Susan J, Ward, Jonathan, Brandsma, Joost, Strazzeri, Fabio, Bansal, Aruna, Yang, Xian, Rowe, Anthony, Corfield, Julie, Lutter, Rene, Shaw, Dominick E, Bakke, Per S, Caruso, Massimo, Dahlen, Barbro, Fowler, Stephen J, Horvath, Ildiko, Howarth, Peter, Krug, Norbert, Montuschi, Paolo, Sanak, Marek, Sandstrom, Thomas, Sun, Kai, Pandis, Ioannis, Auffray, Charles, De Meulder, Bertrand, Lefaudeux, Diane, Riley, John H, Sousa, Ana R, Dahlen, Sven-Erik, Adcock, Ian M, Chung, Kian Fan, Sterk, Peter J, Skipp, Paul J, Collins, Jane E, Davies, Donna E, Djukanovic, Ratko, Adcock, IM, Ahmed, H, Auffray, C, Bakke, P, Banssal, AT, Baribaud, F, Bates, S, Bel, EH, Bigler, J, Bisgaard, H, Boedigheimer, MJ, Bonnelykke, K, Brandsma, J, Brinkman, P, Bucchioni, E, Burg, D, Bush, A, Caruso, M, Chaiboonchoe, A, Chanez, P, Chung, KF, Compton, CH, Corfield, J, D'Amico, A, Dahlen, SE, De Meulder, B, Djukanovic, R, Erpenbeck, VJ, Erzen, D, Fichtner, K, Fitch, N, Fleming, LJ, Formaggio, E, Fowler, SJ, Frey, U, Gahlemann, M, Geiser, T, Guo, Y, Hashimoto, S, Haughney, J, Hedlin, G, Hekking, PW, Higenbottam, T, Hohlfeld, JM, Holweg, C, Horvath, I, Howarth, P, James, AJ, Knowles, R, Knox, AJ, Krug, N, Lefaudeux, D, Loza, MJ, Lutter, R, Manta, A, Masefield, S, Matthews, JG, Mazein, A, Meiser, A, Middelveld, RJM, Miralpeix, M, Montuschi, P, Mores, N, Murray, CS, Musial, J, Myles, D, Pahus, L, Pandis, I, Pavlidis, S, Powell, P, Pratico, G, Puig Valls, M, Rao, N, Riley, J, Roberts, A, Roberts, G., Rowe, A, Sandstrom, T, Seibold, W, Selby, A, Shaw, DE, Sigmund, R, Singer, F, Skipp, PJ, Sousa, AR, Sterk, PJ, Sun, K, Thornton, B, van Aalderen, WM, van Geest, M, Vestbo, J, Vissing, NH, Wagener, AH, Wagers, SS, Weiszhart, Z, Wheelock, CE, Wilson, SJ, Aliprantis, Antonios, Allen, David, Alving, Kjell, Badorrek, P, Balgoma, David, Ballereau, S, Barber, Clair, Batuwitage, Manohara Kanangana, Bautmans, An, Bedding, A, Behndig, AF, Beleta, Jorge, Berglind, A, Berton, A, Bochenek, G, Braun, A, Campagna, D, Carayannopoulos, L, Casaulta, C, Chaleckis, Romanas, Dahlen, B, Davison, T, De Alba, J, De Lepeleire, I, Dekker, T, Delin, I, Dennison, P, Dijkhuis, A, Dodson, P, Dyson, K, Edwards, J, El Hadjam, L, Emma, R, Ericsson, M, Faulenbach, C, Flood, Breda, Galffy, G, Gallart, H, Garissi, D, Gent, J., Gerhardsson de Verdier, M, Gibeon, D, Gomez, Cristina, Gove, K, Guillmant-Farry, E, Henriksson, E, Hewitt, L, Hoda, U, Hu, Richard, Hu, S, Hu, X, Jeyasingham, E, Johnson, K, Jullian, N, Kamphuis, J, Kennington, EJ, Kerry, D, Kerry, G, Klueglich, M, Knobel, H, Kolmert, Johan, Konradsen, JR, Kots, M, Kretsos, Kosmas, Krueger, L, Kuo, S, Kupczyk, M, Lambrecht, Bart, Lantz, A-S, Larminie, Christopher, Larsson, LX, Latzin, P, Lazarinis, N, Lemonnier, N, Lone-Latif, S, Lowe, LA, Marouzet, L, Martin, J, Mathon, C, McEvoy, L, Meah, S, Menzies-Gow, A, Metcalf, L, Mikus, M, Monk, P, Naz, S, Nething, K, Nicholas, B, Nihlen, U, Nilsson, Peter, Niven, R, Nordlund, B, Nsubuga, S, Ostling, J, Pacino, A, Palkonen, S, Pellet, J, Pennazza, G, Petren, A, Pink, S, Pison, C, Postle, A, Rahman-Amin, M, Ravanetti, L, Ray, E, Reinke, S, Reynolds, L, Riemann, K, Robberechts, Martine, Rocha, JP, Rossios, C, Russell, K, Rutgers, M, Santini, G, Santoninco, M, Saqi, M, Schoelch, C, Schofield, JPR, Scott, S, Sehgal, N, Sjodin, M, Smids, B, Smith, Caroline, Smith, J, Smith, KM, Soderman, P, Sogbessan, A, Spycher, F, Staykova, D, Stephan, S, Stokholm, J, Strandberg, K, Sunther, M, Szentkereszty, M, Tamasi, L, Tariq, K, Thorngren, J-O, Thorsen, Jonathan, Valente, S, van de Pol, Marianne, van Drunen, CM, Van Eyll, J, Versnel, J, Vink, A, von Garnier, C, Vyas, A, Wald, F, Walker, S, Ward, J, Wetzel, K, Wiegman, C, Williams, S, Yang, X, Yeyasingham, E, Yu, W, Zetterquist, W, Zolkipli, Z, Zwinderman, AH, Prins, J-B, Visintin, L, Evans, H, Puhl, M, Buzermaniene, L, Hudson, V, Bond, L, de Boer, P, Widdershoven, G, Supple, D, Hamerlijnck, D, Negus, J, Sergison, L, Onstein, S, MacNee, W, Bernardini, R, Bont, Louis, Wecksell, P-A, Draper, Aleksandra, Gozzard, Neil
Publikováno v: EUROPEAN RESPIRATORY JOURNAL
European respiratory journal, 53(6). European Respiratory Society
European Respiratory Journal
U-BIOPRED Study Group 2019, ' Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux ', The European respiratory journal, vol. 53, no. 6, 1900453, pp. 1-7 . https://doi.org/10.1183/13993003.00453-2019
Eur Respir J
European Respiratory Journal, European Respiratory Society, 2019, 53 (6), pp.1900453. ⟨10.1183/13993003.00453-2019⟩
Gastro-oesophageal reflux disease (GORD) and obesity are associated with frequent exacerbations and poor quality of life in asthmatics. Multiple mechanisms have been proposed for the effect of obesity, including modification of inflammation affecting
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dbe1120c9d9de400acc7cb24e795861
https://hdl.handle.net/1854/LU-8625684
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Akademický článek
The Combination of MR Elastography and Proton Density Fat Fraction Improves Diagnosis of Nonalcoholic Steatohepatitis.
Autor: Alsaqal S; Department of Surgical Sciences, Section of Radiology, Uppsala University, Uppsala, Sweden., Hockings P; Antaros Medical, Mölndal, Sweden., Ahlström H; Department of Surgical Sciences, Section of Radiology, Uppsala University, Uppsala, Sweden.; Antaros Medical, Mölndal, Sweden., Gummesson A; Department of Clinical Genetics and Genomics, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden., Hedström A; Antaros Medical, Mölndal, Sweden., Hulthe J; Antaros Medical, Mölndal, Sweden., Johansson L; Antaros Medical, Mölndal, Sweden., Niessen HG; Department of Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Schoelch C; Department of Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Schultheis C; Department of Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Vessby J; Department of Medical Sciences, Section of Gastroenterology and Hepatology, Uppsala University, Uppsala, Sweden., Wanders A; Department of Clinical Medicine, Aalborg University and Aalborg University Hospital, Aalborg, Denmark., Rorsman F; Department of Medical Sciences, Section of Gastroenterology and Hepatology, Uppsala University, Uppsala, Sweden., Ebeling Barbier C; Department of Surgical Sciences, Section of Radiology, Uppsala University, Uppsala, Sweden.
Publikováno v: Journal of magnetic resonance imaging : JMRI [J Magn Reson Imaging] 2022 Aug; Vol. 56 (2), pp. 368-379. Date of Electronic Publication: 2021 Dec 25.
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